Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

RGS5 (regulator of G-protein signaling 5)

Identity

Alias_namesregulator of G-protein signalling 5
Other aliasMST092
MST106
MST129
MSTP032
MSTP092
MSTP106
MSTP129
HGNC (Hugo) RGS5
LocusID (NCBI) 8490
Atlas_Id 46825
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 163112089 and ends at 163172963 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FKBP3 (14q21.2) / RGS5 (1q23.3)RGS5 (1q23.3) / MALAT1 (11q13.1)RGS5 (1q23.3) / RGS5 (1q23.3)
RGS5 (1q23.3) / SPIN1 (9q22.1)RGS5 (1q23.3) / UBL3 (13q12.3)ZNF521 (18q11.2) / RGS5 (1q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RGS5   10001
Cards
Entrez_Gene (NCBI)RGS5  8490  regulator of G-protein signaling 5
AliasesMST092; MST106; MST129; MSTP032; 
MSTP092; MSTP106; MSTP129
GeneCards (Weizmann)RGS5
Ensembl hg19 (Hinxton)ENSG00000143248 [Gene_View]  chr1:163112089-163172963 [Contig_View]  RGS5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000143248 [Gene_View]  chr1:163112089-163172963 [Contig_View]  RGS5 [Vega]
ICGC DataPortalENSG00000143248
TCGA cBioPortalRGS5
AceView (NCBI)RGS5
Genatlas (Paris)RGS5
WikiGenes8490
SOURCE (Princeton)RGS5
Genetics Home Reference (NIH)RGS5
Genomic and cartography
GoldenPath hg19 (UCSC)RGS5  -     chr1:163112089-163172963 -  1q23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RGS5  -     1q23.3   [Description]    (hg38-Dec_2013)
EnsemblRGS5 - 1q23.3 [CytoView hg19]  RGS5 - 1q23.3 [CytoView hg38]
Mapping of homologs : NCBIRGS5 [Mapview hg19]  RGS5 [Mapview hg38]
OMIM145500   603276   
Gene and transcription
Genbank (Entrez)AA486366 AA805263 AA974387 AB008109 AF030108
RefSeq transcript (Entrez)NM_001195303 NM_001254748 NM_001254749 NM_003617 NM_025226
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_027731 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)RGS5
Cluster EST : UnigeneHs.677623 [ NCBI ]
CGAP (NCI)Hs.677623
Alternative Splicing GalleryENSG00000143248
Gene ExpressionRGS5 [ NCBI-GEO ]   RGS5 [ EBI - ARRAY_EXPRESS ]   RGS5 [ SEEK ]   RGS5 [ MEM ]
Gene Expression Viewer (FireBrowse)RGS5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8490
GTEX Portal (Tissue expression)RGS5
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15539   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15539  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15539
Splice isoforms : SwissVarO15539
PhosPhoSitePlusO15539
Domaine pattern : Prosite (Expaxy)RGS (PS50132)   
Domains : Interpro (EBI)RGS    RGS_subdom1   
Domain families : Pfam (Sanger)RGS (PF00615)   
Domain families : Pfam (NCBI)pfam00615   
Domain families : Smart (EMBL)RGS (SM00315)  
Conserved Domain (NCBI)RGS5
DMDM Disease mutations8490
Blocks (Seattle)RGS5
PDB (SRS)2CRP   
PDB (PDBSum)2CRP   
PDB (IMB)2CRP   
PDB (RSDB)2CRP   
Structural Biology KnowledgeBase2CRP   
SCOP (Structural Classification of Proteins)2CRP   
CATH (Classification of proteins structures)2CRP   
SuperfamilyO15539
Human Protein AtlasENSG00000143248
Peptide AtlasO15539
HPRD04471
IPIIPI00183077   IPI00549586   IPI00478269   IPI00984574   IPI00977109   IPI00975789   
Protein Interaction databases
DIP (DOE-UCLA)O15539
IntAct (EBI)O15539
FunCoupENSG00000143248
BioGRIDRGS5
STRING (EMBL)RGS5
ZODIACRGS5
Ontologies - Pathways
QuickGOO15539
Ontology : AmiGOGTPase activator activity  cytoplasm  cytoplasm  plasma membrane  regulation of G-protein coupled receptor protein signaling pathway  negative regulation of signal transduction  positive regulation of GTPase activity  
Ontology : EGO-EBIGTPase activator activity  cytoplasm  cytoplasm  plasma membrane  regulation of G-protein coupled receptor protein signaling pathway  negative regulation of signal transduction  positive regulation of GTPase activity  
NDEx NetworkRGS5
Atlas of Cancer Signalling NetworkRGS5
Wikipedia pathwaysRGS5
Orthology - Evolution
OrthoDB8490
GeneTree (enSembl)ENSG00000143248
Phylogenetic Trees/Animal Genes : TreeFamRGS5
HOVERGENO15539
HOGENOMO15539
Homologs : HomoloGeneRGS5
Homology/Alignments : Family Browser (UCSC)RGS5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRGS5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RGS5
dbVarRGS5
ClinVarRGS5
1000_GenomesRGS5 
Exome Variant ServerRGS5
ExAC (Exome Aggregation Consortium)RGS5 (select the gene name)
Genetic variants : HAPMAP8490
Genomic Variants (DGV)RGS5 [DGVbeta]
DECIPHER (Syndromes)1:163112089-163172963  ENSG00000143248
CONAN: Copy Number AnalysisRGS5 
Mutations
ICGC Data PortalRGS5 
TCGA Data PortalRGS5 
Broad Tumor PortalRGS5
OASIS PortalRGS5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRGS5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRGS5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RGS5
DgiDB (Drug Gene Interaction Database)RGS5
DoCM (Curated mutations)RGS5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RGS5 (select a term)
intoGenRGS5
Cancer3DRGS5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM145500    603276   
Orphanet
MedgenRGS5
Genetic Testing Registry RGS5
NextProtO15539 [Medical]
TSGene8490
GENETestsRGS5
Huge Navigator RGS5 [HugePedia]
snp3D : Map Gene to Disease8490
BioCentury BCIQRGS5
ClinGenRGS5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8490
Chemical/Pharm GKB GenePA34376
Clinical trialRGS5
Miscellaneous
canSAR (ICR)RGS5 (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRGS5
EVEXRGS5
GoPubMedRGS5
iHOPRGS5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:24:58 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.