Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RNF5 (ring finger protein 5)

Identity

Alias_namesring finger protein 5
Alias_symbol (synonym)NG2
G16
RING5
RMA1
Other alias
HGNC (Hugo) RNF5
LocusID (NCBI) 6048
Atlas_Id 46748
Location 6p21.32  [Link to chromosome band 6p21]
Location_base_pair Starts at 32178385 and ends at 32180793 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF5   10068
Cards
Entrez_Gene (NCBI)RNF5  6048  ring finger protein 5
AliasesRING5; RMA1
GeneCards (Weizmann)RNF5
Ensembl hg19 (Hinxton)ENSG00000204308 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204308 [Gene_View]  ENSG00000204308 [Sequence]  chr6:32178385-32180793 [Contig_View]  RNF5 [Vega]
ICGC DataPortalENSG00000204308
TCGA cBioPortalRNF5
AceView (NCBI)RNF5
Genatlas (Paris)RNF5
WikiGenes6048
SOURCE (Princeton)RNF5
Genetics Home Reference (NIH)RNF5
Genomic and cartography
GoldenPath hg38 (UCSC)RNF5  -     chr6:32178385-32180793 +  6p21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF5  -     6p21.32   [Description]    (hg19-Feb_2009)
EnsemblRNF5 - 6p21.32 [CytoView hg19]  RNF5 - 6p21.32 [CytoView hg38]
Mapping of homologs : NCBIRNF5 [Mapview hg19]  RNF5 [Mapview hg38]
OMIM602677   
Gene and transcription
Genbank (Entrez)AB056869 AJ243936 AK296212 AK311221 AK311859
RefSeq transcript (Entrez)NM_006913
RefSeq genomic (Entrez)NC_000006 NT_113891 NT_167244 NT_167246 NT_167247 NT_167248 NT_167249
Consensus coding sequences : CCDS (NCBI)RNF5
Cluster EST : UnigeneHs.731774 [ NCBI ]
CGAP (NCI)Hs.731774
Alternative Splicing GalleryENSG00000204308
Gene ExpressionRNF5 [ NCBI-GEO ]   RNF5 [ EBI - ARRAY_EXPRESS ]   RNF5 [ SEEK ]   RNF5 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6048
GTEX Portal (Tissue expression)RNF5
Human Protein AtlasENSG00000204308-RNF5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99942   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99942  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99942
Splice isoforms : SwissVarQ99942
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ99942
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF5
DMDM Disease mutations6048
Blocks (Seattle)RNF5
SuperfamilyQ99942
Human Protein Atlas [tissue]ENSG00000204308-RNF5 [tissue]
Peptide AtlasQ99942
HPRD04057
IPIIPI00012608   IPI00514241   IPI00742773   IPI00910392   
Protein Interaction databases
DIP (DOE-UCLA)Q99942
IntAct (EBI)Q99942
FunCoupENSG00000204308
BioGRIDRNF5
STRING (EMBL)RNF5
ZODIACRNF5
Ontologies - Pathways
QuickGOQ99942
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  ubiquitin-dependent protein catabolic process  zinc ion binding  response to bacterium  negative regulation of autophagy  integral component of membrane  ubiquitin-dependent ERAD pathway  protein destabilization  mitochondrial membrane  ERAD pathway  Derlin-1 retrotranslocation complex  Derlin-1 retrotranslocation complex  identical protein binding  cellular protein catabolic process  endoplasmic reticulum quality control compartment  ubiquitin-like protein conjugating enzyme binding  transmembrane transport  ubiquitin protein ligase activity  ubiquitin protein ligase activity  protein K63-linked ubiquitination  protein K48-linked ubiquitination  ER-associated misfolded protein catabolic process  ER-associated misfolded protein catabolic process  endoplasmic reticulum mannose trimming  regulation of autophagosome assembly  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  ubiquitin-dependent protein catabolic process  zinc ion binding  response to bacterium  negative regulation of autophagy  integral component of membrane  ubiquitin-dependent ERAD pathway  protein destabilization  mitochondrial membrane  ERAD pathway  Derlin-1 retrotranslocation complex  Derlin-1 retrotranslocation complex  identical protein binding  cellular protein catabolic process  endoplasmic reticulum quality control compartment  ubiquitin-like protein conjugating enzyme binding  transmembrane transport  ubiquitin protein ligase activity  ubiquitin protein ligase activity  protein K63-linked ubiquitination  protein K48-linked ubiquitination  ER-associated misfolded protein catabolic process  ER-associated misfolded protein catabolic process  endoplasmic reticulum mannose trimming  regulation of autophagosome assembly  
Pathways : KEGGProtein processing in endoplasmic reticulum   
NDEx NetworkRNF5
Atlas of Cancer Signalling NetworkRNF5
Wikipedia pathwaysRNF5
Orthology - Evolution
OrthoDB6048
GeneTree (enSembl)ENSG00000204308
Phylogenetic Trees/Animal Genes : TreeFamRNF5
HOVERGENQ99942
HOGENOMQ99942
Homologs : HomoloGeneRNF5
Homology/Alignments : Family Browser (UCSC)RNF5
Gene fusions - Rearrangements
Fusion : QuiverRNF5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF5
dbVarRNF5
ClinVarRNF5
1000_GenomesRNF5 
Exome Variant ServerRNF5
ExAC (Exome Aggregation Consortium)ENSG00000204308
GNOMAD BrowserENSG00000204308
Varsome BrowserRNF5
Genetic variants : HAPMAP6048
Genomic Variants (DGV)RNF5 [DGVbeta]
DECIPHERRNF5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF5 
Mutations
ICGC Data PortalRNF5 
TCGA Data PortalRNF5 
Broad Tumor PortalRNF5
OASIS PortalRNF5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF5
DgiDB (Drug Gene Interaction Database)RNF5
DoCM (Curated mutations)RNF5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF5 (select a term)
intoGenRNF5
Cancer3DRNF5(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602677   
Orphanet
DisGeNETRNF5
MedgenRNF5
Genetic Testing Registry RNF5
NextProtQ99942 [Medical]
TSGene6048
GENETestsRNF5
Target ValidationRNF5
Huge Navigator RNF5 [HugePedia]
snp3D : Map Gene to Disease6048
BioCentury BCIQRNF5
ClinGenRNF5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6048
Chemical/Pharm GKB GenePA34442
Clinical trialRNF5
Miscellaneous
canSAR (ICR)RNF5 (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF5
EVEXRNF5
GoPubMedRNF5
iHOPRNF5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:36:08 CET 2018

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