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RFK (riboflavin kinase)

Identity

Alias_symbol (synonym)FLJ11149
RIFK
Other alias
HGNC (Hugo) RFK
LocusID (NCBI) 55312
Atlas_Id 43617
Location 9q21.13  [Link to chromosome band 9q21]
Location_base_pair Starts at 76385517 and ends at 76394528 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CBX4 (17q25.3) / RFK (9q21.13)RFK (9q21.13) / LYZ (12q15)SGCD (5q33.3) / RFK (9q21.13)
CBX4 17q25.3 / RFK 9q21.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RFK   30324
Cards
Entrez_Gene (NCBI)RFK  55312  riboflavin kinase
AliasesRIFK
GeneCards (Weizmann)RFK
Ensembl hg19 (Hinxton)ENSG00000135002 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135002 [Gene_View]  chr9:76385517-76394528 [Contig_View]  RFK [Vega]
ICGC DataPortalENSG00000135002
TCGA cBioPortalRFK
AceView (NCBI)RFK
Genatlas (Paris)RFK
WikiGenes55312
SOURCE (Princeton)RFK
Genetics Home Reference (NIH)RFK
Genomic and cartography
GoldenPath hg38 (UCSC)RFK  -     chr9:76385517-76394528 -  9q21.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RFK  -     9q21.13   [Description]    (hg19-Feb_2009)
EnsemblRFK - 9q21.13 [CytoView hg19]  RFK - 9q21.13 [CytoView hg38]
Mapping of homologs : NCBIRFK [Mapview hg19]  RFK [Mapview hg38]
OMIM613010   
Gene and transcription
Genbank (Entrez)AF038172 AK002011 AK123933 AK307079 AK315734
RefSeq transcript (Entrez)NM_018339
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RFK
Cluster EST : UnigeneHs.37558 [ NCBI ]
CGAP (NCI)Hs.37558
Alternative Splicing GalleryENSG00000135002
Gene ExpressionRFK [ NCBI-GEO ]   RFK [ EBI - ARRAY_EXPRESS ]   RFK [ SEEK ]   RFK [ MEM ]
Gene Expression Viewer (FireBrowse)RFK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55312
GTEX Portal (Tissue expression)RFK
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969G6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969G6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969G6
Splice isoforms : SwissVarQ969G6
Catalytic activity : Enzyme2.7.1.26 [ Enzyme-Expasy ]   2.7.1.262.7.1.26 [ IntEnz-EBI ]   2.7.1.26 [ BRENDA ]   2.7.1.26 [ KEGG ]   
PhosPhoSitePlusQ969G6
Domains : Interpro (EBI)Riboflavin_kinase    Riboflavin_kinase_bac/euk    Riboflavin_kinase_domain   
Domain families : Pfam (Sanger)Flavokinase (PF01687)   
Domain families : Pfam (NCBI)pfam01687   
Domain families : Smart (EMBL)Flavokinase (SM00904)  
Conserved Domain (NCBI)RFK
DMDM Disease mutations55312
Blocks (Seattle)RFK
PDB (SRS)1NB0    1NB9    1P4M    1Q9S   
PDB (PDBSum)1NB0    1NB9    1P4M    1Q9S   
PDB (IMB)1NB0    1NB9    1P4M    1Q9S   
PDB (RSDB)1NB0    1NB9    1P4M    1Q9S   
Structural Biology KnowledgeBase1NB0    1NB9    1P4M    1Q9S   
SCOP (Structural Classification of Proteins)1NB0    1NB9    1P4M    1Q9S   
CATH (Classification of proteins structures)1NB0    1NB9    1P4M    1Q9S   
SuperfamilyQ969G6
Human Protein AtlasENSG00000135002
Peptide AtlasQ969G6
HPRD17969
IPIIPI00099995   IPI00980776   IPI00947016   
Protein Interaction databases
DIP (DOE-UCLA)Q969G6
IntAct (EBI)Q969G6
FunCoupENSG00000135002
BioGRIDRFK
STRING (EMBL)RFK
ZODIACRFK
Ontologies - Pathways
QuickGOQ969G6
Ontology : AmiGOATP binding  cytoplasm  mitochondrion  cytosol  riboflavin metabolic process  apoptotic process  riboflavin kinase activity  riboflavin kinase activity  riboflavin biosynthetic process  FMN biosynthetic process  phosphorylation  positive regulation of NAD(P)H oxidase activity  metal ion binding  reactive oxygen species metabolic process  
Ontology : EGO-EBIATP binding  cytoplasm  mitochondrion  cytosol  riboflavin metabolic process  apoptotic process  riboflavin kinase activity  riboflavin kinase activity  riboflavin biosynthetic process  FMN biosynthetic process  phosphorylation  positive regulation of NAD(P)H oxidase activity  metal ion binding  reactive oxygen species metabolic process  
Pathways : KEGGRiboflavin metabolism   
NDEx NetworkRFK
Atlas of Cancer Signalling NetworkRFK
Wikipedia pathwaysRFK
Orthology - Evolution
OrthoDB55312
GeneTree (enSembl)ENSG00000135002
Phylogenetic Trees/Animal Genes : TreeFamRFK
HOVERGENQ969G6
HOGENOMQ969G6
Homologs : HomoloGeneRFK
Homology/Alignments : Family Browser (UCSC)RFK
Gene fusions - Rearrangements
Fusion : MitelmanCBX4/RFK [17q25.3/9q21.13]  [t(9;17)(q21;q25)]  
Fusion: TCGACBX4 17q25.3 RFK 9q21.13 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRFK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RFK
dbVarRFK
ClinVarRFK
1000_GenomesRFK 
Exome Variant ServerRFK
ExAC (Exome Aggregation Consortium)RFK (select the gene name)
Genetic variants : HAPMAP55312
Genomic Variants (DGV)RFK [DGVbeta]
DECIPHERRFK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRFK 
Mutations
ICGC Data PortalRFK 
TCGA Data PortalRFK 
Broad Tumor PortalRFK
OASIS PortalRFK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRFK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRFK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch RFK
DgiDB (Drug Gene Interaction Database)RFK
DoCM (Curated mutations)RFK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RFK (select a term)
intoGenRFK
Cancer3DRFK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613010   
Orphanet
MedgenRFK
Genetic Testing Registry RFK
NextProtQ969G6 [Medical]
TSGene55312
GENETestsRFK
Target ValidationRFK
Huge Navigator RFK [HugePedia]
snp3D : Map Gene to Disease55312
BioCentury BCIQRFK
ClinGenRFK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55312
Chemical/Pharm GKB GenePA134916697
Clinical trialRFK
Miscellaneous
canSAR (ICR)RFK (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRFK
EVEXRFK
GoPubMedRFK
iHOPRFK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:28:35 CEST 2017

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