Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TNFRSF10C (TNF receptor superfamily member 10c)

Identity

Alias_namestumor necrosis factor receptor superfamily
Alias_symbol (synonym)DcR1
TRAILR3
LIT
TRID
CD263
Other aliasDCR1
DCR1-TNFR
TRAIL-R3
HGNC (Hugo) TNFRSF10C
LocusID (NCBI) 8794
Atlas_Id 42607
Location 8p21.3  [Link to chromosome band 8p21]
Location_base_pair Starts at 23102814 and ends at 23117437 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AMMECR1L (2q14.3) / TNFRSF10C (8p21.3)NUCKS1 (1q32.1) / TNFRSF10C (8p21.3)AMMECR1L 2q14.3 / TNFRSF10C 8p21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TNFRSF10C   11906
Cards
Entrez_Gene (NCBI)TNFRSF10C  8794  TNF receptor superfamily member 10c
AliasesCD263; DCR1; DCR1-TNFR; LIT; 
TRAIL-R3; TRAILR3; TRID
GeneCards (Weizmann)TNFRSF10C
Ensembl hg19 (Hinxton)ENSG00000173535 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173535 [Gene_View]  chr8:23102814-23117437 [Contig_View]  TNFRSF10C [Vega]
ICGC DataPortalENSG00000173535
TCGA cBioPortalTNFRSF10C
AceView (NCBI)TNFRSF10C
Genatlas (Paris)TNFRSF10C
WikiGenes8794
SOURCE (Princeton)TNFRSF10C
Genetics Home Reference (NIH)TNFRSF10C
Genomic and cartography
GoldenPath hg38 (UCSC)TNFRSF10C  -     chr8:23102814-23117437 +  8p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TNFRSF10C  -     8p21.3   [Description]    (hg19-Feb_2009)
EnsemblTNFRSF10C - 8p21.3 [CytoView hg19]  TNFRSF10C - 8p21.3 [CytoView hg38]
Mapping of homologs : NCBITNFRSF10C [Mapview hg19]  TNFRSF10C [Mapview hg38]
OMIM603613   
Gene and transcription
Genbank (Entrez)AF012536 AF012629 AF014794 AF016267 AF020502
RefSeq transcript (Entrez)NM_003841
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TNFRSF10C
Cluster EST : UnigeneHs.655801 [ NCBI ]
CGAP (NCI)Hs.655801
Alternative Splicing GalleryENSG00000173535
Gene ExpressionTNFRSF10C [ NCBI-GEO ]   TNFRSF10C [ EBI - ARRAY_EXPRESS ]   TNFRSF10C [ SEEK ]   TNFRSF10C [ MEM ]
Gene Expression Viewer (FireBrowse)TNFRSF10C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8794
GTEX Portal (Tissue expression)TNFRSF10C
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14798   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14798  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14798
Splice isoforms : SwissVarO14798
PhosPhoSitePlusO14798
Domaine pattern : Prosite (Expaxy)TNFR_NGFR_1 (PS00652)    TNFR_NGFR_2 (PS50050)   
Domains : Interpro (EBI)TNFR/NGFR_Cys_rich_reg    TNFR_10    TNFRSF10_N   
Domain families : Pfam (Sanger)TNFR_c6 (PF00020)   
Domain families : Pfam (NCBI)pfam00020   
Domain families : Smart (EMBL)TNFR (SM00208)  
Conserved Domain (NCBI)TNFRSF10C
DMDM Disease mutations8794
Blocks (Seattle)TNFRSF10C
SuperfamilyO14798
Human Protein AtlasENSG00000173535
Peptide AtlasO14798
HPRD04681
Protein Interaction databases
DIP (DOE-UCLA)O14798
IntAct (EBI)O14798
FunCoupENSG00000173535
BioGRIDTNFRSF10C
STRING (EMBL)TNFRSF10C
ZODIACTNFRSF10C
Ontologies - Pathways
QuickGOO14798
Ontology : AmiGOtransmembrane signaling receptor activity  tumor necrosis factor-activated receptor activity  plasma membrane  integral component of plasma membrane  inflammatory response  immune response  signal transduction  multicellular organism development  anchored component of membrane  response to lipopolysaccharide  tumor necrosis factor-mediated signaling pathway  regulation of cell proliferation  regulation of apoptotic process  regulation of apoptotic process  TRAIL binding  apoptotic signaling pathway  
Ontology : EGO-EBItransmembrane signaling receptor activity  tumor necrosis factor-activated receptor activity  plasma membrane  integral component of plasma membrane  inflammatory response  immune response  signal transduction  multicellular organism development  anchored component of membrane  response to lipopolysaccharide  tumor necrosis factor-mediated signaling pathway  regulation of cell proliferation  regulation of apoptotic process  regulation of apoptotic process  TRAIL binding  apoptotic signaling pathway  
Pathways : KEGGCytokine-cytokine receptor interaction    Apoptosis    Natural killer cell mediated cytotoxicity    Measles    Influenza A   
NDEx NetworkTNFRSF10C
Atlas of Cancer Signalling NetworkTNFRSF10C
Wikipedia pathwaysTNFRSF10C
Orthology - Evolution
OrthoDB8794
GeneTree (enSembl)ENSG00000173535
Phylogenetic Trees/Animal Genes : TreeFamTNFRSF10C
HOVERGENO14798
HOGENOMO14798
Homologs : HomoloGeneTNFRSF10C
Homology/Alignments : Family Browser (UCSC)TNFRSF10C
Gene fusions - Rearrangements
Fusion : MitelmanAMMECR1L/TNFRSF10C [2q14.3/8p21.3]  [t(2;8)(q14;p21)]  
Fusion: TCGAAMMECR1L 2q14.3 TNFRSF10C 8p21.3 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNFRSF10C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNFRSF10C
dbVarTNFRSF10C
ClinVarTNFRSF10C
1000_GenomesTNFRSF10C 
Exome Variant ServerTNFRSF10C
ExAC (Exome Aggregation Consortium)TNFRSF10C (select the gene name)
Genetic variants : HAPMAP8794
Genomic Variants (DGV)TNFRSF10C [DGVbeta]
DECIPHERTNFRSF10C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTNFRSF10C 
Mutations
ICGC Data PortalTNFRSF10C 
TCGA Data PortalTNFRSF10C 
Broad Tumor PortalTNFRSF10C
OASIS PortalTNFRSF10C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNFRSF10C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTNFRSF10C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Death Receptor Database (DRdb)
BioMutasearch TNFRSF10C
DgiDB (Drug Gene Interaction Database)TNFRSF10C
DoCM (Curated mutations)TNFRSF10C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TNFRSF10C (select a term)
intoGenTNFRSF10C
Cancer3DTNFRSF10C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603613   
Orphanet
MedgenTNFRSF10C
Genetic Testing Registry TNFRSF10C
NextProtO14798 [Medical]
TSGene8794
GENETestsTNFRSF10C
Target ValidationTNFRSF10C
Huge Navigator TNFRSF10C [HugePedia]
snp3D : Map Gene to Disease8794
BioCentury BCIQTNFRSF10C
ClinGenTNFRSF10C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8794
Chemical/Pharm GKB GenePA36599
Clinical trialTNFRSF10C
Miscellaneous
canSAR (ICR)TNFRSF10C (select the gene name)
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTNFRSF10C
EVEXTNFRSF10C
GoPubMedTNFRSF10C
iHOPTNFRSF10C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:59:56 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.