Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC46A1 (solute carrier family 46 (folate transporter), member 1)

Identity

Other namesG21
HCP1
PCFT
HGNC (Hugo) SLC46A1
LocusID (NCBI) 113235
Location 17q11.2
Location_base_pair Starts at 26721661 and ends at 26733230 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SLC46A1   30521
Cards
Entrez_Gene (NCBI)SLC46A1  113235  solute carrier family 46 (folate transporter), member 1
GeneCards (Weizmann)SLC46A1
Ensembl (Hinxton)ENSG00000076351 [Gene_View]  chr17:26721661-26733230 [Contig_View]  SLC46A1 [Vega]
ICGC DataPortalENSG00000076351
cBioPortalSLC46A1
AceView (NCBI)SLC46A1
Genatlas (Paris)SLC46A1
WikiGenes113235
SOURCE (Princeton)NM_001242366 NM_080669
Genomic and cartography
GoldenPath (UCSC)SLC46A1  -  17q11.2   chr17:26721661-26733230 -  17q11.2   [Description]    (hg19-Feb_2009)
EnsemblSLC46A1 - 17q11.2 [CytoView]
Mapping of homologs : NCBISLC46A1 [Mapview]
OMIM229050   611672   
Gene and transcription
Genbank (Entrez)AK054669 AK074161 AK097194 AK295883 AL832613
RefSeq transcript (Entrez)NM_001242366 NM_080669
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NG_013306 NT_010783 NW_001838430 NW_004929407
Consensus coding sequences : CCDS (NCBI)SLC46A1
Cluster EST : UnigeneHs.446689 [ NCBI ]
CGAP (NCI)Hs.446689
Alternative Splicing : Fast-db (Paris)GSHG0013212
Alternative Splicing GalleryENSG00000076351
Gene ExpressionSLC46A1 [ NCBI-GEO ]     SLC46A1 [ SEEK ]   SLC46A1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96NT5 (Uniprot)
NextProtQ96NT5  [Medical]
With graphics : InterProQ96NT5
Splice isoforms : SwissVarQ96NT5 (Swissvar)
Domaine pattern : Prosite (Expaxy)MFS (PS50850)   
Domains : Interpro (EBI)MFS [organisation]   MFS_dom [organisation]   MFS_dom_general_subst_transpt [organisation]   Sugar_transporter_CS [organisation]  
Related proteins : CluSTrQ96NT5
Domain families : Pfam (Sanger)MFS_1 (PF07690)   
Domain families : Pfam (NCBI)pfam07690   
DMDM Disease mutations113235
Blocks (Seattle)Q96NT5
Human Protein AtlasENSG00000076351 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ96NT5
HPRD14715
IPIIPI00043883   IPI00550230   IPI01018362   
Protein Interaction databases
DIP (DOE-UCLA)Q96NT5
IntAct (EBI)Q96NT5
FunCoupENSG00000076351
BioGRIDSLC46A1
InParanoidQ96NT5
Interologous Interaction database Q96NT5
IntegromeDBSLC46A1
STRING (EMBL)SLC46A1
Ontologies - Pathways
Ontology : AmiGOfolic acid binding  cytoplasm  plasma membrane  vitamin metabolic process  water-soluble vitamin metabolic process  cellular iron ion homeostasis  folic acid transporter activity  heme transporter activity  methotrexate transporter activity  folic acid transport  heme transport  integral component of membrane  apical plasma membrane  brush border membrane  small molecule metabolic process  folic acid metabolic process  methotrexate transport  transmembrane transport  
Ontology : EGO-EBIfolic acid binding  cytoplasm  plasma membrane  vitamin metabolic process  water-soluble vitamin metabolic process  cellular iron ion homeostasis  folic acid transporter activity  heme transporter activity  methotrexate transporter activity  folic acid transport  heme transport  integral component of membrane  apical plasma membrane  brush border membrane  small molecule metabolic process  folic acid metabolic process  methotrexate transport  transmembrane transport  
Pathways : KEGGVitamin digestion and absorption    Mineral absorption   
Protein Interaction DatabaseSLC46A1
Wikipedia pathwaysSLC46A1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SLC46A1
snp3D : Map Gene to Disease113235
SNP (GeneSNP Utah)SLC46A1
SNP : HGBaseSLC46A1
Genetic variants : HAPMAPSLC46A1
Exome VariantSLC46A1
1000_GenomesSLC46A1 
ICGC programENSG00000076351 
Somatic Mutations in Cancer : COSMICSLC46A1 
CONAN: Copy Number AnalysisSLC46A1 
Mutations and Diseases : HGMDSLC46A1
Mutations and Diseases : intOGenSLC46A1
Genomic VariantsSLC46A1  SLC46A1 [DGVbeta]
dbVarSLC46A1
ClinVarSLC46A1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM229050    611672   
MedgenSLC46A1
GENETestsSLC46A1
Disease Genetic AssociationSLC46A1
Huge Navigator SLC46A1 [HugePedia]  SLC46A1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneSLC46A1
Homology/Alignments : Family Browser (UCSC)SLC46A1
Phylogenetic Trees/Animal Genes : TreeFamSLC46A1
Chemical/Protein Interactions : CTD113235
Chemical/Pharm GKB GenePA162403775
Clinical trialSLC46A1
Cancer Resource (Charite)ENSG00000076351
Other databases
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
CoreMineSLC46A1
iHOPSLC46A1
OncoSearchSLC46A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 19:18:53 CEST 2014

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