TTR (transthyretin)

Identity

Other names	HsT2651
	PALB
	TBPA
HGNC	TTR
Location	18q12.1
Location_base_pair	Starts at 27425838 and ends at 27432794 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TTR   12405
Entrez_Gene	TTR  7276  transthyretin
	Cards
GeneCards	TTR
Ensembl	ENSG00000118271 [Gene_View]  TTR [Vega]
Genatlas	TTR
	Genomic and cartography
GoldenPath	TTR  -  18q12.1   chr18:27425838-27432794 +  18q12.1   [Description]    (hg18-March_2006)
Ensembl	TTR - 18q12.1 [CytoView]
NCBI	Mapview
OMIM	176300 Disease map [OMIM]
HomoloGene	TTR
	Gene and transcription
Genbank	AF162690 [ ENTREZ ]
Genbank	AK312051 [ ENTREZ ]
Genbank	BC005310 [ ENTREZ ]
Genbank	BC020791 [ ENTREZ ]
Genbank	BT007189 [ ENTREZ ]
RefSeq	NM_000371 [ SRS ]    NM_000371 [ ENTREZ ]
RefSeq	AC_000061 [ SRS ]    AC_000061 [ ENTREZ ]
RefSeq	AC_000150 [ SRS ]    AC_000150 [ ENTREZ ]
RefSeq	NC_000018 [ SRS ]    NC_000018 [ ENTREZ ]
RefSeq	NT_010966 [ SRS ]    NT_010966 [ ENTREZ ]
RefSeq	NW_001838467 [ SRS ]    NW_001838467 [ ENTREZ ]
RefSeq	NW_927095 [ SRS ]    NW_927095 [ ENTREZ ]
CCDS	TTR CCDS - NCBI
AceView	TTR AceView - NCBI
Unigene	Hs.427202 [ SRS ]    Hs.427202 [ NCBI ]
Fast-db	3089 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P02766 [ SRS]    P02766 [ EXPASY ]     P02766 [ INTERPRO ]     P02766 [ UNIPROT ] P02766 [ VarSplice FASTA ]
Prosite	PS00768 TRANSTHYRETIN_1 [ SRS ]    PS00768 TRANSTHYRETIN_1 [ Expasy ]
Prosite	PS00769 TRANSTHYRETIN_2 [ SRS ]    PS00769 TRANSTHYRETIN_2 [ Expasy ]
Interpro	IPR000895 Transthyretin [ SRS ]    IPR000895 Transthyretin [ EBI ]
CluSTr	P02766
Pfam	PF00576 Transthyretin [ SRS ]    PF00576 Transthyretin [ Sanger ]    pfam00576 [ NCBI-CDD ]
Smart	SM00095 TR_THY [EMBL]
Prodom	PD003457 Transthyretin[INRA-Toulouse]
Prodom	P02766 TTHY_HUMAN [ Domain structure ]   P02766 TTHY_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P02766
PDB	1BM7 [ SRS ]    1BM7 [ PdbSum ],   1BM7 [ IMB ]   1BM7 [ RSDB ]
PDB	1BMZ [ SRS ]    1BMZ [ PdbSum ],   1BMZ [ IMB ]   1BMZ [ RSDB ]
PDB	1BZ8 [ SRS ]    1BZ8 [ PdbSum ],   1BZ8 [ IMB ]   1BZ8 [ RSDB ]
PDB	1BZD [ SRS ]    1BZD [ PdbSum ],   1BZD [ IMB ]   1BZD [ RSDB ]
PDB	1BZE [ SRS ]    1BZE [ PdbSum ],   1BZE [ IMB ]   1BZE [ RSDB ]
PDB	1DVQ [ SRS ]    1DVQ [ PdbSum ],   1DVQ [ IMB ]   1DVQ [ RSDB ]
PDB	1DVS [ SRS ]    1DVS [ PdbSum ],   1DVS [ IMB ]   1DVS [ RSDB ]
