Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SRSF7 (serine and arginine rich splicing factor 7)

Identity

Alias_namesSFRS7
splicing factor, arginine/serine-rich 7 (35kD)
splicing factor, arginine/serine-rich 7, 35kDa
serine/arginine-rich splicing factor 7
Alias_symbol (synonym)9G8
ZCRB2
HSSG1
AAG3
RBM37
ZCCHC20
Other alias
HGNC (Hugo) SRSF7
LocusID (NCBI) 6432
Atlas_Id 53403
Location 2p22.1  [Link to chromosome band 2p22]
Location_base_pair Starts at 38743599 and ends at 38751494 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AP1AR (4q25) / SRSF7 (2p22.1)SRSF7 (2p22.1) / PECAM1 (17q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SRSF7   10789
Cards
Entrez_Gene (NCBI)SRSF7  6432  serine and arginine rich splicing factor 7
Aliases9G8; AAG3; SFRS7
GeneCards (Weizmann)SRSF7
Ensembl hg19 (Hinxton)ENSG00000115875 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115875 [Gene_View]  chr2:38743599-38751494 [Contig_View]  SRSF7 [Vega]
ICGC DataPortalENSG00000115875
TCGA cBioPortalSRSF7
AceView (NCBI)SRSF7
Genatlas (Paris)SRSF7
WikiGenes6432
SOURCE (Princeton)SRSF7
Genetics Home Reference (NIH)SRSF7
Genomic and cartography
GoldenPath hg38 (UCSC)SRSF7  -     chr2:38743599-38751494 -  2p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SRSF7  -     2p22.1   [Description]    (hg19-Feb_2009)
EnsemblSRSF7 - 2p22.1 [CytoView hg19]  SRSF7 - 2p22.1 [CytoView hg38]
Mapping of homologs : NCBISRSF7 [Mapview hg19]  SRSF7 [Mapview hg38]
OMIM600572   
Gene and transcription
Genbank (Entrez)AB445102 AF055270 AK091425 AK225141 AK293667
RefSeq transcript (Entrez)NM_001031684 NM_001195446 NM_006276
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SRSF7
Cluster EST : UnigeneHs.309090 [ NCBI ]
CGAP (NCI)Hs.309090
Alternative Splicing GalleryENSG00000115875
Gene ExpressionSRSF7 [ NCBI-GEO ]   SRSF7 [ EBI - ARRAY_EXPRESS ]   SRSF7 [ SEEK ]   SRSF7 [ MEM ]
Gene Expression Viewer (FireBrowse)SRSF7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6432
GTEX Portal (Tissue expression)SRSF7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16629   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16629  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16629
Splice isoforms : SwissVarQ16629
PhosPhoSitePlusQ16629
Domaine pattern : Prosite (Expaxy)RRM (PS50102)    ZF_CCHC (PS50158)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    RRM_dom    Znf_CCHC   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)SRSF7
DMDM Disease mutations6432
Blocks (Seattle)SRSF7
PDB (SRS)2HVZ   
PDB (PDBSum)2HVZ   
PDB (IMB)2HVZ   
PDB (RSDB)2HVZ   
Structural Biology KnowledgeBase2HVZ   
SCOP (Structural Classification of Proteins)2HVZ   
CATH (Classification of proteins structures)2HVZ   
SuperfamilyQ16629
Human Protein AtlasENSG00000115875
Peptide AtlasQ16629
HPRD08991
IPIIPI00003377   IPI00744364   IPI00384387   IPI00917346   IPI00215907   IPI01011358   IPI00917135   IPI00916448   
Protein Interaction databases
DIP (DOE-UCLA)Q16629
IntAct (EBI)Q16629
FunCoupENSG00000115875
BioGRIDSRSF7
STRING (EMBL)SRSF7
ZODIACSRSF7
Ontologies - Pathways
QuickGOQ16629
Ontology : AmiGOmRNA splicing, via spliceosome  RNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  termination of RNA polymerase II transcription  mRNA processing  RNA export from nucleus  mRNA export from nucleus  zinc ion binding  RNA splicing  mRNA 3'-end processing  negative regulation of mRNA splicing, via spliceosome  extracellular exosome  
Ontology : EGO-EBImRNA splicing, via spliceosome  RNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  termination of RNA polymerase II transcription  mRNA processing  RNA export from nucleus  mRNA export from nucleus  zinc ion binding  RNA splicing  mRNA 3'-end processing  negative regulation of mRNA splicing, via spliceosome  extracellular exosome  
Pathways : KEGGSpliceosome    Herpes simplex infection   
NDEx NetworkSRSF7
Atlas of Cancer Signalling NetworkSRSF7
Wikipedia pathwaysSRSF7
Orthology - Evolution
OrthoDB6432
GeneTree (enSembl)ENSG00000115875
Phylogenetic Trees/Animal Genes : TreeFamSRSF7
HOVERGENQ16629
HOGENOMQ16629
Homologs : HomoloGeneSRSF7
Homology/Alignments : Family Browser (UCSC)SRSF7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSRSF7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRSF7
dbVarSRSF7
ClinVarSRSF7
1000_GenomesSRSF7 
Exome Variant ServerSRSF7
ExAC (Exome Aggregation Consortium)SRSF7 (select the gene name)
Genetic variants : HAPMAP6432
Genomic Variants (DGV)SRSF7 [DGVbeta]
DECIPHERSRSF7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSRSF7 
Mutations
ICGC Data PortalSRSF7 
TCGA Data PortalSRSF7 
Broad Tumor PortalSRSF7
OASIS PortalSRSF7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSRSF7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSRSF7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SRSF7
DgiDB (Drug Gene Interaction Database)SRSF7
DoCM (Curated mutations)SRSF7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SRSF7 (select a term)
intoGenSRSF7
Cancer3DSRSF7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600572   
Orphanet
MedgenSRSF7
Genetic Testing Registry SRSF7
NextProtQ16629 [Medical]
TSGene6432
GENETestsSRSF7
Target ValidationSRSF7
Huge Navigator SRSF7 [HugePedia]
snp3D : Map Gene to Disease6432
BioCentury BCIQSRSF7
ClinGenSRSF7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6432
Chemical/Pharm GKB GenePA35705
Clinical trialSRSF7
Miscellaneous
canSAR (ICR)SRSF7 (select the gene name)
Probes
Litterature
PubMed84 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSRSF7
EVEXSRSF7
GoPubMedSRSF7
iHOPSRSF7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:57:28 CEST 2017

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