Atlas of Genetics and Cytogenetics in Oncology and Haematology

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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

Donate (in Euros)

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TPM2 (tropomyosin 2 (beta))


Other namesAMCD1
HGNC (Hugo) TPM2
LocusID (NCBI) 7169
Location 9p13.3
Location_base_pair Starts at 35681990 and ends at 35690053 bp from pter ( according to hg19-Feb_2009)

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

HGNC (Hugo)TPM2   12011
Entrez_Gene (NCBI)TPM2  7169  tropomyosin 2 (beta)
GeneCards (Weizmann)TPM2
Ensembl hg19 (Hinxton)ENSG00000198467 [Gene_View]  chr9:35681990-35690053 [Contig_View]  TPM2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000198467 [Gene_View]  chr9:35681990-35690053 [Contig_View]  TPM2 [Vega]
ICGC DataPortalENSG00000198467
AceView (NCBI)TPM2
Genatlas (Paris)TPM2
SOURCE (Princeton)TPM2
Genomic and cartography
GoldenPath hg19 (UCSC)TPM2  -     chr9:35681990-35690053 -  9p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TPM2  -     9p13.3   [Description]    (hg38-Dec_2013)
EnsemblTPM2 - 9p13.3 [CytoView hg19]  TPM2 - 9p13.3 [CytoView hg38]
Mapping of homologs : NCBITPM2 [Mapview hg19]  TPM2 [Mapview hg38]
OMIM108120   190990   255310   601680   609285   
Gene and transcription
Genbank (Entrez)AA394062 AI360640 AI660199 AJ572605 AK130045
RefSeq transcript (Entrez)NM_001145822 NM_001301226 NM_001301227 NM_003289 NM_213674
RefSeq genomic (Entrez)NC_000009 NC_018920 NG_011620 NT_008413 NW_004929342
Consensus coding sequences : CCDS (NCBI)TPM2
Cluster EST : UnigeneHs.300772 [ NCBI ]
CGAP (NCI)Hs.300772
Alternative Splicing : Fast-db (Paris)GSHG0030790
Alternative Splicing GalleryENSG00000198467
Gene ExpressionTPM2 [ NCBI-GEO ]     TPM2 [ SEEK ]   TPM2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07951 (Uniprot)
NextProtP07951  [Medical]
With graphics : InterProP07951
Splice isoforms : SwissVarP07951 (Swissvar)
Domaine pattern : Prosite (Expaxy)TROPOMYOSIN (PS00326)   
Domains : Interpro (EBI)Tropomyosin   
Related proteins : CluSTrP07951
Domain families : Pfam (Sanger)Tropomyosin (PF00261)   
Domain families : Pfam (NCBI)pfam00261   
DMDM Disease mutations7169
Blocks (Seattle)P07951
Human Protein AtlasENSG00000198467
Peptide AtlasP07951
IPIIPI00013991   IPI00220709   IPI00218820   IPI00910712   IPI00513698   IPI00646748   
Protein Interaction databases
IntAct (EBI)P07951
Ontologies - Pathways
Ontology : AmiGOactin binding  cytosol  muscle thin filament tropomyosin  muscle contraction  structural constituent of muscle  muscle filament sliding  regulation of ATPase activity  
Ontology : EGO-EBIactin binding  cytosol  muscle thin filament tropomyosin  muscle contraction  structural constituent of muscle  muscle filament sliding  regulation of ATPase activity  
Pathways : KEGGCardiac muscle contraction    Adrenergic signaling in cardiomyocytes    Hypertrophic cardiomyopathy (HCM)    Dilated cardiomyopathy   
Protein Interaction DatabaseTPM2
DoCM (Curated mutations)TPM2
Wikipedia pathwaysTPM2
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerTPM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TPM2
Exome Variant ServerTPM2
SNP (GeneSNP Utah)TPM2
Genetic variants : HAPMAPTPM2
Genomic Variants (DGV)TPM2 [DGVbeta]
ICGC Data PortalENSG00000198467 
Somatic Mutations in Cancer : COSMICTPM2 
CONAN: Copy Number AnalysisTPM2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)Leiden Muscular Dystrophy pages
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
DECIPHER (Syndromes)9:35681990-35690053
Mutations and Diseases : HGMDTPM2
OMIM108120    190990    255310    601680    609285   
NextProtP07951 [Medical]
Disease Genetic AssociationTPM2
Huge Navigator TPM2 [HugePedia]  TPM2 [HugeCancerGEM]
snp3D : Map Gene to Disease7169
DGIdb (Drug Gene Interaction db)TPM2
General knowledge
Homologs : HomoloGeneTPM2
Homology/Alignments : Family Browser (UCSC)TPM2
Phylogenetic Trees/Animal Genes : TreeFamTPM2
Chemical/Protein Interactions : CTD7169
Chemical/Pharm GKB GenePA36691
Clinical trialTPM2
Cancer Resource (Charite)ENSG00000198467
Other databases
PubMed80 Pubmed reference(s) in Entrez
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI


Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 17:41:47 CET 2015

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