PDB	1DVT [ SRS ]    1DVT [ PdbSum ],   1DVT [ IMB ]   1DVT [ RSDB ]
PDB	1DVU [ SRS ]    1DVU [ PdbSum ],   1DVU [ IMB ]   1DVU [ RSDB ]
PDB	1DVX [ SRS ]    1DVX [ PdbSum ],   1DVX [ IMB ]   1DVX [ RSDB ]
PDB	1DVY [ SRS ]    1DVY [ PdbSum ],   1DVY [ IMB ]   1DVY [ RSDB ]
PDB	1DVZ [ SRS ]    1DVZ [ PdbSum ],   1DVZ [ IMB ]   1DVZ [ RSDB ]
PDB	1E3F [ SRS ]    1E3F [ PdbSum ],   1E3F [ IMB ]   1E3F [ RSDB ]
PDB	1E4H [ SRS ]    1E4H [ PdbSum ],   1E4H [ IMB ]   1E4H [ RSDB ]
PDB	1E5A [ SRS ]    1E5A [ PdbSum ],   1E5A [ IMB ]   1E5A [ RSDB ]
PDB	1ETA [ SRS ]    1ETA [ PdbSum ],   1ETA [ IMB ]   1ETA [ RSDB ]
PDB	1ETB [ SRS ]    1ETB [ PdbSum ],   1ETB [ IMB ]   1ETB [ RSDB ]
PDB	1F41 [ SRS ]    1F41 [ PdbSum ],   1F41 [ IMB ]   1F41 [ RSDB ]
PDB	1F64 [ SRS ]    1F64 [ PdbSum ],   1F64 [ IMB ]   1F64 [ RSDB ]
PDB	1F86 [ SRS ]    1F86 [ PdbSum ],   1F86 [ IMB ]   1F86 [ RSDB ]
PDB	1FH2 [ SRS ]    1FH2 [ PdbSum ],   1FH2 [ IMB ]   1FH2 [ RSDB ]
PDB	1FHN [ SRS ]    1FHN [ PdbSum ],   1FHN [ IMB ]   1FHN [ RSDB ]
PDB	1G1O [ SRS ]    1G1O [ PdbSum ],   1G1O [ IMB ]   1G1O [ RSDB ]
PDB	1GKO [ SRS ]    1GKO [ PdbSum ],   1GKO [ IMB ]   1GKO [ RSDB ]
PDB	1ICT [ SRS ]    1ICT [ PdbSum ],   1ICT [ IMB ]   1ICT [ RSDB ]
PDB	1III [ SRS ]    1III [ PdbSum ],   1III [ IMB ]   1III [ RSDB ]
PDB	1IIK [ SRS ]    1IIK [ PdbSum ],   1IIK [ IMB ]   1IIK [ RSDB ]
PDB	1IJN [ SRS ]    1IJN [ PdbSum ],   1IJN [ IMB ]   1IJN [ RSDB ]
PDB	1QAB [ SRS ]    1QAB [ PdbSum ],   1QAB [ IMB ]   1QAB [ RSDB ]
PDB	1QWH [ SRS ]    1QWH [ PdbSum ],   1QWH [ IMB ]   1QWH [ RSDB ]
PDB	1RLB [ SRS ]    1RLB [ PdbSum ],   1RLB [ IMB ]   1RLB [ RSDB ]
PDB	1SOK [ SRS ]    1SOK [ PdbSum ],   1SOK [ IMB ]   1SOK [ RSDB ]
PDB	1SOQ [ SRS ]    1SOQ [ PdbSum ],   1SOQ [ IMB ]   1SOQ [ RSDB ]
PDB	1THA [ SRS ]    1THA [ PdbSum ],   1THA [ IMB ]   1THA [ RSDB ]
PDB	1THC [ SRS ]    1THC [ PdbSum ],   1THC [ IMB ]   1THC [ RSDB ]
PDB	1TLM [ SRS ]    1TLM [ PdbSum ],   1TLM [ IMB ]   1TLM [ RSDB ]
PDB	1TSH [ SRS ]    1TSH [ PdbSum ],   1TSH [ IMB ]   1TSH [ RSDB ]
PDB	1TT6 [ SRS ]    1TT6 [ PdbSum ],   1TT6 [ IMB ]   1TT6 [ RSDB ]
PDB	1TTA [ SRS ]    1TTA [ PdbSum ],   1TTA [ IMB ]   1TTA [ RSDB ]
PDB	1TTB [ SRS ]    1TTB [ PdbSum ],   1TTB [ IMB ]   1TTB [ RSDB ]
PDB	1TTC [ SRS ]    1TTC [ PdbSum ],   1TTC [ IMB ]   1TTC [ RSDB ]
