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RNF34 (ring finger protein 34)

Identity

Alias_namesring finger protein 34
Alias_symbol (synonym)RIFF
FLJ21786
RIF
Other aliasCARP-1
CARP1
RFI
hRFI
HGNC (Hugo) RNF34
LocusID (NCBI) 80196
Atlas_Id 42136
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 121400083 and ends at 121424352 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PDE3A (12p12.2) / RNF34 (12q24.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF34   17297
Cards
Entrez_Gene (NCBI)RNF34  80196  ring finger protein 34
AliasesCARP-1; CARP1; RFI; RIF; 
RIFF; hRFI
GeneCards (Weizmann)RNF34
Ensembl hg19 (Hinxton)ENSG00000170633 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170633 [Gene_View]  chr12:121400083-121424352 [Contig_View]  RNF34 [Vega]
ICGC DataPortalENSG00000170633
TCGA cBioPortalRNF34
AceView (NCBI)RNF34
Genatlas (Paris)RNF34
WikiGenes80196
SOURCE (Princeton)RNF34
Genetics Home Reference (NIH)RNF34
Genomic and cartography
GoldenPath hg38 (UCSC)RNF34  -     chr12:121400083-121424352 +  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF34  -     12q24.31   [Description]    (hg19-Feb_2009)
EnsemblRNF34 - 12q24.31 [CytoView hg19]  RNF34 - 12q24.31 [CytoView hg38]
Mapping of homologs : NCBIRNF34 [Mapview hg19]  RNF34 [Mapview hg38]
OMIM608299   
Gene and transcription
Genbank (Entrez)AB084914 AF306709 AK024957 AK025439 AK096994
RefSeq transcript (Entrez)NM_001256858 NM_025126 NM_194271
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF34
Cluster EST : UnigeneHs.292804 [ NCBI ]
CGAP (NCI)Hs.292804
Alternative Splicing GalleryENSG00000170633
Gene ExpressionRNF34 [ NCBI-GEO ]   RNF34 [ EBI - ARRAY_EXPRESS ]   RNF34 [ SEEK ]   RNF34 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF34 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80196
GTEX Portal (Tissue expression)RNF34
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969K3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969K3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969K3
Splice isoforms : SwissVarQ969K3
PhosPhoSitePlusQ969K3
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_FYVE_PHD    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF34
DMDM Disease mutations80196
Blocks (Seattle)RNF34
SuperfamilyQ969K3
Human Protein AtlasENSG00000170633
Peptide AtlasQ969K3
HPRD10509
IPIIPI00100010   IPI00375563   IPI00789888   IPI01024890   IPI01024737   IPI01025257   IPI01025486   IPI01025102   
Protein Interaction databases
DIP (DOE-UCLA)Q969K3
IntAct (EBI)Q969K3
FunCoupENSG00000170633
BioGRIDRNF34
STRING (EMBL)RNF34
ZODIACRNF34
Ontologies - Pathways
QuickGOQ969K3
Ontology : AmiGOp53 binding  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  cytosol  plasma membrane  apoptotic process  zinc ion binding  endomembrane system  protein ubiquitination  protein ubiquitination  nuclear body  nuclear speck  ubiquitin protein ligase binding  nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  ubiquitin protein ligase activity  ubiquitin protein ligase activity  ubiquitin protein ligase activity  cellular response to cold  protein K48-linked ubiquitination  negative regulation of signal transduction by p53 class mediator  phosphatidylinositol phosphate binding  negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  regulation of oxygen metabolic process  negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis  
Ontology : EGO-EBIp53 binding  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  cytosol  plasma membrane  apoptotic process  zinc ion binding  endomembrane system  protein ubiquitination  protein ubiquitination  nuclear body  nuclear speck  ubiquitin protein ligase binding  nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  ubiquitin protein ligase activity  ubiquitin protein ligase activity  ubiquitin protein ligase activity  cellular response to cold  protein K48-linked ubiquitination  negative regulation of signal transduction by p53 class mediator  phosphatidylinositol phosphate binding  negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  regulation of oxygen metabolic process  negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis  
NDEx NetworkRNF34
Atlas of Cancer Signalling NetworkRNF34
Wikipedia pathwaysRNF34
Orthology - Evolution
OrthoDB80196
GeneTree (enSembl)ENSG00000170633
Phylogenetic Trees/Animal Genes : TreeFamRNF34
HOVERGENQ969K3
HOGENOMQ969K3
Homologs : HomoloGeneRNF34
Homology/Alignments : Family Browser (UCSC)RNF34
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF34 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF34
dbVarRNF34
ClinVarRNF34
1000_GenomesRNF34 
Exome Variant ServerRNF34
ExAC (Exome Aggregation Consortium)RNF34 (select the gene name)
Genetic variants : HAPMAP80196
Genomic Variants (DGV)RNF34 [DGVbeta]
DECIPHERRNF34 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF34 
Mutations
ICGC Data PortalRNF34 
TCGA Data PortalRNF34 
Broad Tumor PortalRNF34
OASIS PortalRNF34 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF34  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF34
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF34
DgiDB (Drug Gene Interaction Database)RNF34
DoCM (Curated mutations)RNF34 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF34 (select a term)
intoGenRNF34
Cancer3DRNF34(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608299   
Orphanet
MedgenRNF34
Genetic Testing Registry RNF34
NextProtQ969K3 [Medical]
TSGene80196
GENETestsRNF34
Huge Navigator RNF34 [HugePedia]
snp3D : Map Gene to Disease80196
BioCentury BCIQRNF34
ClinGenRNF34
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80196
Chemical/Pharm GKB GenePA34436
Clinical trialRNF34
Miscellaneous
canSAR (ICR)RNF34 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF34
EVEXRNF34
GoPubMedRNF34
iHOPRNF34
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:35:20 CEST 2017

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