Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SULT1A1 (sulfotransferase family 1A member 1)

Identity

Alias_namesSTP
STP1
sulfotransferase family
Alias_symbol (synonym)P-PST
Other aliasHAST1/HAST2
PST
ST1A1
ST1A3
TSPST1
HGNC (Hugo) SULT1A1
LocusID (NCBI) 6817
Atlas_Id 42449
Location 16p11.2  [Link to chromosome band 16p11]
Location_base_pair Starts at 28605587 and ends at 28610044 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SULT1A1   11453
Cards
Entrez_Gene (NCBI)SULT1A1  6817  sulfotransferase family 1A member 1
AliasesHAST1/HAST2; P-PST; PST; ST1A1; 
ST1A3; STP; STP1; TSPST1
GeneCards (Weizmann)SULT1A1
Ensembl hg19 (Hinxton)ENSG00000196502 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196502 [Gene_View]  chr16:28605587-28610044 [Contig_View]  SULT1A1 [Vega]
ICGC DataPortalENSG00000196502
TCGA cBioPortalSULT1A1
AceView (NCBI)SULT1A1
Genatlas (Paris)SULT1A1
WikiGenes6817
SOURCE (Princeton)SULT1A1
Genetics Home Reference (NIH)SULT1A1
Genomic and cartography
GoldenPath hg38 (UCSC)SULT1A1  -     chr16:28605587-28610044 -  16p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SULT1A1  -     16p11.2   [Description]    (hg19-Feb_2009)
EnsemblSULT1A1 - 16p11.2 [CytoView hg19]  SULT1A1 - 16p11.2 [CytoView hg38]
Mapping of homologs : NCBISULT1A1 [Mapview hg19]  SULT1A1 [Mapview hg38]
OMIM171150   
Gene and transcription
Genbank (Entrez)AB062428 AB209149 AJ007418 AL558375 BC000923
RefSeq transcript (Entrez)NM_001055 NM_177529 NM_177530 NM_177534 NM_177536
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SULT1A1
Cluster EST : UnigeneHs.736805 [ NCBI ]
CGAP (NCI)Hs.736805
Alternative Splicing GalleryENSG00000196502
Gene ExpressionSULT1A1 [ NCBI-GEO ]   SULT1A1 [ EBI - ARRAY_EXPRESS ]   SULT1A1 [ SEEK ]   SULT1A1 [ MEM ]
Gene Expression Viewer (FireBrowse)SULT1A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6817
GTEX Portal (Tissue expression)SULT1A1
Human Protein AtlasENSG00000196502-SULT1A1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP50225   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP50225  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP50225
Splice isoforms : SwissVarP50225
Catalytic activity : Enzyme2.8.2.1 [ Enzyme-Expasy ]   2.8.2.12.8.2.1 [ IntEnz-EBI ]   2.8.2.1 [ BRENDA ]   2.8.2.1 [ KEGG ]   
PhosPhoSitePlusP50225
Domains : Interpro (EBI)P-loop_NTPase    Sulfotransferase_dom   
Domain families : Pfam (Sanger)Sulfotransfer_1 (PF00685)   
Domain families : Pfam (NCBI)pfam00685   
Conserved Domain (NCBI)SULT1A1
DMDM Disease mutations6817
Blocks (Seattle)SULT1A1
PDB (SRS)1LS6    1Z28    2D06    3QVU    3QVV    3U3J    3U3K    3U3M    3U3O    3U3R    4GRA   
PDB (PDBSum)1LS6    1Z28    2D06    3QVU    3QVV    3U3J    3U3K    3U3M    3U3O    3U3R    4GRA   
PDB (IMB)1LS6    1Z28    2D06    3QVU    3QVV    3U3J    3U3K    3U3M    3U3O    3U3R    4GRA   
PDB (RSDB)1LS6    1Z28    2D06    3QVU    3QVV    3U3J    3U3K    3U3M    3U3O    3U3R    4GRA   
Structural Biology KnowledgeBase1LS6    1Z28    2D06    3QVU    3QVV    3U3J    3U3K    3U3M    3U3O    3U3R    4GRA   
SCOP (Structural Classification of Proteins)1LS6    1Z28    2D06    3QVU    3QVV    3U3J    3U3K    3U3M    3U3O    3U3R    4GRA   
CATH (Classification of proteins structures)1LS6    1Z28    2D06    3QVU    3QVV    3U3J    3U3K    3U3M    3U3O    3U3R    4GRA   
SuperfamilyP50225
