SRSF7 (serine and arginine rich splicing factor 7)

2013-06-01  

Identity

HGNC
LOCATION
2p22.1
LOCUSID
ALIAS
9G8,AAG3,SFRS7
FUSION GENES

Other Information

Locus ID:

NCBI: 6432
MIM: 600572
HGNC: 10789
Ensembl: ENSG00000115875

Variants:

dbSNP: 6432
ClinVar: 6432
TCGA: ENSG00000115875
COSMIC: SRSF7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115875ENST00000313117Q16629
ENSG00000115875ENST00000409276C9JAB2
ENSG00000115875ENST00000415527F8WEA1
ENSG00000115875ENST00000425778A0A0B4J1Z1
ENSG00000115875ENST00000425941A0A0B4J1Z1
ENSG00000115875ENST00000431066Q16629
ENSG00000115875ENST00000432873H7C1N1
ENSG00000115875ENST00000443213Q16629
ENSG00000115875ENST00000446327Q16629
ENSG00000115875ENST00000452806H7BZZ6

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Herpes simplex infectionKEGGko05168
Herpes simplex infectionKEGGhsa05168
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Transcription TerminationREACTOMER-HSA-73856
Cleavage of Growing Transcript in the Termination RegionREACTOMER-HSA-109688
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163
mRNA Splicing - Minor PathwayREACTOMER-HSA-72165
mRNA 3'-end processingREACTOMER-HSA-72187
Transport of Mature Transcript to CytoplasmREACTOMER-HSA-72202
Transport of Mature mRNA derived from an Intron-Containing TranscriptREACTOMER-HSA-159236

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
349541292023Specific Regulation of m(6)A by SRSF7 Promotes the Progression of Glioblastoma.15
381592472023SRSF7 downregulation induces cellular senescence through generation of MDM2 variants.1
349541292023Specific Regulation of m(6)A by SRSF7 Promotes the Progression of Glioblastoma.15
381592472023SRSF7 downregulation induces cellular senescence through generation of MDM2 variants.1
357805862022The splicing factor 9G8 regulates the expression of NADPH-producing enzyme genes in Drosophila.1
357805862022The splicing factor 9G8 regulates the expression of NADPH-producing enzyme genes in Drosophila.1
340966022021Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway.11
340966022021Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway.11
321415542020Long non-coding RNA MALAT1 regulates proliferation, apoptosis, migration and invasion via miR-374b-5p/SRSF7 axis in non-small cell lung cancer.25
321415542020Long non-coding RNA MALAT1 regulates proliferation, apoptosis, migration and invasion via miR-374b-5p/SRSF7 axis in non-small cell lung cancer.25
276445622016Serine/arginine-rich splicing factor 7 regulates p21-dependent growth arrest in colon cancer cells.19
276645842016microRNAs target SRSF7 splicing factor to modulate the expression of osteopontin splice variants in renal cancer cells.22
276445622016Serine/arginine-rich splicing factor 7 regulates p21-dependent growth arrest in colon cancer cells.19
276645842016microRNAs target SRSF7 splicing factor to modulate the expression of osteopontin splice variants in renal cancer cells.22
254825082015Genome-wide identification of Fas/CD95 alternative splicing regulators reveals links with iron homeostasis.47

Citation

Dessen P

SRSF7 (serine and arginine rich splicing factor 7)

Atlas Genet Cytogenet Oncol Haematol. 2013-06-01

Online version: http://atlasgeneticsoncology.org/gene/53403/srsf7