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TADA3 (transcriptional adaptor 3)

Identity

Alias (NCBI)ADA3
NGG1
STAF54
TADA3L
hADA3
HGNC (Hugo) TADA3
HGNC Alias symbFLJ20221
FLJ21329
ADA3
hADA3
NGG1
HGNC Alias namealteration/deficiency in activation 3
HGNC Previous nameTADA3L
HGNC Previous nametranscriptional adaptor 3 (NGG1 homolog, yeast)-like
LocusID (NCBI) 10474
Atlas_Id 51166
Location 3p25.3  [Link to chromosome band 3p25]
Location_base_pair Starts at 9783128 and ends at 9793011 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATP5J (21q21.3) / TADA3 (3p25.3)PCSK1 (5q15) / TADA3 (3p25.3)RYBP (3p13) / TADA3 (3p25.3)
TADA3 (3p25.3) / GRAMD1C (3q13.31)RYBP 3p13 / TADA3 3p25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TADA3   19422
Cards
Entrez_Gene (NCBI)TADA3    transcriptional adaptor 3
AliasesADA3; NGG1; STAF54; TADA3L; 
hADA3
GeneCards (Weizmann)TADA3
Ensembl hg19 (Hinxton)ENSG00000171148 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171148 [Gene_View]  ENSG00000171148 [Sequence]  chr3:9783128-9793011 [Contig_View]  TADA3 [Vega]
ICGC DataPortalENSG00000171148
TCGA cBioPortalTADA3
AceView (NCBI)TADA3
Genatlas (Paris)TADA3
SOURCE (Princeton)TADA3
Genetics Home Reference (NIH)TADA3
Genomic and cartography
GoldenPath hg38 (UCSC)TADA3  -     chr3:9783128-9793011 -  3p25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TADA3  -     3p25.3   [Description]    (hg19-Feb_2009)
GoldenPathTADA3 - 3p25.3 [CytoView hg19]  TADA3 - 3p25.3 [CytoView hg38]
ImmunoBaseENSG00000171148
Genome Data Viewer NCBITADA3 [Mapview hg19]  
OMIM602945   
Gene and transcription
Genbank (Entrez)AA602644 AF069733 AK000228 AK024982 AK292264
RefSeq transcript (Entrez)NM_001278270 NM_006354 NM_133480 NM_133481
Consensus coding sequences : CCDS (NCBI)TADA3
Gene ExpressionTADA3 [ NCBI-GEO ]   TADA3 [ EBI - ARRAY_EXPRESS ]   TADA3 [ SEEK ]   TADA3 [ MEM ]
Gene Expression Viewer (FireBrowse)TADA3 [ Firebrowse - Broad ]
GenevisibleExpression of TADA3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10474
GTEX Portal (Tissue expression)TADA3
Human Protein AtlasENSG00000171148-TADA3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75528   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75528  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75528
PhosPhoSitePlusO75528
Domains : Interpro (EBI)Histone_AcTrfase_su3   
Domain families : Pfam (Sanger)Ada3 (PF10198)   
Domain families : Pfam (NCBI)pfam10198   
Conserved Domain (NCBI)TADA3
SuperfamilyO75528
AlphaFold pdb e-kbO75528   
Human Protein Atlas [tissue]ENSG00000171148-TADA3 [tissue]
HPRD04252
Protein Interaction databases
DIP (DOE-UCLA)O75528
IntAct (EBI)O75528
BioGRIDTADA3
STRING (EMBL)TADA3
ZODIACTADA3
Ontologies - Pathways
QuickGOO75528
Ontology : AmiGOSAGA complex  mitotic cell cycle  regulation of protein phosphorylation  transcription coactivator activity  transcription coactivator activity  histone acetyltransferase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  Ada2/Gcn5/Ada3 transcription activator complex  Ada2/Gcn5/Ada3 transcription activator complex  regulation of transcription by RNA polymerase II  positive regulation of gene expression  protein deubiquitination  nuclear receptor binding  protein domain specific binding  nuclear receptor coactivator activity  intracellular estrogen receptor signaling pathway  STAGA complex  regulation of histone deacetylation  regulation of protein stability  transcription factor TFTC complex  histone H3 acetylation  histone H3 acetylation  histone H4 acetylation  positive regulation of transcription, DNA-templated  mitotic spindle  regulation of tubulin deacetylation  
Ontology : EGO-EBISAGA complex  mitotic cell cycle  regulation of protein phosphorylation  transcription coactivator activity  transcription coactivator activity  histone acetyltransferase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  Ada2/Gcn5/Ada3 transcription activator complex  Ada2/Gcn5/Ada3 transcription activator complex  regulation of transcription by RNA polymerase II  positive regulation of gene expression  protein deubiquitination  nuclear receptor binding  protein domain specific binding  nuclear receptor coactivator activity  intracellular estrogen receptor signaling pathway  STAGA complex  regulation of histone deacetylation  regulation of protein stability  transcription factor TFTC complex  histone H3 acetylation  histone H3 acetylation  histone H4 acetylation  positive regulation of transcription, DNA-templated  mitotic spindle  regulation of tubulin deacetylation  
NDEx NetworkTADA3
Atlas of Cancer Signalling NetworkTADA3
Wikipedia pathwaysTADA3
Orthology - Evolution
OrthoDB10474
GeneTree (enSembl)ENSG00000171148
Phylogenetic Trees/Animal Genes : TreeFamTADA3
Homologs : HomoloGeneTADA3
Homology/Alignments : Family Browser (UCSC)TADA3
Gene fusions - Rearrangements
Fusion : MitelmanRYBP/TADA3 [3p13/3p25.3]  
Fusion : QuiverTADA3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTADA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TADA3
dbVarTADA3
ClinVarTADA3
MonarchTADA3
1000_GenomesTADA3 
Exome Variant ServerTADA3
GNOMAD BrowserENSG00000171148
Varsome BrowserTADA3
ACMGTADA3 variants
VarityO75528
Genomic Variants (DGV)TADA3 [DGVbeta]
DECIPHERTADA3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTADA3 
Mutations
ICGC Data PortalTADA3 
TCGA Data PortalTADA3 
Broad Tumor PortalTADA3
OASIS PortalTADA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTADA3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTADA3
Mutations and Diseases : HGMDTADA3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTADA3
DgiDB (Drug Gene Interaction Database)TADA3
DoCM (Curated mutations)TADA3
CIViC (Clinical Interpretations of Variants in Cancer)TADA3
Cancer3DTADA3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602945   
Orphanet
DisGeNETTADA3
MedgenTADA3
Genetic Testing Registry TADA3
NextProtO75528 [Medical]
GENETestsTADA3
Target ValidationTADA3
Huge Navigator TADA3 [HugePedia]
ClinGenTADA3
Clinical trials, drugs, therapy
MyCancerGenomeTADA3
Protein Interactions : CTDTADA3
Pharm GKB GenePA165698494
PharosO75528
Clinical trialTADA3
Miscellaneous
canSAR (ICR)TADA3
HarmonizomeTADA3
DataMed IndexTADA3
Probes
Litterature
PubMed87 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTADA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:34:09 CEST 2021

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