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TNRC6A (trinucleotide repeat containing 6A)

Identity

Alias_namesTNRC6
trinucleotide repeat containing 6
Alias_symbol (synonym)CAGH26
KIAA1460
GW182
Other aliasGW1
HGNC (Hugo) TNRC6A
LocusID (NCBI) 27327
Atlas_Id 50817
Location 16p12.1  [Link to chromosome band 16p12]
Location_base_pair Starts at 24729728 and ends at 24826226 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RNF112 (17p11.2) / TNRC6A (16p12.1)SETX (9q34.13) / TNRC6A (16p12.1)SLC9A9 (3q24) / TNRC6A (16p12.1)
SMG6 (17p13.3) / TNRC6A (16p12.1)SORBS2 (4q35.1) / TNRC6A (16p12.1)STRN4 (19q13.32) / TNRC6A (16p12.1)
TG (8q24.22) / TNRC6A (16p12.1)TNRC6A (16p12.1) / PRKCB (16p12.2)TNRC6A (16p12.1) / RPA1 (17p13.3)
TNRC6A (16p12.1) / TNRC6A (16p12.1)WDFY4 (10q11.22) / TNRC6A (16p12.1)ZNF814 (19q13.43) / TNRC6A (16p12.1)
TNRC6A 16p12.1 / PRKCB 16p12.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TNRC6A   11969
Cards
Entrez_Gene (NCBI)TNRC6A  27327  trinucleotide repeat containing 6A
AliasesCAGH26; GW1; GW182; TNRC6
GeneCards (Weizmann)TNRC6A
Ensembl hg19 (Hinxton)ENSG00000090905 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000090905 [Gene_View]  chr16:24729728-24826226 [Contig_View]  TNRC6A [Vega]
ICGC DataPortalENSG00000090905
TCGA cBioPortalTNRC6A
AceView (NCBI)TNRC6A
Genatlas (Paris)TNRC6A
WikiGenes27327
SOURCE (Princeton)TNRC6A
Genetics Home Reference (NIH)TNRC6A
Genomic and cartography
GoldenPath hg38 (UCSC)TNRC6A  -     chr16:24729728-24826226 +  16p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TNRC6A  -     16p12.1   [Description]    (hg19-Feb_2009)
EnsemblTNRC6A - 16p12.1 [CytoView hg19]  TNRC6A - 16p12.1 [CytoView hg38]
Mapping of homologs : NCBITNRC6A [Mapview hg19]  TNRC6A [Mapview hg38]
OMIM610739   
Gene and transcription
Genbank (Entrez)AB040893 AJ492221 AK001773 AK025277 AK025696
RefSeq transcript (Entrez)NM_001330520 NM_014494
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TNRC6A
Cluster EST : UnigeneHs.655057 [ NCBI ]
CGAP (NCI)Hs.655057
Alternative Splicing GalleryENSG00000090905
Gene ExpressionTNRC6A [ NCBI-GEO ]   TNRC6A [ EBI - ARRAY_EXPRESS ]   TNRC6A [ SEEK ]   TNRC6A [ MEM ]
Gene Expression Viewer (FireBrowse)TNRC6A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27327
GTEX Portal (Tissue expression)TNRC6A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NDV7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NDV7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NDV7
Splice isoforms : SwissVarQ8NDV7
PhosPhoSitePlusQ8NDV7
Domains : Interpro (EBI)Argonaute_hook_dom    GW182_M_dom    Nucleotide-bd_a/b_plait    RRM_dom    TNRC6_PABC-bd    TNRC6A   
Domain families : Pfam (Sanger)Ago_hook (PF10427)    M_domain (PF12938)    TNRC6-PABC_bdg (PF16608)   
Domain families : Pfam (NCBI)pfam10427    pfam12938    pfam16608   
Conserved Domain (NCBI)TNRC6A
DMDM Disease mutations27327
Blocks (Seattle)TNRC6A
SuperfamilyQ8NDV7
Human Protein AtlasENSG00000090905
Peptide AtlasQ8NDV7
HPRD11640
IPIIPI00395878   IPI00160265   IPI00382618   IPI00554606   IPI00554721   IPI00853634   IPI00479354   IPI00908679   
Protein Interaction databases
DIP (DOE-UCLA)Q8NDV7
IntAct (EBI)Q8NDV7
FunCoupENSG00000090905
BioGRIDTNRC6A
STRING (EMBL)TNRC6A
ZODIACTNRC6A
Ontologies - Pathways
QuickGOQ8NDV7
Ontology : AmiGOP-body  RNA binding  protein binding  nucleoplasm  nucleoplasm  Golgi apparatus  cytosol  Wnt signaling pathway, calcium modulating pathway  gene silencing by RNA  micro-ribonucleoprotein complex  posttranscriptional gene silencing by RNA  gene silencing by miRNA  miRNA mediated inhibition of translation  intracellular membrane-bounded organelle  phosphatidylinositol-mediated signaling  
Ontology : EGO-EBIP-body  RNA binding  protein binding  nucleoplasm  nucleoplasm  Golgi apparatus  cytosol  Wnt signaling pathway, calcium modulating pathway  gene silencing by RNA  micro-ribonucleoprotein complex  posttranscriptional gene silencing by RNA  gene silencing by miRNA  miRNA mediated inhibition of translation  intracellular membrane-bounded organelle  phosphatidylinositol-mediated signaling  
NDEx NetworkTNRC6A
Atlas of Cancer Signalling NetworkTNRC6A
Wikipedia pathwaysTNRC6A
Orthology - Evolution
OrthoDB27327
GeneTree (enSembl)ENSG00000090905
Phylogenetic Trees/Animal Genes : TreeFamTNRC6A
HOVERGENQ8NDV7
HOGENOMQ8NDV7
Homologs : HomoloGeneTNRC6A
Homology/Alignments : Family Browser (UCSC)TNRC6A
Gene fusions - Rearrangements
Fusion : MitelmanTNRC6A/PRKCB [16p12.1/16p12.2]  
Fusion: TCGATNRC6A 16p12.1 PRKCB 16p12.2 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNRC6A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNRC6A
dbVarTNRC6A
ClinVarTNRC6A
1000_GenomesTNRC6A 
Exome Variant ServerTNRC6A
ExAC (Exome Aggregation Consortium)TNRC6A (select the gene name)
Genetic variants : HAPMAP27327
Genomic Variants (DGV)TNRC6A [DGVbeta]
DECIPHERTNRC6A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTNRC6A 
Mutations
ICGC Data PortalTNRC6A 
TCGA Data PortalTNRC6A 
Broad Tumor PortalTNRC6A
OASIS PortalTNRC6A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNRC6A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTNRC6A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TNRC6A
DgiDB (Drug Gene Interaction Database)TNRC6A
DoCM (Curated mutations)TNRC6A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TNRC6A (select a term)
intoGenTNRC6A
Cancer3DTNRC6A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610739   
Orphanet
MedgenTNRC6A
Genetic Testing Registry TNRC6A
NextProtQ8NDV7 [Medical]
TSGene27327
GENETestsTNRC6A
Target ValidationTNRC6A
Huge Navigator TNRC6A [HugePedia]
snp3D : Map Gene to Disease27327
BioCentury BCIQTNRC6A
ClinGenTNRC6A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27327
Chemical/Pharm GKB GenePA36656
Clinical trialTNRC6A
Miscellaneous
canSAR (ICR)TNRC6A (select the gene name)
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTNRC6A
EVEXTNRC6A
GoPubMedTNRC6A
iHOPTNRC6A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:00:12 CEST 2017

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