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RNF168 (ring finger protein 168)

Identity

Alias_namesring finger protein 168
Alias_symbol (synonym)FLJ35794
Other aliashRNF168
HGNC (Hugo) RNF168
LocusID (NCBI) 165918
Atlas_Id 50960
Location 3q29  [Link to chromosome band 3q29]
Location_base_pair Starts at 196468786 and ends at 196503768 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RNF168 (3q29) / RNF168 (3q29)RNF168 (3q29) / SCPEP1 (17q22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF168   26661
LRG (Locus Reference Genomic)LRG_185
Cards
Entrez_Gene (NCBI)RNF168  165918  ring finger protein 168
AliaseshRNF168
GeneCards (Weizmann)RNF168
Ensembl hg19 (Hinxton)ENSG00000163961 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163961 [Gene_View]  chr3:196468786-196503768 [Contig_View]  RNF168 [Vega]
ICGC DataPortalENSG00000163961
TCGA cBioPortalRNF168
AceView (NCBI)RNF168
Genatlas (Paris)RNF168
WikiGenes165918
SOURCE (Princeton)RNF168
Genetics Home Reference (NIH)RNF168
Genomic and cartography
GoldenPath hg38 (UCSC)RNF168  -     chr3:196468786-196503768 -  3q29   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF168  -     3q29   [Description]    (hg19-Feb_2009)
EnsemblRNF168 - 3q29 [CytoView hg19]  RNF168 - 3q29 [CytoView hg38]
Mapping of homologs : NCBIRNF168 [Mapview hg19]  RNF168 [Mapview hg38]
OMIM611943   612688   
Gene and transcription
Genbank (Entrez)AK054732 AK093113 AK097068 BC017442 BC029433
RefSeq transcript (Entrez)NM_152617
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF168
Cluster EST : UnigeneHs.250648 [ NCBI ]
CGAP (NCI)Hs.250648
Alternative Splicing GalleryENSG00000163961
Gene ExpressionRNF168 [ NCBI-GEO ]   RNF168 [ EBI - ARRAY_EXPRESS ]   RNF168 [ SEEK ]   RNF168 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF168 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)165918
GTEX Portal (Tissue expression)RNF168
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IYW5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IYW5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IYW5
Splice isoforms : SwissVarQ8IYW5
PhosPhoSitePlusQ8IYW5
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF168
DMDM Disease mutations165918
Blocks (Seattle)RNF168
PDB (SRS)3L11    4GB0   
PDB (PDBSum)3L11    4GB0   
PDB (IMB)3L11    4GB0   
PDB (RSDB)3L11    4GB0   
Structural Biology KnowledgeBase3L11    4GB0   
SCOP (Structural Classification of Proteins)3L11    4GB0   
CATH (Classification of proteins structures)3L11    4GB0   
SuperfamilyQ8IYW5
Human Protein AtlasENSG00000163961
Peptide AtlasQ8IYW5
HPRD08190
IPIIPI00217899   IPI00748121   IPI00925077   
Protein Interaction databases
DIP (DOE-UCLA)Q8IYW5
IntAct (EBI)Q8IYW5
FunCoupENSG00000163961
BioGRIDRNF168
STRING (EMBL)RNF168
ZODIACRNF168
Ontologies - Pathways
QuickGOQ8IYW5
Ontology : AmiGOubiquitin ligase complex  chromatin binding  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytosol  double-strand break repair  double-strand break repair via nonhomologous end joining  ubiquitin-dependent protein catabolic process  cellular response to DNA damage stimulus  zinc ion binding  response to ionizing radiation  protein ubiquitination  nucleosome binding  negative regulation of transcription elongation from RNA polymerase II promoter  histone H2A monoubiquitination  histone H2A monoubiquitination  site of double-strand break  interstrand cross-link repair  histone H2A-K13 ubiquitination  histone H2A-K15 ubiquitination  histone H2A-K15 ubiquitination  histone binding  histone binding  ubiquitin binding  protein complex  isotype switching  positive regulation of DNA repair  positive regulation of DNA repair  K63-linked polyubiquitin binding  protein K63-linked ubiquitination  histone H2A K63-linked ubiquitination  histone H2A K63-linked ubiquitination  
Ontology : EGO-EBIubiquitin ligase complex  chromatin binding  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytosol  double-strand break repair  double-strand break repair via nonhomologous end joining  ubiquitin-dependent protein catabolic process  cellular response to DNA damage stimulus  zinc ion binding  response to ionizing radiation  protein ubiquitination  nucleosome binding  negative regulation of transcription elongation from RNA polymerase II promoter  histone H2A monoubiquitination  histone H2A monoubiquitination  site of double-strand break  interstrand cross-link repair  histone H2A-K13 ubiquitination  histone H2A-K15 ubiquitination  histone H2A-K15 ubiquitination  histone binding  histone binding  ubiquitin binding  protein complex  isotype switching  positive regulation of DNA repair  positive regulation of DNA repair  K63-linked polyubiquitin binding  protein K63-linked ubiquitination  histone H2A K63-linked ubiquitination  histone H2A K63-linked ubiquitination  
NDEx NetworkRNF168
Atlas of Cancer Signalling NetworkRNF168
Wikipedia pathwaysRNF168
Orthology - Evolution
OrthoDB165918
GeneTree (enSembl)ENSG00000163961
Phylogenetic Trees/Animal Genes : TreeFamRNF168
HOVERGENQ8IYW5
HOGENOMQ8IYW5
Homologs : HomoloGeneRNF168
Homology/Alignments : Family Browser (UCSC)RNF168
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF168 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF168
dbVarRNF168
ClinVarRNF168
1000_GenomesRNF168 
Exome Variant ServerRNF168
ExAC (Exome Aggregation Consortium)RNF168 (select the gene name)
Genetic variants : HAPMAP165918
Genomic Variants (DGV)RNF168 [DGVbeta]
DECIPHERRNF168 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF168 
Mutations
ICGC Data PortalRNF168 
TCGA Data PortalRNF168 
Broad Tumor PortalRNF168
OASIS PortalRNF168 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF168  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF168
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch RNF168
DgiDB (Drug Gene Interaction Database)RNF168
DoCM (Curated mutations)RNF168 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF168 (select a term)
intoGenRNF168
Cancer3DRNF168(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611943    612688   
Orphanet23123   
MedgenRNF168
Genetic Testing Registry RNF168
NextProtQ8IYW5 [Medical]
TSGene165918
GENETestsRNF168
Huge Navigator RNF168 [HugePedia]
snp3D : Map Gene to Disease165918
BioCentury BCIQRNF168
ClinGenRNF168
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD165918
Chemical/Pharm GKB GenePA134945219
Clinical trialRNF168
Miscellaneous
canSAR (ICR)RNF168 (select the gene name)
Probes
Litterature
PubMed59 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF168
EVEXRNF168
GoPubMedRNF168
iHOPRNF168
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:35:15 CEST 2017

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