Human Protein Atlas [tissue]ENSG00000196502-SULT1A1 [tissue]
Peptide AtlasP50225
HPRD01372
IPIIPI00654711   IPI00895850   IPI00300026   
Protein Interaction databases
DIP (DOE-UCLA)P50225
IntAct (EBI)P50225
FunCoupENSG00000196502
BioGRIDSULT1A1
STRING (EMBL)SULT1A1
ZODIACSULT1A1
Ontologies - Pathways
QuickGOP50225
Ontology : AmiGOaryl sulfotransferase activity  aryl sulfotransferase activity  protein binding  cytosol  ethanol catabolic process  catecholamine metabolic process  xenobiotic metabolic process  sulfotransferase activity  estrogen metabolic process  amine metabolic process  flavonoid metabolic process  flavonol 3-sulfotransferase activity  steroid sulfotransferase activity  3'-phosphoadenosine 5'-phosphosulfate metabolic process  3'-phosphoadenosine 5'-phosphosulfate metabolic process  sulfation  
Ontology : EGO-EBIaryl sulfotransferase activity  aryl sulfotransferase activity  protein binding  cytosol  ethanol catabolic process  catecholamine metabolic process  xenobiotic metabolic process  sulfotransferase activity  estrogen metabolic process  amine metabolic process  flavonoid metabolic process  flavonol 3-sulfotransferase activity  steroid sulfotransferase activity  3'-phosphoadenosine 5'-phosphosulfate metabolic process  3'-phosphoadenosine 5'-phosphosulfate metabolic process  sulfation  
Pathways : KEGGChemical carcinogenesis   
NDEx NetworkSULT1A1
Atlas of Cancer Signalling NetworkSULT1A1
Wikipedia pathwaysSULT1A1
Orthology - Evolution
OrthoDB6817
GeneTree (enSembl)ENSG00000196502
Phylogenetic Trees/Animal Genes : TreeFamSULT1A1
HOVERGENP50225
HOGENOMP50225
Homologs : HomoloGeneSULT1A1
Homology/Alignments : Family Browser (UCSC)SULT1A1
Gene fusions - Rearrangements
Tumor Fusion PortalSULT1A1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSULT1A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SULT1A1
dbVarSULT1A1
ClinVarSULT1A1
1000_GenomesSULT1A1 
Exome Variant ServerSULT1A1
ExAC (Exome Aggregation Consortium)ENSG00000196502
GNOMAD BrowserENSG00000196502
Genetic variants : HAPMAP6817
Genomic Variants (DGV)SULT1A1 [DGVbeta]
DECIPHERSULT1A1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSULT1A1 
Mutations
ICGC Data PortalSULT1A1 
TCGA Data PortalSULT1A1 
Broad Tumor PortalSULT1A1
OASIS PortalSULT1A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSULT1A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSULT1A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch SULT1A1
DgiDB (Drug Gene Interaction Database)SULT1A1
DoCM (Curated mutations)SULT1A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SULT1A1 (select a term)
intoGenSULT1A1
Cancer3DSULT1A1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM171150   
Orphanet
DisGeNETSULT1A1
MedgenSULT1A1
Genetic Testing Registry SULT1A1
NextProtP50225 [Medical]
TSGene6817
GENETestsSULT1A1
Target ValidationSULT1A1
Huge Navigator SULT1A1 [HugePedia]
snp3D : Map Gene to Disease6817
BioCentury BCIQSULT1A1
ClinGenSULT1A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6817
Chemical/Pharm GKB GenePA343
Clinical trialSULT1A1
Miscellaneous
canSAR (ICR)SULT1A1 (select the gene name)
Probes
Litterature
PubMed211 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSULT1A1
EVEXSULT1A1
GoPubMedSULT1A1
iHOPSULT1A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:37:12 CET 2017

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