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TM4SF1 (transmembrane 4 L six family member 1)

Identity

Alias (NCBI)H-L6
L6
M3S1
TAAL6
HGNC (Hugo) TM4SF1
HGNC Alias symbL6
HGNC Previous nameM3S1
HGNC Previous nametransmembrane 4 superfamily member 1
LocusID (NCBI) 4071
Atlas_Id 42583
Location 3q25.1  [Link to chromosome band 3q25]
Location_base_pair Starts at 149369022 and ends at 149377649 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MIDN (19p13.3) / TM4SF1 (3q25.1)NKX2-2 (20p11.22) / TM4SF1 (3q25.1)TM4SF1 (3q25.1) / ADGRB3 (6q12)
TM4SF1 (3q25.1) / TM4SF1 (3q25.1)UBA52 (19p13.11) / TM4SF1 (3q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TM4SF1   11853
Cards
Entrez_Gene (NCBI)TM4SF1    transmembrane 4 L six family member 1
AliasesH-L6; L6; M3S1; TAAL6
GeneCards (Weizmann)TM4SF1
Ensembl hg19 (Hinxton)ENSG00000169908 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169908 [Gene_View]  ENSG00000169908 [Sequence]  chr3:149369022-149377649 [Contig_View]  TM4SF1 [Vega]
ICGC DataPortalENSG00000169908
TCGA cBioPortalTM4SF1
AceView (NCBI)TM4SF1
Genatlas (Paris)TM4SF1
SOURCE (Princeton)TM4SF1
Genetics Home Reference (NIH)TM4SF1
Genomic and cartography
GoldenPath hg38 (UCSC)TM4SF1  -     chr3:149369022-149377649 -  3q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TM4SF1  -     3q25.1   [Description]    (hg19-Feb_2009)
GoldenPathTM4SF1 - 3q25.1 [CytoView hg19]  TM4SF1 - 3q25.1 [CytoView hg38]
ImmunoBaseENSG00000169908
Genome Data Viewer NCBITM4SF1 [Mapview hg19]  
OMIM191155   
Gene and transcription
Genbank (Entrez)AK093829 AK130073 AK130271 AL832780 BC008442
RefSeq transcript (Entrez)NM_014220
Consensus coding sequences : CCDS (NCBI)TM4SF1
Gene ExpressionTM4SF1 [ NCBI-GEO ]   TM4SF1 [ EBI - ARRAY_EXPRESS ]   TM4SF1 [ SEEK ]   TM4SF1 [ MEM ]
Gene Expression Viewer (FireBrowse)TM4SF1 [ Firebrowse - Broad ]
GenevisibleExpression of TM4SF1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4071
GTEX Portal (Tissue expression)TM4SF1
Human Protein AtlasENSG00000169908-TM4SF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30408   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30408  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30408
PhosPhoSitePlusP30408
Domains : Interpro (EBI)L6_membrane   
Domain families : Pfam (Sanger)L6_membrane (PF05805)   
Domain families : Pfam (NCBI)pfam05805   
Conserved Domain (NCBI)TM4SF1
SuperfamilyP30408
AlphaFold pdb e-kbP30408   
Human Protein Atlas [tissue]ENSG00000169908-TM4SF1 [tissue]
HPRD01854
Protein Interaction databases
DIP (DOE-UCLA)P30408
IntAct (EBI)P30408
BioGRIDTM4SF1
STRING (EMBL)TM4SF1
ZODIACTM4SF1
Ontologies - Pathways
QuickGOP30408
Ontology : AmiGOmolecular_function  protein binding  integral component of plasma membrane  biological_process  integral component of membrane  
Ontology : EGO-EBImolecular_function  protein binding  integral component of plasma membrane  biological_process  integral component of membrane  
NDEx NetworkTM4SF1
Atlas of Cancer Signalling NetworkTM4SF1
Wikipedia pathwaysTM4SF1
Orthology - Evolution
OrthoDB4071
GeneTree (enSembl)ENSG00000169908
Phylogenetic Trees/Animal Genes : TreeFamTM4SF1
Homologs : HomoloGeneTM4SF1
Homology/Alignments : Family Browser (UCSC)TM4SF1
Gene fusions - Rearrangements
Fusion Cancer (Beijing)NKX2-2 [20p11.22]  -  TM4SF1 [3q25.1]  [FUSC002464]
Fusion : QuiverTM4SF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTM4SF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TM4SF1
dbVarTM4SF1
ClinVarTM4SF1
MonarchTM4SF1
1000_GenomesTM4SF1 
Exome Variant ServerTM4SF1
GNOMAD BrowserENSG00000169908
Varsome BrowserTM4SF1
ACMGTM4SF1 variants
VarityP30408
Genomic Variants (DGV)TM4SF1 [DGVbeta]
DECIPHERTM4SF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTM4SF1 
Mutations
ICGC Data PortalTM4SF1 
TCGA Data PortalTM4SF1 
Broad Tumor PortalTM4SF1
OASIS PortalTM4SF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTM4SF1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTM4SF1
Mutations and Diseases : HGMDTM4SF1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTM4SF1
DgiDB (Drug Gene Interaction Database)TM4SF1
DoCM (Curated mutations)TM4SF1
CIViC (Clinical Interpretations of Variants in Cancer)TM4SF1
Cancer3DTM4SF1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM191155   
Orphanet
DisGeNETTM4SF1
MedgenTM4SF1
Genetic Testing Registry TM4SF1
NextProtP30408 [Medical]
GENETestsTM4SF1
Target ValidationTM4SF1
Huge Navigator TM4SF1 [HugePedia]
ClinGenTM4SF1
Clinical trials, drugs, therapy
MyCancerGenomeTM4SF1
Protein Interactions : CTDTM4SF1
Pharm GKB GenePA36554
PharosP30408
Clinical trialTM4SF1
Miscellaneous
canSAR (ICR)TM4SF1
HarmonizomeTM4SF1
DataMed IndexTM4SF1
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTM4SF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:35:16 CEST 2021

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