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TPM2 (tropomyosin 2 (beta))

Identity

Other namesAMCD1
DA1
DA2B
HEL-S-273
NEM4
TMSB
HGNC (Hugo) TPM2
LocusID (NCBI) 7169
Location 9p13.3
Location_base_pair Starts at 35682923 and ends at 35690053 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TPM2   12011
Cards
Entrez_Gene (NCBI)TPM2  7169  tropomyosin 2 (beta)
GeneCards (Weizmann)TPM2
Ensembl (Hinxton)ENSG00000198467 [Gene_View]  chr9:35682923-35690053 [Contig_View]  TPM2 [Vega]
ICGC DataPortalENSG00000198467
cBioPortalTPM2
AceView (NCBI)TPM2
Genatlas (Paris)TPM2
WikiGenes7169
SOURCE (Princeton)NM_001145822 NM_003289 NM_213674
Genomic and cartography
GoldenPath (UCSC)TPM2  -  9p13.3   chr9:35682923-35690053 -  9p13.3   [Description]    (hg19-Feb_2009)
EnsemblTPM2 - 9p13.3 [CytoView]
Mapping of homologs : NCBITPM2 [Mapview]
OMIM108120   190990   255310   601680   609285   
Gene and transcription
Genbank (Entrez)AA394062 AI360640 AI660199 AJ572605 AK130045
RefSeq transcript (Entrez)NM_001145822 NM_003289 NM_213674
RefSeq genomic (Entrez)AC_000141 NC_000009 NC_018920 NG_011620 NT_008413 NW_001839149 NW_004929342
Consensus coding sequences : CCDS (NCBI)TPM2
Cluster EST : UnigeneHs.300772 [ NCBI ]
CGAP (NCI)Hs.300772
Alternative Splicing : Fast-db (Paris)GSHG0030790
Alternative Splicing GalleryENSG00000198467
Gene ExpressionTPM2 [ NCBI-GEO ]     TPM2 [ SEEK ]   TPM2 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07951 (Uniprot)
NextProtP07951  [Medical]
With graphics : InterProP07951
Splice isoforms : SwissVarP07951 (Swissvar)
Domaine pattern : Prosite (Expaxy)TROPOMYOSIN (PS00326)   
Domains : Interpro (EBI)Tropomyosin [organisation]  
Related proteins : CluSTrP07951
Domain families : Pfam (Sanger)Tropomyosin (PF00261)   
Domain families : Pfam (NCBI)pfam00261   
DMDM Disease mutations7169
Blocks (Seattle)P07951
Human Protein AtlasENSG00000198467 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP07951
HPRD11768
IPIIPI00013991   IPI00220709   IPI00218820   IPI00910712   IPI00513698   IPI00646748   
Protein Interaction databases
DIP (DOE-UCLA)P07951
IntAct (EBI)P07951
FunCoupENSG00000198467
BioGRIDTPM2
InParanoidP07951
Interologous Interaction database P07951
IntegromeDBTPM2
STRING (EMBL)TPM2
Ontologies - Pathways
Ontology : AmiGOactin binding  cytosol  muscle thin filament tropomyosin  muscle contraction  structural constituent of muscle  muscle filament sliding  regulation of ATPase activity  
Ontology : EGO-EBIactin binding  cytosol  muscle thin filament tropomyosin  muscle contraction  structural constituent of muscle  muscle filament sliding  regulation of ATPase activity  
Pathways : KEGGCardiac muscle contraction    Adrenergic signaling in cardiomyocytes    Hypertrophic cardiomyopathy (HCM)    Dilated cardiomyopathy   
Protein Interaction DatabaseTPM2
Wikipedia pathwaysTPM2
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TPM2
snp3D : Map Gene to Disease7169
SNP (GeneSNP Utah)TPM2
SNP : HGBaseTPM2
Genetic variants : HAPMAPTPM2
Exome VariantTPM2
1000_GenomesTPM2 
ICGC programENSG00000198467 
Somatic Mutations in Cancer : COSMICTPM2 
CONAN: Copy Number AnalysisTPM2 
Mutations and Diseases : HGMDTPM2
Mutations and Diseases : intOGenTPM2
Genomic VariantsTPM2  TPM2 [DGVbeta]
dbVarTPM2
ClinVarTPM2
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM108120    190990    255310    601680    609285   
MedgenTPM2
GENETestsTPM2
Disease Genetic AssociationTPM2
Huge Navigator TPM2 [HugePedia]  TPM2 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneTPM2
Homology/Alignments : Family Browser (UCSC)TPM2
Phylogenetic Trees/Animal Genes : TreeFamTPM2
Chemical/Protein Interactions : CTD7169
Chemical/Pharm GKB GenePA36691
Clinical trialTPM2
Cancer Resource (Charite)ENSG00000198467
Other databases
Probes
Litterature
PubMed77 Pubmed reference(s) in Entrez
CoreMineTPM2
iHOPTPM2
OncoSearchTPM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 17:08:26 CEST 2014

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