RTN4IP1 (reticulon 4 interacting protein 1)

2013-05-01  

Identity

HGNC
LOCATION
6q21
LOCUSID
ALIAS
NIMP,OPA10
FUSION GENES

Other Information

Locus ID:

NCBI: 84816
MIM: 610502
HGNC: 18647
Ensembl: ENSG00000130347

Variants:

dbSNP: 84816
ClinVar: 84816
TCGA: ENSG00000130347
COSMIC: RTN4IP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130347ENST00000369063Q8WWV3
ENSG00000130347ENST00000539449G3V1R2

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
362311152022A Novel Homozygous Founder Variant of RTN4IP1 in Two Consanguineous Saudi Families.0
362311152022A Novel Homozygous Founder Variant of RTN4IP1 in Two Consanguineous Saudi Families.0
330377792021Exome sequencing identifies novel missense and deletion variants in RTN4IP1 associated with optic atrophy, global developmental delay, epilepsy, ataxia, and choreoathetosis.4
331366662021Combined Optic Atrophy and Rod-Cone Dystrophy Expands the RTN4IP1 (Optic Atrophy 10) Phenotype.6
333158312021A ROD-CONE DYSTROPHY IS SYSTEMATICALLY ASSOCIATED TO THE RTN4IP1 RECESSIVE OPTIC ATROPHY.3
330377792021Exome sequencing identifies novel missense and deletion variants in RTN4IP1 associated with optic atrophy, global developmental delay, epilepsy, ataxia, and choreoathetosis.4
331366662021Combined Optic Atrophy and Rod-Cone Dystrophy Expands the RTN4IP1 (Optic Atrophy 10) Phenotype.6
333158312021A ROD-CONE DYSTROPHY IS SYSTEMATICALLY ASSOCIATED TO THE RTN4IP1 RECESSIVE OPTIC ATROPHY.3
291815102018Neurologic Phenotypes Associated With Mutations in RTN4IP1 (OPA10) in Children and Young Adults.17
291815102018Neurologic Phenotypes Associated With Mutations in RTN4IP1 (OPA10) in Children and Young Adults.17
265932672015Recessive Mutations in RTN4IP1 Cause Isolated and Syndromic Optic Neuropathies.28
265932672015Recessive Mutations in RTN4IP1 Cause Isolated and Syndromic Optic Neuropathies.28
233931702013RTN4IP1 is down-regulated in thyroid cancer and has tumor-suppressive function.8
233931702013RTN4IP1 is down-regulated in thyroid cancer and has tumor-suppressive function.8
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

RTN4IP1 (reticulon 4 interacting protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53304/rtn4ip1