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SCG5 (secretogranin V)

Identity

Alias_namesSGNE1
secretory granule
Alias_symbol (synonym)7B2
SgV
Other aliasP7B2
HGNC (Hugo) SCG5
LocusID (NCBI) 6447
Atlas_Id 49757
Location 15q13.3  [Link to chromosome band 15q13]
Location_base_pair Starts at 32641613 and ends at 32697098 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SCG5 (15q13.3) / HBA2 (16p13.3)SNX1 (15q22.31) / SCG5 (15q13.3)ZNF385B (2q31.2) / SCG5 (15q13.3)
SNX1 15q22.31 / SCG5 15q13.3ZNF385B 2q31.2 / SCG5 15q13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SCG5   10816
Cards
Entrez_Gene (NCBI)SCG5  6447  secretogranin V
Aliases7B2; P7B2; SGNE1; SgV
GeneCards (Weizmann)SCG5
Ensembl hg19 (Hinxton)ENSG00000166922 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166922 [Gene_View]  chr15:32641613-32697098 [Contig_View]  SCG5 [Vega]
ICGC DataPortalENSG00000166922
TCGA cBioPortalSCG5
AceView (NCBI)SCG5
Genatlas (Paris)SCG5
WikiGenes6447
SOURCE (Princeton)SCG5
Genetics Home Reference (NIH)SCG5
Genomic and cartography
GoldenPath hg38 (UCSC)SCG5  -     chr15:32641613-32697098 +  15q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SCG5  -     15q13.3   [Description]    (hg19-Feb_2009)
EnsemblSCG5 - 15q13.3 [CytoView hg19]  SCG5 - 15q13.3 [CytoView hg38]
Mapping of homologs : NCBISCG5 [Mapview hg19]  SCG5 [Mapview hg38]
OMIM173120   
Gene and transcription
Genbank (Entrez)AK314965 BC005349 BC093053 BP308267 BP377248
RefSeq transcript (Entrez)NM_001144757 NM_003020
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_051230 NT_187660 NW_011332701 NW_012132920
Consensus coding sequences : CCDS (NCBI)SCG5
Cluster EST : UnigeneHs.156540 [ NCBI ]
CGAP (NCI)Hs.156540
Alternative Splicing GalleryENSG00000166922
Gene ExpressionSCG5 [ NCBI-GEO ]   SCG5 [ EBI - ARRAY_EXPRESS ]   SCG5 [ SEEK ]   SCG5 [ MEM ]
Gene Expression Viewer (FireBrowse)SCG5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6447
GTEX Portal (Tissue expression)SCG5
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05408   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05408  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05408
Splice isoforms : SwissVarP05408
PhosPhoSitePlusP05408
Domains : Interpro (EBI)Secretogranin_V   
Domain families : Pfam (Sanger)Secretogranin_V (PF05281)   
Domain families : Pfam (NCBI)pfam05281   
Conserved Domain (NCBI)SCG5
DMDM Disease mutations6447
Blocks (Seattle)SCG5
SuperfamilyP05408
Human Protein AtlasENSG00000166922
Peptide AtlasP05408
HPRD01410
IPIIPI00008944   IPI00470716   IPI01009468   IPI00790525   IPI00945122   
Protein Interaction databases
DIP (DOE-UCLA)P05408
IntAct (EBI)P05408
FunCoupENSG00000166922
BioGRIDSCG5
STRING (EMBL)SCG5
ZODIACSCG5
Ontologies - Pathways
QuickGOP05408
Ontology : AmiGOenzyme inhibitor activity  protein binding  GTP binding  extracellular region  intracellular protein transport  neuropeptide signaling pathway  peptide hormone processing  secretory granule  negative regulation of catalytic activity  regulation of hormone secretion  unfolded protein binding  
Ontology : EGO-EBIenzyme inhibitor activity  protein binding  GTP binding  extracellular region  intracellular protein transport  neuropeptide signaling pathway  peptide hormone processing  secretory granule  negative regulation of catalytic activity  regulation of hormone secretion  unfolded protein binding  
NDEx NetworkSCG5
Atlas of Cancer Signalling NetworkSCG5
Wikipedia pathwaysSCG5
Orthology - Evolution
OrthoDB6447
GeneTree (enSembl)ENSG00000166922
Phylogenetic Trees/Animal Genes : TreeFamSCG5
HOVERGENP05408
HOGENOMP05408
Homologs : HomoloGeneSCG5
Homology/Alignments : Family Browser (UCSC)SCG5
Gene fusions - Rearrangements
Fusion : MitelmanSNX1/SCG5 [15q22.31/15q13.3]  [t(15;15)(q13;q22)]  
Fusion : MitelmanZNF385B/SCG5 [2q31.2/15q13.3]  [t(2;15)(q31;q13)]  
Fusion: TCGASNX1 15q22.31 SCG5 15q13.3 SKCM
Fusion: TCGAZNF385B 2q31.2 SCG5 15q13.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSCG5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SCG5
dbVarSCG5
ClinVarSCG5
1000_GenomesSCG5 
Exome Variant ServerSCG5
ExAC (Exome Aggregation Consortium)SCG5 (select the gene name)
Genetic variants : HAPMAP6447
Genomic Variants (DGV)SCG5 [DGVbeta]
DECIPHERSCG5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSCG5 
Mutations
ICGC Data PortalSCG5 
TCGA Data PortalSCG5 
Broad Tumor PortalSCG5
OASIS PortalSCG5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSCG5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSCG5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SCG5
DgiDB (Drug Gene Interaction Database)SCG5
DoCM (Curated mutations)SCG5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SCG5 (select a term)
intoGenSCG5
Cancer3DSCG5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM173120   
Orphanet
MedgenSCG5
Genetic Testing Registry SCG5
NextProtP05408 [Medical]
TSGene6447
GENETestsSCG5
Target ValidationSCG5
Huge Navigator SCG5 [HugePedia]
snp3D : Map Gene to Disease6447
BioCentury BCIQSCG5
ClinGenSCG5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6447
Chemical/Pharm GKB GenePA35724
Clinical trialSCG5
Miscellaneous
canSAR (ICR)SCG5 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSCG5
EVEXSCG5
GoPubMedSCG5
iHOPSCG5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:13:48 CEST 2017

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