TNFSF11 (tumor necrosis factor (ligand) superfamily, member 11)

Identity

Other names	CD254
	ODF
	OPGL
	OPTB2
	RANKL
	TRANCE
	hRANKL2
	sOdf
HGNC	TNFSF11
Location	13q14
Location_base_pair	Starts at 42046298 and ends at 42080148 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TNFSF11   11926
Entrez_Gene	TNFSF11  8600  tumor necrosis factor (ligand) superfamily, member 11
	Cards
GeneCards	TNFSF11
Ensembl	ENSG00000120659 [Gene_View]  TNFSF11 [Vega]
Genatlas	TNFSF11
	Genomic and cartography
GoldenPath	TNFSF11  -  13q14   chr13:42046298-42080148 +  13q14.11   [Description]    (hg18-March_2006)
Ensembl	TNFSF11 - 13q14.11 [CytoView]
NCBI	Mapview
OMIM	259710 Disease map [OMIM]
OMIM	602642 Disease map [OMIM]
HomoloGene	TNFSF11
	Gene and transcription
Genbank	AA504211 [ ENTREZ ]
Genbank	AB037599 [ ENTREZ ]
Genbank	AB061227 [ ENTREZ ]
Genbank	AB064268 [ ENTREZ ]
Genbank	AB064269 [ ENTREZ ]
RefSeq	NM_003701 [ SRS ]    NM_003701 [ ENTREZ ]
RefSeq	NM_033012 [ SRS ]    NM_033012 [ ENTREZ ]
RefSeq	AC_000056 [ SRS ]    AC_000056 [ ENTREZ ]
RefSeq	AC_000145 [ SRS ]    AC_000145 [ ENTREZ ]
RefSeq	NC_000013 [ SRS ]    NC_000013 [ ENTREZ ]
RefSeq	NT_024524 [ SRS ]    NT_024524 [ ENTREZ ]
RefSeq	NW_001838073 [ SRS ]    NW_001838073 [ ENTREZ ]
RefSeq	NW_925473 [ SRS ]    NW_925473 [ ENTREZ ]
CCDS	TNFSF11 CCDS - NCBI
AceView	TNFSF11 AceView - NCBI
Unigene	Hs.333791 [ SRS ]    Hs.333791 [ NCBI ]
Fast-db	18033 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O14788 [ SRS]    O14788 [ EXPASY ]     O14788 [ INTERPRO ]     O14788 [ UNIPROT ] O14788 [ VarSplice FASTA ]
Prosite	PS00251 TNF_1 [ SRS ]    PS00251 TNF_1 [ Expasy ]
Prosite	PS50049 TNF_2 [ SRS ]    PS50049 TNF_2 [ Expasy ]
Interpro	IPR017355 TNF10_TNF11 [ SRS ]    IPR017355 TNF10_TNF11 [ EBI ]
Interpro	IPR006052 TNF_family [ SRS ]    IPR006052 TNF_family [ EBI ]
Interpro	IPR008983 Tumour_necrosis_fac-like [ SRS ]    IPR008983 Tumour_necrosis_fac-like [ EBI ]
CluSTr	O14788
Pfam	PF00229 TNF [ SRS ]    PF00229 TNF [ Sanger ]    pfam00229 [ NCBI-CDD ]
Smart	SM00207 TNF [EMBL]
Prodom	PD002012 TNF_subf[INRA-Toulouse]
Prodom	O14788 TNF11_HUMAN [ Domain structure ]   O14788 TNF11_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	O14788
HPRD	04031
	Protein Interaction databases
DIP	O14788
IntAct	O14788
	Polymorphism : SNP, mutations, diseases
OMIM	259710    [ map ]
OMIM	602642    [ map ]
GENETests	259710
GENETests	602642
SNP	TNFSF11 [dbSNP-NCBI]
SNP	NM_003701 [SNP-NCI]
SNP	NM_033012 [SNP-NCI]
SNP	TNFSF11 [GeneSNPs - Utah]  TNFSF11] [HGBASE - SRS]
HAPMAP	TNFSF11 [HAPMAP]
HGMD	TNFSF11
Genetic Association	TNFSF11
CDC HuGE	TNFSF11
	General knowledge
Family Browser	TNFSF11 [UCSC Family Browser]
SOURCE	NM_003701
SOURCE	NM_033012
SMD	Hs.333791
SAGE	Hs.333791
GO	receptor activity [Amigo]  receptor activity
GO	cytokine activity [Amigo]  cytokine activity
GO	tumor necrosis factor receptor binding [Amigo]  tumor necrosis factor receptor binding
GO	extracellular region [Amigo]  extracellular region
GO	extracellular space [Amigo]  extracellular space
GO	cytoplasm [Amigo]  cytoplasm
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	immune response [Amigo]  immune response
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	cell differentiation [Amigo]  cell differentiation
GO	positive regulation of osteoclast differentiation [Amigo]  positive regulation of osteoclast differentiation
GO	positive regulation of bone resorption [Amigo]  positive regulation of bone resorption
BIOCARTA	Bone Remodelling    [Genes]
KEGG	Cytokine-cytokine receptor interaction
PubGene	TNFSF11
TreeFam	TNFSF11
CTD	8600 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TNFSF11 Related clones (RZPD - Berlin)
	PubMed
PubMed	135 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:16:24 2008