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SUPT16H (SPT16 homolog, facilitates chromatin remodeling subunit)

Identity

Alias (NCBI)CDC68
FACTP140
SPT16
SPT16/CDC68
HGNC (Hugo) SUPT16H
HGNC Alias symbFACT
FACTP140
SPT16/CDC68
FLJ14010
FLJ10857
CDC68
HGNC Alias namefacilitates chromatin remodeling 140 kDa subunit
HGNC Previous namesuppressor of Ty (S.cerevisiae) 16 homolog
 suppressor of Ty 16 homolog (S. cerevisiae)
LocusID (NCBI) 11198
Atlas_Id 50177
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 21351476 and ends at 21384019 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CS (12q13.3) / SUPT16H (14q11.2)KMT2B (19q13.12) / SUPT16H (14q11.2)SUPT16H (14q11.2) / EMP2 (16p13.13)
VPS13C (15q22.2) / SUPT16H (14q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SUPT16H   11465
Cards
Entrez_Gene (NCBI)SUPT16H    SPT16 homolog, facilitates chromatin remodeling subunit
AliasesCDC68; FACTP140; SPT16; SPT16/CDC68
GeneCards (Weizmann)SUPT16H
Ensembl hg19 (Hinxton)ENSG00000092201 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000092201 [Gene_View]  ENSG00000092201 [Sequence]  chr14:21351476-21384019 [Contig_View]  SUPT16H [Vega]
ICGC DataPortalENSG00000092201
TCGA cBioPortalSUPT16H
AceView (NCBI)SUPT16H
Genatlas (Paris)SUPT16H
SOURCE (Princeton)SUPT16H
Genetics Home Reference (NIH)SUPT16H
Genomic and cartography
GoldenPath hg38 (UCSC)SUPT16H  -     chr14:21351476-21384019 -  14q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SUPT16H  -     14q11.2   [Description]    (hg19-Feb_2009)
GoldenPathSUPT16H - 14q11.2 [CytoView hg19]  SUPT16H - 14q11.2 [CytoView hg38]
ImmunoBaseENSG00000092201
Genome Data Viewer NCBISUPT16H [Mapview hg19]  
OMIM605012   
Gene and transcription
Genbank (Entrez)AF164924 AK001719 AK024072 AK091676 BC000565
RefSeq transcript (Entrez)NM_007192
Consensus coding sequences : CCDS (NCBI)SUPT16H
Gene ExpressionSUPT16H [ NCBI-GEO ]   SUPT16H [ EBI - ARRAY_EXPRESS ]   SUPT16H [ SEEK ]   SUPT16H [ MEM ]
Gene Expression Viewer (FireBrowse)SUPT16H [ Firebrowse - Broad ]
GenevisibleExpression of SUPT16H in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11198
GTEX Portal (Tissue expression)SUPT16H
Human Protein AtlasENSG00000092201-SUPT16H [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5B9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5B9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5B9
PhosPhoSitePlusQ9Y5B9
Domains : Interpro (EBI)Creatin/AminoP/Spt16_NTD    Creatinase/aminopeptidase-like    DUF1747    FACT-Spt16_Nlobe    FACT_Spt16    Pept_M24    PH-like_dom_sf    Spt16    Spt16_M24   
Domain families : Pfam (Sanger)FACT-Spt16_Nlob (PF14826)    Peptidase_M24 (PF00557)    Rtt106 (PF08512)    SPT16 (PF08644)   
Domain families : Pfam (NCBI)pfam14826    pfam00557    pfam08512    pfam08644   
Domain families : Smart (EMBL)FACT-Spt16_Nlob (SM01285)  Rtt106 (SM01287)  SPT16 (SM01286)  
Conserved Domain (NCBI)SUPT16H
PDB (RSDB)4Z2M    4Z2N    5E5B    5UMT    5UMU    5XM2    6UPK    6UPL   
PDB Europe4Z2M    4Z2N    5E5B    5UMT    5UMU    5XM2    6UPK    6UPL   
PDB (PDBSum)4Z2M    4Z2N    5E5B    5UMT    5UMU    5XM2    6UPK    6UPL   
PDB (IMB)4Z2M    4Z2N    5E5B    5UMT    5UMU    5XM2    6UPK    6UPL   
Structural Biology KnowledgeBase4Z2M    4Z2N    5E5B    5UMT    5UMU    5XM2    6UPK    6UPL   
SCOP (Structural Classification of Proteins)4Z2M    4Z2N    5E5B    5UMT    5UMU    5XM2    6UPK    6UPL   
