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RGS4 (regulator of G protein signaling 4)

Identity

Alias_namesSCZD9
regulator of G-protein signalling 4
schizophrenia disorder 9
Other aliasRGP4
HGNC (Hugo) RGS4
LocusID (NCBI) 5999
Atlas_Id 47334
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 163068606 and ends at 163076802 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RGS4 (1q23.3) / TSPAN9 (12p13.33)UAP1 (1q23.3) / RGS4 (1q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RGS4   10000
Cards
Entrez_Gene (NCBI)RGS4  5999  regulator of G protein signaling 4
AliasesRGP4; SCZD9
GeneCards (Weizmann)RGS4
Ensembl hg19 (Hinxton)ENSG00000117152 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000117152 [Gene_View]  chr1:163068606-163076802 [Contig_View]  RGS4 [Vega]
ICGC DataPortalENSG00000117152
TCGA cBioPortalRGS4
AceView (NCBI)RGS4
Genatlas (Paris)RGS4
WikiGenes5999
SOURCE (Princeton)RGS4
Genetics Home Reference (NIH)RGS4
Genomic and cartography
GoldenPath hg38 (UCSC)RGS4  -     chr1:163068606-163076802 +  1q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RGS4  -     1q23.3   [Description]    (hg19-Feb_2009)
EnsemblRGS4 - 1q23.3 [CytoView hg19]  RGS4 - 1q23.3 [CytoView hg38]
Mapping of homologs : NCBIRGS4 [Mapview hg19]  RGS4 [Mapview hg38]
OMIM602516   
Gene and transcription
Genbank (Entrez)AB209019 AF493928 AK093959 AK096204 AK295540
RefSeq transcript (Entrez)NM_001102445 NM_001113380 NM_001113381 NM_005613
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RGS4
Cluster EST : UnigeneHs.386726 [ NCBI ]
CGAP (NCI)Hs.386726
Alternative Splicing GalleryENSG00000117152
Gene ExpressionRGS4 [ NCBI-GEO ]   RGS4 [ EBI - ARRAY_EXPRESS ]   RGS4 [ SEEK ]   RGS4 [ MEM ]
Gene Expression Viewer (FireBrowse)RGS4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5999
GTEX Portal (Tissue expression)RGS4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49798   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49798  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49798
Splice isoforms : SwissVarP49798
PhosPhoSitePlusP49798
Domaine pattern : Prosite (Expaxy)RGS (PS50132)   
Domains : Interpro (EBI)RGS    RGS_subdom1   
Domain families : Pfam (Sanger)RGS (PF00615)   
Domain families : Pfam (NCBI)pfam00615   
Domain families : Smart (EMBL)RGS (SM00315)  
Conserved Domain (NCBI)RGS4
DMDM Disease mutations5999
Blocks (Seattle)RGS4
SuperfamilyP49798
Human Protein AtlasENSG00000117152
Peptide AtlasP49798
HPRD03947
IPIIPI00028112   IPI00556480   IPI00643632   IPI00477871   IPI00855823   IPI00983020   IPI00975643   
Protein Interaction databases
DIP (DOE-UCLA)P49798
IntAct (EBI)P49798
FunCoupENSG00000117152
BioGRIDRGS4
STRING (EMBL)RGS4
ZODIACRGS4
Ontologies - Pathways
QuickGOP49798
Ontology : AmiGOinactivation of MAPK activity  G-protein alpha-subunit binding  GTPase activator activity  calmodulin binding  nucleus  cytoplasm  cytosol  plasma membrane  regulation of G-protein coupled receptor protein signaling pathway  protein complex  positive regulation of GTPase activity  negative regulation of G-protein coupled receptor protein signaling pathway  
Ontology : EGO-EBIinactivation of MAPK activity  G-protein alpha-subunit binding  GTPase activator activity  calmodulin binding  nucleus  cytoplasm  cytosol  plasma membrane  regulation of G-protein coupled receptor protein signaling pathway  protein complex  positive regulation of GTPase activity  negative regulation of G-protein coupled receptor protein signaling pathway  
NDEx NetworkRGS4
Atlas of Cancer Signalling NetworkRGS4
Wikipedia pathwaysRGS4
Orthology - Evolution
OrthoDB5999
GeneTree (enSembl)ENSG00000117152
Phylogenetic Trees/Animal Genes : TreeFamRGS4
HOVERGENP49798
HOGENOMP49798
Homologs : HomoloGeneRGS4
Homology/Alignments : Family Browser (UCSC)RGS4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRGS4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RGS4
dbVarRGS4
ClinVarRGS4
1000_GenomesRGS4 
Exome Variant ServerRGS4
ExAC (Exome Aggregation Consortium)RGS4 (select the gene name)
Genetic variants : HAPMAP5999
Genomic Variants (DGV)RGS4 [DGVbeta]
DECIPHERRGS4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRGS4 
Mutations
ICGC Data PortalRGS4 
TCGA Data PortalRGS4 
Broad Tumor PortalRGS4
OASIS PortalRGS4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRGS4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRGS4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RGS4
DgiDB (Drug Gene Interaction Database)RGS4
DoCM (Curated mutations)RGS4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RGS4 (select a term)
intoGenRGS4
Cancer3DRGS4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602516   
Orphanet
MedgenRGS4
Genetic Testing Registry RGS4
NextProtP49798 [Medical]
TSGene5999
GENETestsRGS4
Target ValidationRGS4
Huge Navigator RGS4 [HugePedia]
snp3D : Map Gene to Disease5999
BioCentury BCIQRGS4
ClinGenRGS4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5999
Chemical/Pharm GKB GenePA34375
Clinical trialRGS4
Miscellaneous
canSAR (ICR)RGS4 (select the gene name)
Probes
Litterature
PubMed121 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRGS4
EVEXRGS4
GoPubMedRGS4
iHOPRGS4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:53:10 CEST 2017

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