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TM4SF1 (transmembrane 4 L six family member 1)

Identity

Alias_namesM3S1
transmembrane 4 superfamily member 1
Alias_symbol (synonym)L6
Other aliasH-L6
TAAL6
HGNC (Hugo) TM4SF1
LocusID (NCBI) 4071
Atlas_Id 42583
Location 3q25.1  [Link to chromosome band 3q25]
Location_base_pair Starts at 149369018 and ends at 149377781 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MIDN (19p13.3) / TM4SF1 (3q25.1)NKX2-2 (20p11.22) / TM4SF1 (3q25.1)TM4SF1 (3q25.1) / ADGRB3 (6q12)
TM4SF1 (3q25.1) / TM4SF1 (3q25.1)UBA52 (19p13.11) / TM4SF1 (3q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TM4SF1   11853
Cards
Entrez_Gene (NCBI)TM4SF1  4071  transmembrane 4 L six family member 1
AliasesH-L6; L6; M3S1; TAAL6
GeneCards (Weizmann)TM4SF1
Ensembl hg19 (Hinxton)ENSG00000169908 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169908 [Gene_View]  chr3:149369018-149377781 [Contig_View]  TM4SF1 [Vega]
ICGC DataPortalENSG00000169908
TCGA cBioPortalTM4SF1
AceView (NCBI)TM4SF1
Genatlas (Paris)TM4SF1
WikiGenes4071
SOURCE (Princeton)TM4SF1
Genetics Home Reference (NIH)TM4SF1
Genomic and cartography
GoldenPath hg38 (UCSC)TM4SF1  -     chr3:149369018-149377781 -  3q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TM4SF1  -     3q25.1   [Description]    (hg19-Feb_2009)
EnsemblTM4SF1 - 3q25.1 [CytoView hg19]  TM4SF1 - 3q25.1 [CytoView hg38]
Mapping of homologs : NCBITM4SF1 [Mapview hg19]  TM4SF1 [Mapview hg38]
OMIM191155   
Gene and transcription
Genbank (Entrez)AK093829 AK130073 AK130271 AL832780 BC008442
RefSeq transcript (Entrez)NM_014220
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TM4SF1
Cluster EST : UnigeneHs.351316 [ NCBI ]
CGAP (NCI)Hs.351316
Alternative Splicing GalleryENSG00000169908
Gene ExpressionTM4SF1 [ NCBI-GEO ]   TM4SF1 [ EBI - ARRAY_EXPRESS ]   TM4SF1 [ SEEK ]   TM4SF1 [ MEM ]
Gene Expression Viewer (FireBrowse)TM4SF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4071
GTEX Portal (Tissue expression)TM4SF1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30408   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30408  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30408
Splice isoforms : SwissVarP30408
PhosPhoSitePlusP30408
Domains : Interpro (EBI)L6_membrane   
Domain families : Pfam (Sanger)L6_membrane (PF05805)   
Domain families : Pfam (NCBI)pfam05805   
Conserved Domain (NCBI)TM4SF1
DMDM Disease mutations4071
Blocks (Seattle)TM4SF1
SuperfamilyP30408
Human Protein AtlasENSG00000169908
Peptide AtlasP30408
HPRD01854
IPIIPI00744287   IPI00026520   IPI00798263   IPI00796433   IPI00797540   
Protein Interaction databases
DIP (DOE-UCLA)P30408
IntAct (EBI)P30408
FunCoupENSG00000169908
BioGRIDTM4SF1
STRING (EMBL)TM4SF1
ZODIACTM4SF1
Ontologies - Pathways
QuickGOP30408
Ontology : AmiGOmolecular_function  integral component of plasma membrane  biological_process  
Ontology : EGO-EBImolecular_function  integral component of plasma membrane  biological_process  
NDEx NetworkTM4SF1
Atlas of Cancer Signalling NetworkTM4SF1
Wikipedia pathwaysTM4SF1
Orthology - Evolution
OrthoDB4071
GeneTree (enSembl)ENSG00000169908
Phylogenetic Trees/Animal Genes : TreeFamTM4SF1
HOVERGENP30408
HOGENOMP30408
Homologs : HomoloGeneTM4SF1
Homology/Alignments : Family Browser (UCSC)TM4SF1
Gene fusions - Rearrangements
Fusion Cancer (Beijing)NKX2-2 [20p11.22]  -  TM4SF1 [3q25.1]  [FUSC002464]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTM4SF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TM4SF1
dbVarTM4SF1
ClinVarTM4SF1
1000_GenomesTM4SF1 
Exome Variant ServerTM4SF1
ExAC (Exome Aggregation Consortium)TM4SF1 (select the gene name)
Genetic variants : HAPMAP4071
Genomic Variants (DGV)TM4SF1 [DGVbeta]
DECIPHERTM4SF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTM4SF1 
Mutations
ICGC Data PortalTM4SF1 
TCGA Data PortalTM4SF1 
Broad Tumor PortalTM4SF1
OASIS PortalTM4SF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTM4SF1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTM4SF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TM4SF1
DgiDB (Drug Gene Interaction Database)TM4SF1
DoCM (Curated mutations)TM4SF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TM4SF1 (select a term)
intoGenTM4SF1
Cancer3DTM4SF1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM191155   
Orphanet
MedgenTM4SF1
Genetic Testing Registry TM4SF1
NextProtP30408 [Medical]
TSGene4071
GENETestsTM4SF1
Target ValidationTM4SF1
Huge Navigator TM4SF1 [HugePedia]
snp3D : Map Gene to Disease4071
BioCentury BCIQTM4SF1
ClinGenTM4SF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4071
Chemical/Pharm GKB GenePA36554
Clinical trialTM4SF1
Miscellaneous
canSAR (ICR)TM4SF1 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTM4SF1
EVEXTM4SF1
GoPubMedTM4SF1
iHOPTM4SF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:59:33 CEST 2017

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