Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TNFRSF18 (tumor necrosis factor receptor superfamily member 18)

Identity

Alias_namestumor necrosis factor receptor superfamily
Alias_symbol (synonym)AITR
GITR
CD357
Other aliasGITR-D
HGNC (Hugo) TNFRSF18
LocusID (NCBI) 8784
Atlas_Id 42617
Location 1p36.33  [Link to chromosome band 1p36]
Location_base_pair Starts at 1138888 and ends at 1142089 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TNFRSF18   11914
Cards
Entrez_Gene (NCBI)TNFRSF18  8784  tumor necrosis factor receptor superfamily member 18
AliasesAITR; CD357; GITR; GITR-D
GeneCards (Weizmann)TNFRSF18
Ensembl hg19 (Hinxton)ENSG00000186891 [Gene_View]  chr1:1138888-1142089 [Contig_View]  TNFRSF18 [Vega]
Ensembl hg38 (Hinxton)ENSG00000186891 [Gene_View]  chr1:1138888-1142089 [Contig_View]  TNFRSF18 [Vega]
ICGC DataPortalENSG00000186891
TCGA cBioPortalTNFRSF18
AceView (NCBI)TNFRSF18
Genatlas (Paris)TNFRSF18
WikiGenes8784
SOURCE (Princeton)TNFRSF18
Genetics Home Reference (NIH)TNFRSF18
Genomic and cartography
GoldenPath hg19 (UCSC)TNFRSF18  -     chr1:1138888-1142089 -  1p36.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TNFRSF18  -     1p36.33   [Description]    (hg38-Dec_2013)
EnsemblTNFRSF18 - 1p36.33 [CytoView hg19]  TNFRSF18 - 1p36.33 [CytoView hg38]
Mapping of homologs : NCBITNFRSF18 [Mapview hg19]  TNFRSF18 [Mapview hg38]
OMIM603905   
Gene and transcription
Genbank (Entrez)AF117297 AF125304 AF241229 AY358877 BC152381
RefSeq transcript (Entrez)NM_004195 NM_148901 NM_148902
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929288
Consensus coding sequences : CCDS (NCBI)TNFRSF18
Cluster EST : UnigeneHs.212680 [ NCBI ]
CGAP (NCI)Hs.212680
Alternative Splicing GalleryENSG00000186891
Gene ExpressionTNFRSF18 [ NCBI-GEO ]   TNFRSF18 [ EBI - ARRAY_EXPRESS ]   TNFRSF18 [ SEEK ]   TNFRSF18 [ MEM ]
Gene Expression Viewer (FireBrowse)TNFRSF18 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8784
GTEX Portal (Tissue expression)TNFRSF18
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5U5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5U5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5U5
Splice isoforms : SwissVarQ9Y5U5
PhosPhoSitePlusQ9Y5U5
Domains : Interpro (EBI)TNFR/NGFR_Cys_rich_reg    TNFR_18   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)TNFR (SM00208)  
Conserved Domain (NCBI)TNFRSF18
DMDM Disease mutations8784
Blocks (Seattle)TNFRSF18
SuperfamilyQ9Y5U5
Human Protein AtlasENSG00000186891
Peptide AtlasQ9Y5U5
HPRD04879
IPIIPI00217555   IPI00375404   IPI00001796   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5U5
IntAct (EBI)Q9Y5U5
FunCoupENSG00000186891
BioGRIDTNFRSF18
STRING (EMBL)TNFRSF18
ZODIACTNFRSF18
Ontologies - Pathways
QuickGOQ9Y5U5
Ontology : AmiGOpositive regulation of leukocyte migration  tumor necrosis factor-activated receptor activity  extracellular region  plasma membrane  integral component of plasma membrane  inflammatory response  immune response  signal transduction  multicellular organism development  extrinsic apoptotic signaling pathway via death domain receptors  external side of plasma membrane  response to lipopolysaccharide  tumor necrosis factor-mediated signaling pathway  regulation of cell proliferation  positive regulation of tyrosine phosphorylation of Stat1 protein  negative regulation of apoptotic process  positive regulation of cell adhesion  
Ontology : EGO-EBIpositive regulation of leukocyte migration  tumor necrosis factor-activated receptor activity  extracellular region  plasma membrane  integral component of plasma membrane  inflammatory response  immune response  signal transduction  multicellular organism development  extrinsic apoptotic signaling pathway via death domain receptors  external side of plasma membrane  response to lipopolysaccharide  tumor necrosis factor-mediated signaling pathway  regulation of cell proliferation  positive regulation of tyrosine phosphorylation of Stat1 protein  negative regulation of apoptotic process  positive regulation of cell adhesion  
Pathways : KEGGCytokine-cytokine receptor interaction   
NDEx NetworkTNFRSF18
Atlas of Cancer Signalling NetworkTNFRSF18
Wikipedia pathwaysTNFRSF18
Orthology - Evolution
OrthoDB8784
GeneTree (enSembl)ENSG00000186891
Phylogenetic Trees/Animal Genes : TreeFamTNFRSF18
HOVERGENQ9Y5U5
HOGENOMQ9Y5U5
Homologs : HomoloGeneTNFRSF18
Homology/Alignments : Family Browser (UCSC)TNFRSF18
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNFRSF18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNFRSF18
dbVarTNFRSF18
ClinVarTNFRSF18
1000_GenomesTNFRSF18 
Exome Variant ServerTNFRSF18
ExAC (Exome Aggregation Consortium)TNFRSF18 (select the gene name)
Genetic variants : HAPMAP8784
Genomic Variants (DGV)TNFRSF18 [DGVbeta]
DECIPHER (Syndromes)1:1138888-1142089  ENSG00000186891
CONAN: Copy Number AnalysisTNFRSF18 
Mutations
ICGC Data PortalTNFRSF18 
TCGA Data PortalTNFRSF18 
Broad Tumor PortalTNFRSF18
OASIS PortalTNFRSF18 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNFRSF18  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTNFRSF18
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TNFRSF18
DgiDB (Drug Gene Interaction Database)TNFRSF18
DoCM (Curated mutations)TNFRSF18 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TNFRSF18 (select a term)
intoGenTNFRSF18
Cancer3DTNFRSF18(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603905   
Orphanet
MedgenTNFRSF18
Genetic Testing Registry TNFRSF18
NextProtQ9Y5U5 [Medical]
TSGene8784
GENETestsTNFRSF18
Huge Navigator TNFRSF18 [HugePedia]
snp3D : Map Gene to Disease8784
BioCentury BCIQTNFRSF18
ClinGenTNFRSF18
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8784
Chemical/Pharm GKB GenePA36607
Clinical trialTNFRSF18
Miscellaneous
canSAR (ICR)TNFRSF18 (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTNFRSF18
EVEXTNFRSF18
GoPubMedTNFRSF18
iHOPTNFRSF18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:22:55 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.