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STS (steroid sulfatase (microsomal), isozyme S)

Identity

Alias_namesARSC1
steroid sulfatase (microsomal)
Alias_symbol (synonym)ARSC
Other aliasASC
ES
SSDD
XLI
HGNC (Hugo) STS
LocusID (NCBI) 412
Atlas_Id 43814
Location Xp22.31  [Link to chromosome band Xp22]
Location_base_pair Starts at 7137472 and ends at 7272682 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
STS (Xp22.31) / SEPW1 (19q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STS   11425
Cards
Entrez_Gene (NCBI)STS  412  steroid sulfatase (microsomal), isozyme S
AliasesARSC; ARSC1; ASC; ES; 
SSDD; XLI
GeneCards (Weizmann)STS
Ensembl hg19 (Hinxton)ENSG00000101846 [Gene_View]  chrX:7137472-7272682 [Contig_View]  STS [Vega]
Ensembl hg38 (Hinxton)ENSG00000101846 [Gene_View]  chrX:7137472-7272682 [Contig_View]  STS [Vega]
ICGC DataPortalENSG00000101846
TCGA cBioPortalSTS
AceView (NCBI)STS
Genatlas (Paris)STS
WikiGenes412
SOURCE (Princeton)STS
Genetics Home Reference (NIH)STS
Genomic and cartography
GoldenPath hg19 (UCSC)STS  -     chrX:7137472-7272682 +  Xp22.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)STS  -     Xp22.31   [Description]    (hg38-Dec_2013)
EnsemblSTS - Xp22.31 [CytoView hg19]  STS - Xp22.31 [CytoView hg38]
Mapping of homologs : NCBISTS [Mapview hg19]  STS [Mapview hg38]
OMIM300747   308100   
Gene and transcription
Genbank (Entrez)AK314034 AL133910 AL549736 AM072428 AM072429
RefSeq transcript (Entrez)NM_000351 NM_001320750 NM_001320751 NM_001320752 NM_001320753 NM_001320754
RefSeq genomic (Entrez)NC_000023 NC_018934 NG_021472 NT_167197 NW_004929438
Consensus coding sequences : CCDS (NCBI)STS
Cluster EST : UnigeneHs.740067 [ NCBI ]
CGAP (NCI)Hs.740067
Alternative Splicing GalleryENSG00000101846
Gene ExpressionSTS [ NCBI-GEO ]   STS [ EBI - ARRAY_EXPRESS ]   STS [ SEEK ]   STS [ MEM ]
Gene Expression Viewer (FireBrowse)STS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)412
GTEX Portal (Tissue expression)STS
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08842   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08842  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08842
Splice isoforms : SwissVarP08842
Catalytic activity : Enzyme3.1.6.2 [ Enzyme-Expasy ]   3.1.6.23.1.6.2 [ IntEnz-EBI ]   3.1.6.2 [ BRENDA ]   3.1.6.2 [ KEGG ]   
PhosPhoSitePlusP08842
Domaine pattern : Prosite (Expaxy)SULFATASE_1 (PS00523)    SULFATASE_2 (PS00149)   
Domains : Interpro (EBI)Alkaline_Pase-like_a/b/a    Alkaline_phosphatase_core    Sulfatase_CS    Sulfatase_N   
Domain families : Pfam (Sanger)Sulfatase (PF00884)   
Domain families : Pfam (NCBI)pfam00884   
Conserved Domain (NCBI)STS
DMDM Disease mutations412
Blocks (Seattle)STS
PDB (SRS)1P49   
PDB (PDBSum)1P49   
PDB (IMB)1P49   
PDB (RSDB)1P49   
Structural Biology KnowledgeBase1P49   
SCOP (Structural Classification of Proteins)1P49   
CATH (Classification of proteins structures)1P49   
SuperfamilyP08842
Human Protein AtlasENSG00000101846
Peptide AtlasP08842
HPRD02389
IPIIPI00307433   IPI00816525   
Protein Interaction databases
DIP (DOE-UCLA)P08842
IntAct (EBI)P08842
FunCoupENSG00000101846
BioGRIDSTS
STRING (EMBL)STS
ZODIACSTS
Ontologies - Pathways
QuickGOP08842
Ontology : AmiGOsteryl-sulfatase activity  nuclear envelope  lysosome  endosome  endoplasmic reticulum  endoplasmic reticulum lumen  endoplasmic reticulum membrane  Golgi apparatus  plasma membrane  glycosphingolipid metabolic process  steroid catabolic process  female pregnancy  learning or memory  positive regulation of cell proliferation  sulfuric ester hydrolase activity  epidermis development  response to pH  membrane  integral component of membrane  intracellular membrane-bounded organelle  response to peptide hormone  skin development  response to estrogen  post-translational protein modification  metal ion binding  
Ontology : EGO-EBIsteryl-sulfatase activity  nuclear envelope  lysosome  endosome  endoplasmic reticulum  endoplasmic reticulum lumen  endoplasmic reticulum membrane  Golgi apparatus  plasma membrane  glycosphingolipid metabolic process  steroid catabolic process  female pregnancy  learning or memory  positive regulation of cell proliferation  sulfuric ester hydrolase activity  epidermis development  response to pH  membrane  integral component of membrane  intracellular membrane-bounded organelle  response to peptide hormone  skin development  response to estrogen  post-translational protein modification  metal ion binding  
Pathways : KEGGSteroid hormone biosynthesis   
NDEx NetworkSTS
Atlas of Cancer Signalling NetworkSTS
Wikipedia pathwaysSTS
Orthology - Evolution
OrthoDB412
GeneTree (enSembl)ENSG00000101846
Phylogenetic Trees/Animal Genes : TreeFamSTS
HOVERGENP08842
HOGENOMP08842
Homologs : HomoloGeneSTS
Homology/Alignments : Family Browser (UCSC)STS
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STS
dbVarSTS
ClinVarSTS
1000_GenomesSTS 
Exome Variant ServerSTS
ExAC (Exome Aggregation Consortium)STS (select the gene name)
Genetic variants : HAPMAP412
Genomic Variants (DGV)STS [DGVbeta]
DECIPHER (Syndromes)X:7137472-7272682  ENSG00000101846
CONAN: Copy Number AnalysisSTS 
Mutations
ICGC Data PortalSTS 
TCGA Data PortalSTS 
Broad Tumor PortalSTS
OASIS PortalSTS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STS
DgiDB (Drug Gene Interaction Database)STS
DoCM (Curated mutations)STS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STS (select a term)
intoGenSTS
Cancer3DSTS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300747    308100   
Orphanet42    20525   
MedgenSTS
Genetic Testing Registry STS
NextProtP08842 [Medical]
TSGene412
GENETestsSTS
Huge Navigator STS [HugePedia]
snp3D : Map Gene to Disease412
BioCentury BCIQSTS
ClinGenSTS (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD412
Chemical/Pharm GKB GenePA36225
Clinical trialSTS
Miscellaneous
canSAR (ICR)STS (select the gene name)
Probes
Litterature
PubMed83 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTS
EVEXSTS
GoPubMedSTS
iHOPSTS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:29:45 CET 2017

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