TMF1 (TATA element modulatory factor 1)

2003-08-01  

Identity

HGNC
TMF1
LOCATION
3p14.1
LOCUSID
7110
ALIAS
ARA160,TMF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7110
MIM: 601126
HGNC: 11870
Ensembl: ENSG00000144747

Variants:

dbSNP: 7110
ClinVar: 7110
TCGA: ENSG00000144747
COSMIC: TMF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144747ENST00000398559P82094
ENSG00000144747ENST00000398559A0A024R370
ENSG00000144747ENST00000488010F8WF45
ENSG00000144747ENST00000646304A0A2R8Y7M0
ENSG00000144747ENST00000646708P82094

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Retrograde transport at the Trans-Golgi-NetworkREACTOMER-HSA-6811440

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
232398822013Molecular insights into vesicle tethering at the Golgi by the conserved oligomeric Golgi (COG) complex and the golgin TATA element modulatory factor (TMF).40
176980612007Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic.25
244781912014Primary immunodeficiency caused by an exonized retroposed gene copy inserted in the CYBB gene.14
193308322009TMF/ARA160 downregulates proangiogenic genes and attenuates the progression of PC3 xenografts.6
295453702018PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1.3

Citation

Dessen P

TMF1 (TATA element modulatory factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/42590/tmf1