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TADA3 (transcriptional adaptor 3)

Identity

Alias_namesTADA3L
transcriptional adaptor 3 (NGG1 homolog
Alias_symbol (synonym)FLJ20221
FLJ21329
ADA3
hADA3
NGG1
Other aliasSTAF54
HGNC (Hugo) TADA3
LocusID (NCBI) 10474
Atlas_Id 51166
Location 3p25.3  [Link to chromosome band 3p25]
Location_base_pair Starts at 9779964 and ends at 9793011 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATP5J (21q21.3) / TADA3 (3p25.3)PCSK1 (5q15) / TADA3 (3p25.3)RYBP (3p13) / TADA3 (3p25.3)
TADA3 (3p25.3) / GRAMD1C (3q13.31)RYBP 3p13 / TADA3 3p25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TADA3   19422
Cards
Entrez_Gene (NCBI)TADA3  10474  transcriptional adaptor 3
AliasesADA3; NGG1; STAF54; TADA3L; 
hADA3
GeneCards (Weizmann)TADA3
Ensembl hg19 (Hinxton)ENSG00000171148 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171148 [Gene_View]  chr3:9779964-9793011 [Contig_View]  TADA3 [Vega]
ICGC DataPortalENSG00000171148
TCGA cBioPortalTADA3
AceView (NCBI)TADA3
Genatlas (Paris)TADA3
WikiGenes10474
SOURCE (Princeton)TADA3
Genetics Home Reference (NIH)TADA3
Genomic and cartography
GoldenPath hg38 (UCSC)TADA3  -     chr3:9779964-9793011 -  3p25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TADA3  -     3p25.3   [Description]    (hg19-Feb_2009)
EnsemblTADA3 - 3p25.3 [CytoView hg19]  TADA3 - 3p25.3 [CytoView hg38]
Mapping of homologs : NCBITADA3 [Mapview hg19]  TADA3 [Mapview hg38]
OMIM602945   
Gene and transcription
Genbank (Entrez)AA602644 AF069733 AK000228 AK024982 AK292264
RefSeq transcript (Entrez)NM_001278270 NM_006354 NM_133480 NM_133481
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TADA3
Cluster EST : UnigeneHs.386390 [ NCBI ]
CGAP (NCI)Hs.386390
Alternative Splicing GalleryENSG00000171148
Gene ExpressionTADA3 [ NCBI-GEO ]   TADA3 [ EBI - ARRAY_EXPRESS ]   TADA3 [ SEEK ]   TADA3 [ MEM ]
Gene Expression Viewer (FireBrowse)TADA3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10474
GTEX Portal (Tissue expression)TADA3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75528   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75528  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75528
Splice isoforms : SwissVarO75528
PhosPhoSitePlusO75528
Domains : Interpro (EBI)Histone_AcTrfase_su3   
Domain families : Pfam (Sanger)Ada3 (PF10198)   
Domain families : Pfam (NCBI)pfam10198   
Conserved Domain (NCBI)TADA3
DMDM Disease mutations10474
Blocks (Seattle)TADA3
SuperfamilyO75528
Human Protein AtlasENSG00000171148
Peptide AtlasO75528
HPRD04252
IPIIPI00220486   IPI00375534   IPI00927551   
Protein Interaction databases
DIP (DOE-UCLA)O75528
IntAct (EBI)O75528
FunCoupENSG00000171148
BioGRIDTADA3
STRING (EMBL)TADA3
ZODIACTADA3
Ontologies - Pathways
QuickGOO75528
Ontology : AmiGOSAGA complex  regulation of protein phosphorylation  transcription factor activity, sequence-specific DNA binding  transcription coactivator activity  histone acetyltransferase activity  protein binding  intracellular  nucleus  nucleoplasm  nucleoplasm  Ada2/Gcn5/Ada3 transcription activator complex  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  positive regulation of gene expression  protein deubiquitination  ligand-dependent nuclear receptor binding  protein domain specific binding  ligand-dependent nuclear receptor transcription coactivator activity  intracellular estrogen receptor signaling pathway  STAGA complex  regulation of histone deacetylation  regulation of protein stability  transcription factor TFTC complex  thiol-dependent ubiquitinyl hydrolase activity  histone H3 acetylation  histone H4 acetylation  positive regulation of transcription, DNA-templated  mitotic spindle  regulation of tubulin deacetylation  
Ontology : EGO-EBISAGA complex  regulation of protein phosphorylation  transcription factor activity, sequence-specific DNA binding  transcription coactivator activity  histone acetyltransferase activity  protein binding  intracellular  nucleus  nucleoplasm  nucleoplasm  Ada2/Gcn5/Ada3 transcription activator complex  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  positive regulation of gene expression  protein deubiquitination  ligand-dependent nuclear receptor binding  protein domain specific binding  ligand-dependent nuclear receptor transcription coactivator activity  intracellular estrogen receptor signaling pathway  STAGA complex  regulation of histone deacetylation  regulation of protein stability  transcription factor TFTC complex  thiol-dependent ubiquitinyl hydrolase activity  histone H3 acetylation  histone H4 acetylation  positive regulation of transcription, DNA-templated  mitotic spindle  regulation of tubulin deacetylation  
NDEx NetworkTADA3
Atlas of Cancer Signalling NetworkTADA3
Wikipedia pathwaysTADA3
Orthology - Evolution
OrthoDB10474
GeneTree (enSembl)ENSG00000171148
Phylogenetic Trees/Animal Genes : TreeFamTADA3
HOVERGENO75528
HOGENOMO75528
Homologs : HomoloGeneTADA3
Homology/Alignments : Family Browser (UCSC)TADA3
Gene fusions - Rearrangements
Fusion : MitelmanRYBP/TADA3 [3p13/3p25.3]  [t(3;3)(p13;p25)]  
Fusion: TCGARYBP 3p13 TADA3 3p25.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTADA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TADA3
dbVarTADA3
ClinVarTADA3
1000_GenomesTADA3 
Exome Variant ServerTADA3
ExAC (Exome Aggregation Consortium)TADA3 (select the gene name)
Genetic variants : HAPMAP10474
Genomic Variants (DGV)TADA3 [DGVbeta]
DECIPHERTADA3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTADA3 
Mutations
ICGC Data PortalTADA3 
TCGA Data PortalTADA3 
Broad Tumor PortalTADA3
OASIS PortalTADA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTADA3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTADA3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TADA3
DgiDB (Drug Gene Interaction Database)TADA3
DoCM (Curated mutations)TADA3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TADA3 (select a term)
intoGenTADA3
Cancer3DTADA3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602945   
Orphanet
MedgenTADA3
Genetic Testing Registry TADA3
NextProtO75528 [Medical]
TSGene10474
GENETestsTADA3
Target ValidationTADA3
Huge Navigator TADA3 [HugePedia]
snp3D : Map Gene to Disease10474
BioCentury BCIQTADA3
ClinGenTADA3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10474
Chemical/Pharm GKB GenePA165698494
Clinical trialTADA3
Miscellaneous
canSAR (ICR)TADA3 (select the gene name)
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTADA3
EVEXTADA3
GoPubMedTADA3
iHOPTADA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:16:19 CEST 2017

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