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SPON2 (spondin 2)

Identity

Alias_namesspondin 2
Alias_symbol (synonym)DIL1
Other aliasDIL-1
M-SPONDIN
MINDIN
HGNC (Hugo) SPON2
LocusID (NCBI) 10417
Atlas_Id 42378
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 1166933 and ends at 1173211 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPON2   11253
Cards
Entrez_Gene (NCBI)SPON2  10417  spondin 2
AliasesDIL-1; DIL1; M-SPONDIN; MINDIN
GeneCards (Weizmann)SPON2
Ensembl hg19 (Hinxton)ENSG00000159674 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159674 [Gene_View]  chr4:1166933-1173211 [Contig_View]  SPON2 [Vega]
ICGC DataPortalENSG00000159674
TCGA cBioPortalSPON2
AceView (NCBI)SPON2
Genatlas (Paris)SPON2
WikiGenes10417
SOURCE (Princeton)SPON2
Genetics Home Reference (NIH)SPON2
Genomic and cartography
GoldenPath hg38 (UCSC)SPON2  -     chr4:1166933-1173211 -  4p16.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPON2  -     4p16.3   [Description]    (hg19-Feb_2009)
EnsemblSPON2 - 4p16.3 [CytoView hg19]  SPON2 - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBISPON2 [Mapview hg19]  SPON2 [Mapview hg38]
OMIM605918   
Gene and transcription
Genbank (Entrez)AA864573 AB027466 AK024499 AK026054 AK074618
RefSeq transcript (Entrez)NM_001128325 NM_001199021 NM_012445
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SPON2
Cluster EST : UnigeneHs.736956 [ NCBI ]
CGAP (NCI)Hs.736956
Alternative Splicing GalleryENSG00000159674
Gene ExpressionSPON2 [ NCBI-GEO ]   SPON2 [ EBI - ARRAY_EXPRESS ]   SPON2 [ SEEK ]   SPON2 [ MEM ]
Gene Expression Viewer (FireBrowse)SPON2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10417
GTEX Portal (Tissue expression)SPON2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BUD6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BUD6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BUD6
Splice isoforms : SwissVarQ9BUD6
PhosPhoSitePlusQ9BUD6
Domaine pattern : Prosite (Expaxy)SPONDIN (PS51020)    TSP1 (PS50092)   
Domains : Interpro (EBI)Spondin_N    TSP1_rpt   
Domain families : Pfam (Sanger)Spond_N (PF06468)    TSP_1 (PF00090)   
Domain families : Pfam (NCBI)pfam06468    pfam00090   
Domain families : Smart (EMBL)TSP1 (SM00209)  
Conserved Domain (NCBI)SPON2
DMDM Disease mutations10417
Blocks (Seattle)SPON2
PDB (SRS)3D34   
PDB (PDBSum)3D34   
PDB (IMB)3D34   
PDB (RSDB)3D34   
Structural Biology KnowledgeBase3D34   
SCOP (Structural Classification of Proteins)3D34   
CATH (Classification of proteins structures)3D34   
SuperfamilyQ9BUD6
Human Protein AtlasENSG00000159674
Peptide AtlasQ9BUD6
HPRD16174
IPIIPI00305975   IPI00386302   IPI00964513   IPI00965689   IPI00964820   IPI00965987   IPI00964209   IPI00963903   IPI00967524   
Protein Interaction databases
DIP (DOE-UCLA)Q9BUD6
IntAct (EBI)Q9BUD6
FunCoupENSG00000159674
BioGRIDSPON2
STRING (EMBL)SPON2
ZODIACSPON2
Ontologies - Pathways
QuickGOQ9BUD6
Ontology : AmiGOlipopolysaccharide binding  mast cell mediated immunity  antigen binding  protein binding  proteinaceous extracellular matrix  extracellular space  cell adhesion  axon guidance  opsonization  positive regulation of interleukin-6 production  positive regulation of tumor necrosis factor production  induction of bacterial agglutination  innate immune response  metal ion binding  defense response to fungus  defense response to virus  positive regulation of macrophage cytokine production  extracellular exosome  cellular response to lipopolysaccharide  
Ontology : EGO-EBIlipopolysaccharide binding  mast cell mediated immunity  antigen binding  protein binding  proteinaceous extracellular matrix  extracellular space  cell adhesion  axon guidance  opsonization  positive regulation of interleukin-6 production  positive regulation of tumor necrosis factor production  induction of bacterial agglutination  innate immune response  metal ion binding  defense response to fungus  defense response to virus  positive regulation of macrophage cytokine production  extracellular exosome  cellular response to lipopolysaccharide  
NDEx NetworkSPON2
Atlas of Cancer Signalling NetworkSPON2
Wikipedia pathwaysSPON2
Orthology - Evolution
OrthoDB10417
GeneTree (enSembl)ENSG00000159674
Phylogenetic Trees/Animal Genes : TreeFamSPON2
HOVERGENQ9BUD6
HOGENOMQ9BUD6
Homologs : HomoloGeneSPON2
Homology/Alignments : Family Browser (UCSC)SPON2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPON2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPON2
dbVarSPON2
ClinVarSPON2
1000_GenomesSPON2 
Exome Variant ServerSPON2
ExAC (Exome Aggregation Consortium)SPON2 (select the gene name)
Genetic variants : HAPMAP10417
Genomic Variants (DGV)SPON2 [DGVbeta]
DECIPHERSPON2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPON2 
Mutations
ICGC Data PortalSPON2 
TCGA Data PortalSPON2 
Broad Tumor PortalSPON2
OASIS PortalSPON2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPON2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPON2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPON2
DgiDB (Drug Gene Interaction Database)SPON2
DoCM (Curated mutations)SPON2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPON2 (select a term)
intoGenSPON2
Cancer3DSPON2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605918   
Orphanet
MedgenSPON2
Genetic Testing Registry SPON2
NextProtQ9BUD6 [Medical]
TSGene10417
GENETestsSPON2
Target ValidationSPON2
Huge Navigator SPON2 [HugePedia]
snp3D : Map Gene to Disease10417
BioCentury BCIQSPON2
ClinGenSPON2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10417
Chemical/Pharm GKB GenePA36083
Clinical trialSPON2
Miscellaneous
canSAR (ICR)SPON2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPON2
EVEXSPON2
GoPubMedSPON2
iHOPSPON2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:08:22 CEST 2017

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