Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SPSB2 (splA/ryanodine receptor domain and SOCS box containing 2)

Identity

Alias_symbol (synonym)GRCC9
SSB-2
Other aliasSSB2
HGNC (Hugo) SPSB2
LocusID (NCBI) 84727
Atlas_Id 51160
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 6980100 and ends at 6982449 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPSB2   29522
Cards
Entrez_Gene (NCBI)SPSB2  84727  splA/ryanodine receptor domain and SOCS box containing 2
AliasesGRCC9; SSB2
GeneCards (Weizmann)SPSB2
Ensembl hg19 (Hinxton)ENSG00000111671 [Gene_View]  chr12:6980100-6982449 [Contig_View]  SPSB2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000111671 [Gene_View]  chr12:6980100-6982449 [Contig_View]  SPSB2 [Vega]
ICGC DataPortalENSG00000111671
TCGA cBioPortalSPSB2
AceView (NCBI)SPSB2
Genatlas (Paris)SPSB2
WikiGenes84727
SOURCE (Princeton)SPSB2
Genetics Home Reference (NIH)SPSB2
Genomic and cartography
GoldenPath hg19 (UCSC)SPSB2  -     chr12:6980100-6982449 -  12p13.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SPSB2  -     12p13.31   [Description]    (hg38-Dec_2013)
EnsemblSPSB2 - 12p13.31 [CytoView hg19]  SPSB2 - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBISPSB2 [Mapview hg19]  SPSB2 [Mapview hg38]
OMIM611658   
Gene and transcription
Genbank (Entrez)AF403027 AK297963 AK310353 BC002983 BC071933
RefSeq transcript (Entrez)NM_001146316 NM_001146317 NM_001319670 NM_032641
RefSeq genomic (Entrez)NC_000012 NC_018923 NG_013308 NT_009759 NW_004929382
Consensus coding sequences : CCDS (NCBI)SPSB2
Cluster EST : UnigeneHs.479856 [ NCBI ]
CGAP (NCI)Hs.479856
Alternative Splicing GalleryENSG00000111671
Gene ExpressionSPSB2 [ NCBI-GEO ]   SPSB2 [ EBI - ARRAY_EXPRESS ]   SPSB2 [ SEEK ]   SPSB2 [ MEM ]
Gene Expression Viewer (FireBrowse)SPSB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84727
GTEX Portal (Tissue expression)SPSB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99619   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99619  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99619
Splice isoforms : SwissVarQ99619
PhosPhoSitePlusQ99619
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    SOCS (PS50225)   
Domains : Interpro (EBI)B30.2/SPRY    ConA-like_dom    SOCS_box    SPRY_dom   
Domain families : Pfam (Sanger)SOCS_box (PF07525)    SPRY (PF00622)   
Domain families : Pfam (NCBI)pfam07525    pfam00622   
Domain families : Smart (EMBL)SOCS_box (SM00969)  SPRY (SM00449)  
Conserved Domain (NCBI)SPSB2
DMDM Disease mutations84727
Blocks (Seattle)SPSB2
PDB (SRS)3EMW   
PDB (PDBSum)3EMW   
PDB (IMB)3EMW   
PDB (RSDB)3EMW   
Structural Biology KnowledgeBase3EMW   
SCOP (Structural Classification of Proteins)3EMW   
CATH (Classification of proteins structures)3EMW   
SuperfamilyQ99619
Human Protein AtlasENSG00000111671
Peptide AtlasQ99619
HPRD13610
IPIIPI00013315   IPI01009447   IPI00979897   
Protein Interaction databases
DIP (DOE-UCLA)Q99619
IntAct (EBI)Q99619
FunCoupENSG00000111671
BioGRIDSPSB2
STRING (EMBL)SPSB2
ZODIACSPSB2
Ontologies - Pathways
QuickGOQ99619
Ontology : AmiGOmolecular_function  protein binding  cellular_component  cytoplasm  biological_process  protein ubiquitination  intracellular signal transduction  
Ontology : EGO-EBImolecular_function  protein binding  cellular_component  cytoplasm  biological_process  protein ubiquitination  intracellular signal transduction  
NDEx NetworkSPSB2
Atlas of Cancer Signalling NetworkSPSB2
Wikipedia pathwaysSPSB2
Orthology - Evolution
OrthoDB84727
GeneTree (enSembl)ENSG00000111671
Phylogenetic Trees/Animal Genes : TreeFamSPSB2
HOVERGENQ99619
HOGENOMQ99619
Homologs : HomoloGeneSPSB2
Homology/Alignments : Family Browser (UCSC)SPSB2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPSB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPSB2
dbVarSPSB2
ClinVarSPSB2
1000_GenomesSPSB2 
Exome Variant ServerSPSB2
ExAC (Exome Aggregation Consortium)SPSB2 (select the gene name)
Genetic variants : HAPMAP84727
Genomic Variants (DGV)SPSB2 [DGVbeta]
DECIPHER (Syndromes)12:6980100-6982449  ENSG00000111671
CONAN: Copy Number AnalysisSPSB2 
Mutations
ICGC Data PortalSPSB2 
TCGA Data PortalSPSB2 
Broad Tumor PortalSPSB2
OASIS PortalSPSB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPSB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPSB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPSB2
DgiDB (Drug Gene Interaction Database)SPSB2
DoCM (Curated mutations)SPSB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPSB2 (select a term)
intoGenSPSB2
Cancer3DSPSB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611658   
Orphanet
MedgenSPSB2
Genetic Testing Registry SPSB2
NextProtQ99619 [Medical]
TSGene84727
GENETestsSPSB2
Huge Navigator SPSB2 [HugePedia]
snp3D : Map Gene to Disease84727
BioCentury BCIQSPSB2
ClinGenSPSB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84727
Chemical/Pharm GKB GenePA142670872
Clinical trialSPSB2
Miscellaneous
canSAR (ICR)SPSB2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPSB2
EVEXSPSB2
GoPubMedSPSB2
iHOPSPSB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:29:02 CET 2017

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