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TNFRSF10D (TNF receptor superfamily member 10d)

Identity

Alias (NCBI)CD264
DCR2
TRAIL-R4
TRAILR4
TRUNDD
HGNC (Hugo) TNFRSF10D
HGNC Alias symbDcR2
TRUNDD
TRAILR4
CD264
HGNC Previous nametumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
LocusID (NCBI) 8793
Atlas_Id 42608
Location 8p21.3  [Link to chromosome band 8p21]
Location_base_pair Starts at 23135591 and ends at 23164027 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TNFRSF10D   11907
Cards
Entrez_Gene (NCBI)TNFRSF10D    TNF receptor superfamily member 10d
AliasesCD264; DCR2; TRAIL-R4; TRAILR4; 
TRUNDD
GeneCards (Weizmann)TNFRSF10D
Ensembl hg19 (Hinxton)ENSG00000173530 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173530 [Gene_View]  ENSG00000173530 [Sequence]  chr8:23135591-23164027 [Contig_View]  TNFRSF10D [Vega]
ICGC DataPortalENSG00000173530
TCGA cBioPortalTNFRSF10D
AceView (NCBI)TNFRSF10D
Genatlas (Paris)TNFRSF10D
SOURCE (Princeton)TNFRSF10D
Genetics Home Reference (NIH)TNFRSF10D
Genomic and cartography
GoldenPath hg38 (UCSC)TNFRSF10D  -     chr8:23135591-23164027 -  8p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TNFRSF10D  -     8p21.3   [Description]    (hg19-Feb_2009)
GoldenPathTNFRSF10D - 8p21.3 [CytoView hg19]  TNFRSF10D - 8p21.3 [CytoView hg38]
ImmunoBaseENSG00000173530
Genome Data Viewer NCBITNFRSF10D [Mapview hg19]  
OMIM603614   
Gene and transcription
Genbank (Entrez)AA743393 AF021232 AF021233 AF023849 AF029761
RefSeq transcript (Entrez)NM_003840
Consensus coding sequences : CCDS (NCBI)TNFRSF10D
Gene ExpressionTNFRSF10D [ NCBI-GEO ]   TNFRSF10D [ EBI - ARRAY_EXPRESS ]   TNFRSF10D [ SEEK ]   TNFRSF10D [ MEM ]
Gene Expression Viewer (FireBrowse)TNFRSF10D [ Firebrowse - Broad ]
GenevisibleExpression of TNFRSF10D in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8793
GTEX Portal (Tissue expression)TNFRSF10D
Human Protein AtlasENSG00000173530-TNFRSF10D [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBN6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UBN6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBN6
PhosPhoSitePlusQ9UBN6
Domaine pattern : Prosite (Expaxy)TNFR_NGFR_1 (PS00652)    TNFR_NGFR_2 (PS50050)   
Domains : Interpro (EBI)TNFR/NGFR_Cys_rich_reg    TNFR_10    TNFRSF10_N   
Domain families : Pfam (Sanger)TNFR_c6 (PF00020)   
Domain families : Pfam (NCBI)pfam00020   
Domain families : Smart (EMBL)TNFR (SM00208)  
Conserved Domain (NCBI)TNFRSF10D
SuperfamilyQ9UBN6
AlphaFold pdb e-kbQ9UBN6   
Human Protein Atlas [tissue]ENSG00000173530-TNFRSF10D [tissue]
HPRD04682
Protein Interaction databases
DIP (DOE-UCLA)Q9UBN6
IntAct (EBI)Q9UBN6
BioGRIDTNFRSF10D
STRING (EMBL)TNFRSF10D
ZODIACTNFRSF10D
Ontologies - Pathways
QuickGOQ9UBN6
Ontology : AmiGOtransmembrane signaling receptor activity  protein binding  plasma membrane  plasma membrane  apoptotic process  signal transduction  cell surface receptor signaling pathway  cell surface  integral component of membrane  regulation of apoptotic process  negative regulation of apoptotic process  TRAIL binding  leukocyte migration  
Ontology : EGO-EBItransmembrane signaling receptor activity  protein binding  plasma membrane  plasma membrane  apoptotic process  signal transduction  cell surface receptor signaling pathway  cell surface  integral component of membrane  regulation of apoptotic process  negative regulation of apoptotic process  TRAIL binding  leukocyte migration  
Pathways : KEGGCytokine-cytokine receptor interaction    Apoptosis    Natural killer cell mediated cytotoxicity    Measles    Influenza A   
NDEx NetworkTNFRSF10D
Atlas of Cancer Signalling NetworkTNFRSF10D
Wikipedia pathwaysTNFRSF10D
Orthology - Evolution
OrthoDB8793
GeneTree (enSembl)ENSG00000173530
Phylogenetic Trees/Animal Genes : TreeFamTNFRSF10D
Homologs : HomoloGeneTNFRSF10D
Homology/Alignments : Family Browser (UCSC)TNFRSF10D
Gene fusions - Rearrangements
Fusion : QuiverTNFRSF10D
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNFRSF10D [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNFRSF10D
dbVarTNFRSF10D
ClinVarTNFRSF10D
MonarchTNFRSF10D
1000_GenomesTNFRSF10D 
Exome Variant ServerTNFRSF10D
GNOMAD BrowserENSG00000173530
Varsome BrowserTNFRSF10D
ACMGTNFRSF10D variants
VarityQ9UBN6
Genomic Variants (DGV)TNFRSF10D [DGVbeta]
DECIPHERTNFRSF10D [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTNFRSF10D 
Mutations
ICGC Data PortalTNFRSF10D 
TCGA Data PortalTNFRSF10D 
Broad Tumor PortalTNFRSF10D
OASIS PortalTNFRSF10D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNFRSF10D  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTNFRSF10D
Mutations and Diseases : HGMDTNFRSF10D
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTNFRSF10D
DgiDB (Drug Gene Interaction Database)TNFRSF10D
DoCM (Curated mutations)TNFRSF10D
CIViC (Clinical Interpretations of Variants in Cancer)TNFRSF10D
Cancer3DTNFRSF10D
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603614   
Orphanet
DisGeNETTNFRSF10D
MedgenTNFRSF10D
Genetic Testing Registry TNFRSF10D
NextProtQ9UBN6 [Medical]
GENETestsTNFRSF10D
Target ValidationTNFRSF10D
Huge Navigator TNFRSF10D [HugePedia]
ClinGenTNFRSF10D
Clinical trials, drugs, therapy
MyCancerGenomeTNFRSF10D
Protein Interactions : CTDTNFRSF10D
Pharm GKB GenePA36600
PharosQ9UBN6
Clinical trialTNFRSF10D
Miscellaneous
canSAR (ICR)TNFRSF10D
HarmonizomeTNFRSF10D
DataMed IndexTNFRSF10D
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTNFRSF10D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:35:42 CEST 2021

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