Atlas of Genetics and Cytogenetics in Oncology and Haematology

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RXRG (retinoid X receptor gamma)

Identity

Alias_namesretinoid X receptor
Alias_symbol (synonym)NR2B3
Other aliasRXRC
HGNC (Hugo) RXRG
LocusID (NCBI) 6258
Atlas_Id 42188
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 165400922 and ends at 165445355 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		EPB41L2 (6q23.1) / RXRG (1q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RXRG   10479
Cards
Entrez_Gene (NCBI)RXRG  6258  retinoid X receptor gamma
AliasesNR2B3; RXRC
GeneCards (Weizmann)RXRG
Ensembl hg19 (Hinxton)ENSG00000143171 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143171 [Gene_View]  chr1:165400922-165445355 [Contig_View]  RXRG [Vega]
ICGC DataPortalENSG00000143171
TCGA cBioPortalRXRG
AceView (NCBI)RXRG
Genatlas (Paris)RXRG
WikiGenes6258
SOURCE (Princeton)RXRG
Genetics Home Reference (NIH)RXRG
Genomic and cartography
GoldenPath hg38 (UCSC)RXRG  -     chr1:165400922-165445355 -  1q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RXRG  -     1q23.3   [Description]    (hg19-Feb_2009)
EnsemblRXRG - 1q23.3 [CytoView hg19]  RXRG - 1q23.3 [CytoView hg38]
Mapping of homologs : NCBIRXRG [Mapview hg19]  RXRG [Mapview hg38]
OMIM180247   
Gene and transcription
Genbank (Entrez)AB307706 AB593015 AB593016 AK125497 AK312922
RefSeq transcript (Entrez)NM_001256570 NM_001256571 NM_006917
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RXRG
Cluster EST : UnigeneHs.26550 [ NCBI ]
CGAP (NCI)Hs.26550
Alternative Splicing GalleryENSG00000143171
Gene ExpressionRXRG [ NCBI-GEO ]   RXRG [ EBI - ARRAY_EXPRESS ]   RXRG [ SEEK ]   RXRG [ MEM ]
Gene Expression Viewer (FireBrowse)RXRG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6258
GTEX Portal (Tissue expression)RXRG
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48443   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP48443  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48443
Splice isoforms : SwissVarP48443
PhosPhoSitePlusP48443
Domaine pattern : Prosite (Expaxy)NUCLEAR_REC_DBD_1 (PS00031)    NUCLEAR_REC_DBD_2 (PS51030)   
Domains : Interpro (EBI)Nuc_recep-AF1    Nucl_hrmn_rcpt_lig-bd    Nuclear_hrmn_rcpt    Retinoid-X_rcpt/HNF4    Znf_hrmn_rcpt    Znf_NHR/GATA   
Domain families : Pfam (Sanger)Hormone_recep (PF00104)    Nuc_recep-AF1 (PF11825)    zf-C4 (PF00105)   
Domain families : Pfam (NCBI)pfam00104    pfam11825    pfam00105   
Domain families : Smart (EMBL)HOLI (SM00430)  ZnF_C4 (SM00399)  
Conserved Domain (NCBI)RXRG
DMDM Disease mutations6258
Blocks (Seattle)RXRG
PDB (SRS)2GL8   
PDB (PDBSum)2GL8   
PDB (IMB)2GL8   
PDB (RSDB)2GL8   
Structural Biology KnowledgeBase2GL8   
SCOP (Structural Classification of Proteins)2GL8   
CATH (Classification of proteins structures)2GL8   
SuperfamilyP48443
Human Protein AtlasENSG00000143171
Peptide AtlasP48443
HPRD01579
IPIIPI00009736   IPI00982797   
Protein Interaction databases
DIP (DOE-UCLA)P48443
IntAct (EBI)P48443
FunCoupENSG00000143171
BioGRIDRXRG
STRING (EMBL)RXRG
ZODIACRXRG
Ontologies - Pathways
QuickGOP48443
Ontology : AmiGORNA polymerase II regulatory region sequence-specific DNA binding  steroid hormone receptor activity  9-cis retinoic acid receptor activity  protein binding  nucleoplasm  transcription initiation from RNA polymerase II promoter  zinc ion binding  steroid hormone mediated signaling pathway  retinoic acid receptor signaling pathway  protein homotetramerization  positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus  
Ontology : EGO-EBIRNA polymerase II regulatory region sequence-specific DNA binding  steroid hormone receptor activity  9-cis retinoic acid receptor activity  protein binding  nucleoplasm  transcription initiation from RNA polymerase II promoter  zinc ion binding  steroid hormone mediated signaling pathway  retinoic acid receptor signaling pathway  protein homotetramerization  positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus  
Pathways : KEGG   
NDEx NetworkRXRG
Atlas of Cancer Signalling NetworkRXRG
Wikipedia pathwaysRXRG
Orthology - Evolution
OrthoDB6258
GeneTree (enSembl)ENSG00000143171
Phylogenetic Trees/Animal Genes : TreeFamRXRG
HOVERGENP48443
HOGENOMP48443
Homologs : HomoloGeneRXRG
Homology/Alignments : Family Browser (UCSC)RXRG
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRXRG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RXRG
dbVarRXRG
ClinVarRXRG
1000_GenomesRXRG 
Exome Variant ServerRXRG
ExAC (Exome Aggregation Consortium)RXRG (select the gene name)
Genetic variants : HAPMAP6258
Genomic Variants (DGV)RXRG [DGVbeta]
DECIPHERRXRG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRXRG 
Mutations
ICGC Data PortalRXRG 
TCGA Data PortalRXRG 
Broad Tumor PortalRXRG
OASIS PortalRXRG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRXRG  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRXRG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RXRG
DgiDB (Drug Gene Interaction Database)RXRG
DoCM (Curated mutations)RXRG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RXRG (select a term)
intoGenRXRG
Cancer3DRXRG(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM180247   
Orphanet
MedgenRXRG
Genetic Testing Registry RXRG
NextProtP48443 [Medical]
TSGene6258
GENETestsRXRG
Target ValidationRXRG
Huge Navigator RXRG [HugePedia]
snp3D : Map Gene to Disease6258
BioCentury BCIQRXRG
ClinGenRXRG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6258
Chemical/Pharm GKB GenePA34892
Clinical trialRXRG
Miscellaneous
canSAR (ICR)RXRG (select the gene name)
Probes
Litterature
PubMed84 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRXRG
EVEXRXRG
GoPubMedRXRG
iHOPRXRG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:54:12 CEST 2017
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