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RRAS (related RAS viral (r-ras) oncogene homolog)

Identity

Other names-
HGNC (Hugo) RRAS
LocusID (NCBI) 6237
Location 19q13.33
Location_base_pair Starts at 50138552 and ends at 50143400 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RRAS   10447
Cards
Entrez_Gene (NCBI)RRAS  6237  related RAS viral (r-ras) oncogene homolog
GeneCards (Weizmann)RRAS
Ensembl hg19 (Hinxton)ENSG00000126458 [Gene_View]  chr19:50138552-50143400 [Contig_View]  RRAS [Vega]
Ensembl hg38 (Hinxton)ENSG00000126458 [Gene_View]  chr19:50138552-50143400 [Contig_View]  RRAS [Vega]
ICGC DataPortalENSG00000126458
cBioPortalRRAS
AceView (NCBI)RRAS
Genatlas (Paris)RRAS
WikiGenes6237
SOURCE (Princeton)RRAS
Genomic and cartography
GoldenPath hg19 (UCSC)RRAS  -     chr19:50138552-50143400 -  19q13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RRAS  -     19q13.33   [Description]    (hg38-Dec_2013)
EnsemblRRAS - 19q13.33 [CytoView hg19]  RRAS - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBIRRAS [Mapview hg19]  RRAS [Mapview hg38]
OMIM165090   
Gene and transcription
Genbank (Entrez)AF493920 BC016286 BC016318 BT006805 CR541944
RefSeq transcript (Entrez)NM_006270
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NT_011109 NW_001838497 NW_004929415
Consensus coding sequences : CCDS (NCBI)RRAS
Cluster EST : UnigeneHs.515536 [ NCBI ]
CGAP (NCI)Hs.515536
Alternative Splicing : Fast-db (Paris)GSHG0016004
Alternative Splicing GalleryENSG00000126458
Gene ExpressionRRAS [ NCBI-GEO ]     RRAS [ SEEK ]   RRAS [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP10301 (Uniprot)
NextProtP10301  [Medical]
With graphics : InterProP10301
Splice isoforms : SwissVarP10301 (Swissvar)
Domaine pattern : Prosite (Expaxy)RAS (PS51421)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Ras   
Related proteins : CluSTrP10301
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Domain families : Smart (EMBL)RAS (SM00173)  
DMDM Disease mutations6237
Blocks (Seattle)P10301
PDB (SRS)2FN4   
PDB (PDBSum)2FN4   
PDB (IMB)2FN4   
PDB (RSDB)2FN4   
Human Protein AtlasENSG00000126458
Peptide AtlasP10301
HPRD01299
IPIIPI00020418   
Protein Interaction databases
DIP (DOE-UCLA)P10301
IntAct (EBI)P10301
FunCoupENSG00000126458
BioGRIDRRAS
IntegromeDBRRAS
STRING (EMBL)RRAS
Ontologies - Pathways
QuickGOP10301
Ontology : AmiGOGTPase activity  protein binding  GTP binding  plasma membrane  GTP catabolic process  Ras protein signal transduction  synaptic transmission  axon guidance  GDP binding  negative regulation of cell migration  protein complex binding  positive regulation of angiogenesis  extracellular vesicular exosome  
Ontology : EGO-EBIGTPase activity  protein binding  GTP binding  plasma membrane  GTP catabolic process  Ras protein signal transduction  synaptic transmission  axon guidance  GDP binding  negative regulation of cell migration  protein complex binding  positive regulation of angiogenesis  extracellular vesicular exosome  
Pathways : KEGGMAPK signaling pathway    Ras signaling pathway    Rap1 signaling pathway    Tight junction    Regulation of actin cytoskeleton    HTLV-I infection    Proteoglycans in cancer   
Protein Interaction DatabaseRRAS
DoCM (Curated mutations)RRAS
Wikipedia pathwaysRRAS
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerRRAS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RRAS
dbVarRRAS
ClinVarRRAS
1000_GenomesRRAS 
Exome Variant ServerRRAS
SNP (GeneSNP Utah)RRAS
SNP : HGBaseRRAS
Genetic variants : HAPMAPRRAS
Genomic VariantsRRAS  RRAS [DGVbeta]
Mutations
ICGC Data PortalENSG00000126458 
Somatic Mutations in Cancer : COSMICRRAS 
CONAN: Copy Number AnalysisRRAS 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)19:50138552-50143400
Mutations and Diseases : HGMDRRAS
OMIM165090   
MedgenRRAS
NextProtP10301 [Medical]
GENETestsRRAS
Disease Genetic AssociationRRAS
Huge Navigator RRAS [HugePedia]  RRAS [HugeCancerGEM]
snp3D : Map Gene to Disease6237
DGIdb (Drug Gene Interaction db)RRAS
General knowledge
Homologs : HomoloGeneRRAS
Homology/Alignments : Family Browser (UCSC)RRAS
Phylogenetic Trees/Animal Genes : TreeFamRRAS
Chemical/Protein Interactions : CTD6237
Chemical/Pharm GKB GenePA34861
Clinical trialRRAS
Cancer Resource (Charite)ENSG00000126458
Other databases
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
CoreMineRRAS
GoPubMedRRAS
iHOPRRAS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 01:16:11 CET 2014

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