Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

RTN4IP1 (reticulon 4 interacting protein 1)

Identity

Alias_symbol (synonym)NIMP
Other aliasOPA10
HGNC (Hugo) RTN4IP1
LocusID (NCBI) 84816
Atlas_Id 53304
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 106570771 and ends at 106629498 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CTDSP2 (12q14.1) / RTN4IP1 (6q21)CTDSP2 12q14.1 / RTN4IP1 6q21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;12)(q21;q14) CTDSP2/RTN4IP1


External links

Nomenclature
HGNC (Hugo)RTN4IP1   18647
Cards
Entrez_Gene (NCBI)RTN4IP1  84816  reticulon 4 interacting protein 1
AliasesNIMP; OPA10
GeneCards (Weizmann)RTN4IP1
Ensembl hg19 (Hinxton)ENSG00000130347 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130347 [Gene_View]  ENSG00000130347 [Sequence]  chr6:106570771-106629498 [Contig_View]  RTN4IP1 [Vega]
ICGC DataPortalENSG00000130347
TCGA cBioPortalRTN4IP1
AceView (NCBI)RTN4IP1
Genatlas (Paris)RTN4IP1
WikiGenes84816
SOURCE (Princeton)RTN4IP1
Genetics Home Reference (NIH)RTN4IP1
Genomic and cartography
GoldenPath hg38 (UCSC)RTN4IP1  -     chr6:106570771-106629498 -  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RTN4IP1  -     6q21   [Description]    (hg19-Feb_2009)
EnsemblRTN4IP1 - 6q21 [CytoView hg19]  RTN4IP1 - 6q21 [CytoView hg38]
Mapping of homologs : NCBIRTN4IP1 [Mapview hg19]  RTN4IP1 [Mapview hg38]
OMIM610502   616732   
Gene and transcription
Genbank (Entrez)AF336861 AF439711 AK095207 AK313962 AY063761
RefSeq transcript (Entrez)NM_001318746 NM_032730
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RTN4IP1
Cluster EST : UnigeneHs.155839 [ NCBI ]
CGAP (NCI)Hs.155839
Alternative Splicing GalleryENSG00000130347
Gene ExpressionRTN4IP1 [ NCBI-GEO ]   RTN4IP1 [ EBI - ARRAY_EXPRESS ]   RTN4IP1 [ SEEK ]   RTN4IP1 [ MEM ]
Gene Expression Viewer (FireBrowse)RTN4IP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84816
GTEX Portal (Tissue expression)RTN4IP1
Human Protein AtlasENSG00000130347-RTN4IP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WWV3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WWV3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WWV3
Splice isoforms : SwissVarQ8WWV3
PhosPhoSitePlusQ8WWV3
Domaine pattern : Prosite (Expaxy)QOR_ZETA_CRYSTAL (PS01162)   
Domains : Interpro (EBI)ADH_N    GroES-like    NAD(P)-bd_dom    PKS_ER    Quin_OxRdtase/zeta-crystal_CS   
Domain families : Pfam (Sanger)ADH_N (PF08240)   
Domain families : Pfam (NCBI)pfam08240   
Domain families : Smart (EMBL)PKS_ER (SM00829)  
Conserved Domain (NCBI)RTN4IP1
DMDM Disease mutations84816
Blocks (Seattle)RTN4IP1
PDB (SRS)2VN8   
PDB (PDBSum)2VN8   
PDB (IMB)2VN8   
PDB (RSDB)2VN8   
Structural Biology KnowledgeBase2VN8   
SCOP (Structural Classification of Proteins)2VN8   
CATH (Classification of proteins structures)2VN8   
SuperfamilyQ8WWV3
Human Protein Atlas [tissue]ENSG00000130347-RTN4IP1 [tissue]
Peptide AtlasQ8WWV3
HPRD18008
IPIIPI00291972   IPI00383312   IPI00641912   IPI00651757   
Protein Interaction databases
DIP (DOE-UCLA)Q8WWV3
IntAct (EBI)Q8WWV3
FunCoupENSG00000130347
BioGRIDRTN4IP1
STRING (EMBL)RTN4IP1
ZODIACRTN4IP1
Ontologies - Pathways
QuickGOQ8WWV3
Ontology : AmiGOmitochondrial outer membrane  nervous system development  zinc ion binding  oxidoreductase activity  regulation of dendrite development  oxidation-reduction process  
Ontology : EGO-EBImitochondrial outer membrane  nervous system development  zinc ion binding  oxidoreductase activity  regulation of dendrite development  oxidation-reduction process  
NDEx NetworkRTN4IP1
Atlas of Cancer Signalling NetworkRTN4IP1
Wikipedia pathwaysRTN4IP1
Orthology - Evolution
OrthoDB84816
GeneTree (enSembl)ENSG00000130347
Phylogenetic Trees/Animal Genes : TreeFamRTN4IP1
HOVERGENQ8WWV3
HOGENOMQ8WWV3
Homologs : HomoloGeneRTN4IP1
Homology/Alignments : Family Browser (UCSC)RTN4IP1
Gene fusions - Rearrangements
Fusion : MitelmanCTDSP2/RTN4IP1 [12q14.1/6q21]  [t(6;12)(q21;q14)]  
Fusion PortalCTDSP2 12q14.1 RTN4IP1 6q21 LUAD
Fusion : QuiverRTN4IP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRTN4IP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RTN4IP1
dbVarRTN4IP1
ClinVarRTN4IP1
1000_GenomesRTN4IP1 
Exome Variant ServerRTN4IP1
ExAC (Exome Aggregation Consortium)ENSG00000130347
GNOMAD BrowserENSG00000130347
Genetic variants : HAPMAP84816
Genomic Variants (DGV)RTN4IP1 [DGVbeta]
DECIPHERRTN4IP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRTN4IP1 
Mutations
ICGC Data PortalRTN4IP1 
TCGA Data PortalRTN4IP1 
Broad Tumor PortalRTN4IP1
OASIS PortalRTN4IP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRTN4IP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRTN4IP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch RTN4IP1
DgiDB (Drug Gene Interaction Database)RTN4IP1
DoCM (Curated mutations)RTN4IP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RTN4IP1 (select a term)
intoGenRTN4IP1
Cancer3DRTN4IP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610502    616732   
Orphanet
DisGeNETRTN4IP1
MedgenRTN4IP1
Genetic Testing Registry RTN4IP1
NextProtQ8WWV3 [Medical]
TSGene84816
GENETestsRTN4IP1
Target ValidationRTN4IP1
Huge Navigator RTN4IP1 [HugePedia]
snp3D : Map Gene to Disease84816
BioCentury BCIQRTN4IP1
ClinGenRTN4IP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84816
Chemical/Pharm GKB GenePA38619
Clinical trialRTN4IP1
Miscellaneous
canSAR (ICR)RTN4IP1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRTN4IP1
EVEXRTN4IP1
GoPubMedRTN4IP1
iHOPRTN4IP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:48:07 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.