CATH (Classification of proteins structures)4Z2M    4Z2N    5E5B    5UMT    5UMU    5XM2    6UPK    6UPL   
SuperfamilyQ9Y5B9
AlphaFold pdb e-kbQ9Y5B9   
Human Protein Atlas [tissue]ENSG00000092201-SUPT16H [tissue]
HPRD16088
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5B9
IntAct (EBI)Q9Y5B9
BioGRIDSUPT16H
STRING (EMBL)SUPT16H
ZODIACSUPT16H
Ontologies - Pathways
QuickGOQ9Y5B9
Ontology : AmiGORNA binding  protein binding  nucleoplasm  nucleoplasm  DNA replication  DNA repair  nucleosome disassembly  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  nucleosome binding  positive regulation of DNA-templated transcription, elongation  positive regulation of transcription elongation from RNA polymerase II promoter  DNA replication-independent nucleosome organization  FACT complex  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBIRNA binding  protein binding  nucleoplasm  nucleoplasm  DNA replication  DNA repair  nucleosome disassembly  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  nucleosome binding  positive regulation of DNA-templated transcription, elongation  positive regulation of transcription elongation from RNA polymerase II promoter  DNA replication-independent nucleosome organization  FACT complex  regulation of signal transduction by p53 class mediator  
Pathways : BIOCARTAControl of Gene Expression by Vitamin D Receptor [Genes]   
NDEx NetworkSUPT16H
Atlas of Cancer Signalling NetworkSUPT16H
Wikipedia pathwaysSUPT16H
Orthology - Evolution
OrthoDB11198
GeneTree (enSembl)ENSG00000092201
Phylogenetic Trees/Animal Genes : TreeFamSUPT16H
Homologs : HomoloGeneSUPT16H
Homology/Alignments : Family Browser (UCSC)SUPT16H
Gene fusions - Rearrangements
Fusion : QuiverSUPT16H
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSUPT16H [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SUPT16H
dbVarSUPT16H
ClinVarSUPT16H
MonarchSUPT16H
1000_GenomesSUPT16H 
Exome Variant ServerSUPT16H
GNOMAD BrowserENSG00000092201
Varsome BrowserSUPT16H
ACMGSUPT16H variants
VarityQ9Y5B9
Genomic Variants (DGV)SUPT16H [DGVbeta]
DECIPHERSUPT16H [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSUPT16H 
Mutations
ICGC Data PortalSUPT16H 
TCGA Data PortalSUPT16H 
Broad Tumor PortalSUPT16H
OASIS PortalSUPT16H [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSUPT16H  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSUPT16H
Mutations and Diseases : HGMDSUPT16H
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSUPT16H
DgiDB (Drug Gene Interaction Database)SUPT16H
DoCM (Curated mutations)SUPT16H
CIViC (Clinical Interpretations of Variants in Cancer)SUPT16H
Cancer3DSUPT16H
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605012   
Orphanet
DisGeNETSUPT16H
MedgenSUPT16H
Genetic Testing Registry SUPT16H
NextProtQ9Y5B9 [Medical]
GENETestsSUPT16H
Target ValidationSUPT16H
Huge Navigator SUPT16H [HugePedia]
ClinGenSUPT16H (curated)
Clinical trials, drugs, therapy
MyCancerGenomeSUPT16H
Protein Interactions : CTDSUPT16H
Pharm GKB GenePA36251
PharosQ9Y5B9
Clinical trialSUPT16H
Miscellaneous
canSAR (ICR)SUPT16H
HarmonizomeSUPT16H
DataMed IndexSUPT16H
Probes
Litterature
PubMed159 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSUPT16H
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:33:52 CEST 2021

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