Atlas of Genetics and Cytogenetics in Oncology and Haematology

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RXRG (retinoid X receptor gamma)

Identity

Alias (NCBI)NR2B3
RXRC
HGNC (Hugo) RXRG
HGNC Alias symbNR2B3
HGNC Alias namenuclear receptor subfamily 2 group B member 3
HGNC Previous nameretinoid X receptor, gamma
LocusID (NCBI) 6258
Atlas_Id 42188
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 165400922 and ends at 165445126 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EPB41L2 (6q23.1) / RXRG (1q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RXRG   10479
Cards
Entrez_Gene (NCBI)RXRG    retinoid X receptor gamma
AliasesNR2B3; RXRC
GeneCards (Weizmann)RXRG
Ensembl hg19 (Hinxton)ENSG00000143171 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143171 [Gene_View]  ENSG00000143171 [Sequence]  chr1:165400922-165445126 [Contig_View]  RXRG [Vega]
ICGC DataPortalENSG00000143171
TCGA cBioPortalRXRG
AceView (NCBI)RXRG
Genatlas (Paris)RXRG
SOURCE (Princeton)RXRG
Genetics Home Reference (NIH)RXRG
Genomic and cartography
GoldenPath hg38 (UCSC)RXRG  -     chr1:165400922-165445126 -  1q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RXRG  -     1q23.3   [Description]    (hg19-Feb_2009)
GoldenPathRXRG - 1q23.3 [CytoView hg19]  RXRG - 1q23.3 [CytoView hg38]
ImmunoBaseENSG00000143171
genome Data Viewer NCBIRXRG [Mapview hg19]  
OMIM180247   
Gene and transcription
Genbank (Entrez)AB307706 AB593015 AB593016 AK125497 AK312922
RefSeq transcript (Entrez)NM_001256570 NM_001256571 NM_006917
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RXRG
Alternative Splicing GalleryENSG00000143171
Gene ExpressionRXRG [ NCBI-GEO ]   RXRG [ EBI - ARRAY_EXPRESS ]   RXRG [ SEEK ]   RXRG [ MEM ]
Gene Expression Viewer (FireBrowse)RXRG [ Firebrowse - Broad ]
GenevisibleExpression of RXRG in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6258
GTEX Portal (Tissue expression)RXRG
Human Protein AtlasENSG00000143171-RXRG [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48443   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP48443  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48443
Splice isoforms : SwissVarP48443
PhosPhoSitePlusP48443
Domaine pattern : Prosite (Expaxy)NR_LBD (PS51843)    NUCLEAR_REC_DBD_1 (PS00031)    NUCLEAR_REC_DBD_2 (PS51030)   
Domains : Interpro (EBI)NHR-like_dom_sf    Nuc_recep-AF1    Nucl_hrmn_rcpt_lig-bd    Nuclear_hrmn_rcpt    Retinoid-X_rcpt/HNF4    Znf_hrmn_rcpt    Znf_NHR/GATA   
Domain families : Pfam (Sanger)Hormone_recep (PF00104)    Nuc_recep-AF1 (PF11825)    zf-C4 (PF00105)   
Domain families : Pfam (NCBI)pfam00104    pfam11825    pfam00105   
Domain families : Smart (EMBL)HOLI (SM00430)  ZnF_C4 (SM00399)  
Conserved Domain (NCBI)RXRG
Blocks (Seattle)RXRG
PDB (RSDB)2GL8   
PDB Europe2GL8   
PDB (PDBSum)2GL8   
PDB (IMB)2GL8   
Structural Biology KnowledgeBase2GL8   
SCOP (Structural Classification of Proteins)2GL8   
CATH (Classification of proteins structures)2GL8   
SuperfamilyP48443
Human Protein Atlas [tissue]ENSG00000143171-RXRG [tissue]
Peptide AtlasP48443
HPRD01579
IPIIPI00009736   IPI00982797   
Protein Interaction databases
DIP (DOE-UCLA)P48443
IntAct (EBI)P48443
BioGRIDRXRG
STRING (EMBL)RXRG
ZODIACRXRG
Ontologies - Pathways
QuickGOP48443
Ontology : AmiGOnuclear chromatin  RNA polymerase II regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  steroid hormone receptor activity  nuclear receptor activity  protein binding  nucleus  nucleoplasm  cytoplasm  regulation of transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  zinc ion binding  cell differentiation  response to retinoic acid  host cell nucleus  steroid hormone mediated signaling pathway  retinoic acid-responsive element binding  positive regulation of transcription by RNA polymerase II  retinoic acid receptor signaling pathway  anatomical structure development  RNA polymerase II transcription factor complex  
Ontology : EGO-EBInuclear chromatin  RNA polymerase II regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  steroid hormone receptor activity  nuclear receptor activity  protein binding  nucleus  nucleoplasm  cytoplasm  regulation of transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  zinc ion binding  cell differentiation  response to retinoic acid  host cell nucleus  steroid hormone mediated signaling pathway  retinoic acid-responsive element binding  positive regulation of transcription by RNA polymerase II  retinoic acid receptor signaling pathway  anatomical structure development  RNA polymerase II transcription factor complex  
Pathways : KEGGPPAR signaling pathway    Thyroid hormone signaling pathway    Adipocytokine signaling pathway    Pathways in cancer    Transcriptional misregulation in cancer    Thyroid cancer    Small cell lung cancer    Non-small cell lung cancer   
NDEx NetworkRXRG
Atlas of Cancer Signalling NetworkRXRG
Wikipedia pathwaysRXRG
Orthology - Evolution
OrthoDB6258
GeneTree (enSembl)ENSG00000143171
Phylogenetic Trees/Animal Genes : TreeFamRXRG
HOGENOMP48443
Homologs : HomoloGeneRXRG
Homology/Alignments : Family Browser (UCSC)RXRG
Gene fusions - Rearrangements
Fusion : QuiverRXRG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRXRG [hg38]
dbVarRXRG
ClinVarRXRG
MonarchRXRG
1000_GenomesRXRG 
Exome Variant ServerRXRG
GNOMAD BrowserENSG00000143171
Varsome BrowserRXRG
Genomic Variants (DGV)RXRG [DGVbeta]
DECIPHERRXRG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRXRG 
Mutations
ICGC Data PortalRXRG 
TCGA Data PortalRXRG 
Broad Tumor PortalRXRG
OASIS PortalRXRG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRXRG  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRXRG
Mutations and Diseases : HGMDRXRG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RXRG
DgiDB (Drug Gene Interaction Database)RXRG
DoCM (Curated mutations)RXRG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RXRG (select a term)
intoGenRXRG
Cancer3DRXRG(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM180247   
Orphanet
DisGeNETRXRG
MedgenRXRG
Genetic Testing Registry RXRG
NextProtP48443 [Medical]
GENETestsRXRG
Target ValidationRXRG
Huge Navigator RXRG [HugePedia]
ClinGenRXRG
Clinical trials, drugs, therapy
MyCancerGenomeRXRG
Protein Interactions : CTD
Pharm GKB GenePA34892
PharosP48443
Clinical trialRXRG
Miscellaneous
canSAR (ICR)RXRG (select the gene name)
HarmonizomeRXRG
DataMed IndexRXRG
Probes
Litterature
PubMed93 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRXRG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Fri Jan 1 18:36:01 CET 2021
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