Identity
HGNC
LOCATION
Xp22.31
LOCUSID
ALIAS
ARSC,ARSC1,ASC,ES,SSDD,XLI
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 412
MIM: 300747
HGNC: 11425
Ensembl: ENSG00000101846
Variants:
dbSNP: 412
ClinVar: 412
TCGA: ENSG00000101846
COSMIC: STS
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101846 | ENST00000217961 | P08842 |
| ENSG00000101846 | ENST00000660000 | A0A590UJY9 |
| ENSG00000101846 | ENST00000664306 | A0A590UJT4 |
| ENSG00000101846 | ENST00000666110 | A0A590UJL0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36427797 | 2023 | Structure of human placental steroid sulfatase at 2.0 angstrom resolution: Catalysis, quaternary association, and a secondary ligand site. | 1 |
| 36789964 | 2023 | Biallelic mutations in FLG, TGM1, and STS genes segregated with different types of ichthyoses in eight families of Pakistani origin. | 0 |
| 37895274 | 2023 | STS and PUDP Deletion Identified by Targeted Panel Sequencing with CNV Analysis in X-Linked Ichthyosis: A Case Report and Literature Review. | 1 |
| 36427797 | 2023 | Structure of human placental steroid sulfatase at 2.0 angstrom resolution: Catalysis, quaternary association, and a secondary ligand site. | 1 |
| 36789964 | 2023 | Biallelic mutations in FLG, TGM1, and STS genes segregated with different types of ichthyoses in eight families of Pakistani origin. | 0 |
| 37895274 | 2023 | STS and PUDP Deletion Identified by Targeted Panel Sequencing with CNV Analysis in X-Linked Ichthyosis: A Case Report and Literature Review. | 1 |
| 32705921 | 2021 | Lead optimization of 4-(thio)-chromenone 6-O-sulfamate analogs using QSAR, molecular docking and DFT - a combined approach as steroidal sulfatase inhibitors. | 0 |
| 33290605 | 2021 | Testicular steroid sulfatase overexpression is associated with Leydig cell dysfunction in primary spermatogenic failure. | 1 |
| 33336383 | 2021 | A novel STS mutation and an Xp22.31 microdeletion in a Chinese family with X-linked ichthyosis. | 0 |
| 34675221 | 2021 | Steroid sulfatase deficiency causes cellular senescence and abnormal differentiation by inducing Yippee-like 3 expression in human keratinocytes. | 0 |
| 32705921 | 2021 | Lead optimization of 4-(thio)-chromenone 6-O-sulfamate analogs using QSAR, molecular docking and DFT - a combined approach as steroidal sulfatase inhibitors. | 0 |
| 33290605 | 2021 | Testicular steroid sulfatase overexpression is associated with Leydig cell dysfunction in primary spermatogenic failure. | 1 |
| 33336383 | 2021 | A novel STS mutation and an Xp22.31 microdeletion in a Chinese family with X-linked ichthyosis. | 0 |
| 34675221 | 2021 | Steroid sulfatase deficiency causes cellular senescence and abnormal differentiation by inducing Yippee-like 3 expression in human keratinocytes. | 0 |
| 32005174 | 2020 | A novel nonsense mutation in the STS gene in a Pakistani family with X-linked recessive ichthyosis: including a very rare case of two homozygous female patients. | 1 |
Citation
Dessen P
STS (steroid sulfatase)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43814/sts