PDB	1TTR [ SRS ]    1TTR [ PdbSum ],   1TTR [ IMB ]   1TTR [ RSDB ]
PDB	1TYR [ SRS ]    1TYR [ PdbSum ],   1TYR [ IMB ]   1TYR [ RSDB ]
PDB	1TZ8 [ SRS ]    1TZ8 [ PdbSum ],   1TZ8 [ IMB ]   1TZ8 [ RSDB ]
PDB	1U21 [ SRS ]    1U21 [ PdbSum ],   1U21 [ IMB ]   1U21 [ RSDB ]
PDB	1X7S [ SRS ]    1X7S [ PdbSum ],   1X7S [ IMB ]   1X7S [ RSDB ]
PDB	1X7T [ SRS ]    1X7T [ PdbSum ],   1X7T [ IMB ]   1X7T [ RSDB ]
PDB	1Y1D [ SRS ]    1Y1D [ PdbSum ],   1Y1D [ IMB ]   1Y1D [ RSDB ]
PDB	1Z7J [ SRS ]    1Z7J [ PdbSum ],   1Z7J [ IMB ]   1Z7J [ RSDB ]
PDB	1ZCR [ SRS ]    1ZCR [ PdbSum ],   1ZCR [ IMB ]   1ZCR [ RSDB ]
PDB	1ZD6 [ SRS ]    1ZD6 [ PdbSum ],   1ZD6 [ IMB ]   1ZD6 [ RSDB ]
PDB	2B14 [ SRS ]    2B14 [ PdbSum ],   2B14 [ IMB ]   2B14 [ RSDB ]
PDB	2B15 [ SRS ]    2B15 [ PdbSum ],   2B15 [ IMB ]   2B15 [ RSDB ]
PDB	2B16 [ SRS ]    2B16 [ PdbSum ],   2B16 [ IMB ]   2B16 [ RSDB ]
PDB	2B77 [ SRS ]    2B77 [ PdbSum ],   2B77 [ IMB ]   2B77 [ RSDB ]
PDB	2B9A [ SRS ]    2B9A [ PdbSum ],   2B9A [ IMB ]   2B9A [ RSDB ]
PDB	2F7I [ SRS ]    2F7I [ PdbSum ],   2F7I [ IMB ]   2F7I [ RSDB ]
PDB	2F8I [ SRS ]    2F8I [ PdbSum ],   2F8I [ IMB ]   2F8I [ RSDB ]
PDB	2FBR [ SRS ]    2FBR [ PdbSum ],   2FBR [ IMB ]   2FBR [ RSDB ]
PDB	2FLM [ SRS ]    2FLM [ PdbSum ],   2FLM [ IMB ]   2FLM [ RSDB ]
PDB	2G3X [ SRS ]    2G3X [ PdbSum ],   2G3X [ IMB ]   2G3X [ RSDB ]
PDB	2G3Z [ SRS ]    2G3Z [ PdbSum ],   2G3Z [ IMB ]   2G3Z [ RSDB ]
PDB	2G4E [ SRS ]    2G4E [ PdbSum ],   2G4E [ IMB ]   2G4E [ RSDB ]
PDB	2G4G [ SRS ]    2G4G [ PdbSum ],   2G4G [ IMB ]   2G4G [ RSDB ]
PDB	2G5U [ SRS ]    2G5U [ PdbSum ],   2G5U [ IMB ]   2G5U [ RSDB ]
PDB	2G9K [ SRS ]    2G9K [ PdbSum ],   2G9K [ IMB ]   2G9K [ RSDB ]
PDB	2GAB [ SRS ]    2GAB [ PdbSum ],   2GAB [ IMB ]   2GAB [ RSDB ]
PDB	2H4E [ SRS ]    2H4E [ PdbSum ],   2H4E [ IMB ]   2H4E [ RSDB ]
PDB	2NOY [ SRS ]    2NOY [ PdbSum ],   2NOY [ IMB ]   2NOY [ RSDB ]
PDB	2PAB [ SRS ]    2PAB [ PdbSum ],   2PAB [ IMB ]   2PAB [ RSDB ]
PDB	2QEL [ SRS ]    2QEL [ PdbSum ],   2QEL [ IMB ]   2QEL [ RSDB ]
PDB	2QGB [ SRS ]    2QGB [ PdbSum ],   2QGB [ IMB ]   2QGB [ RSDB ]
PDB	2QGC [ SRS ]    2QGC [ PdbSum ],   2QGC [ IMB ]   2QGC [ RSDB ]
PDB	2QGD [ SRS ]    2QGD [ PdbSum ],   2QGD [ IMB ]   2QGD [ RSDB ]
PDB	2QGE [ SRS ]    2QGE [ PdbSum ],   2QGE [ IMB ]   2QGE [ RSDB ]
PDB	2ROX [ SRS ]    2ROX [ PdbSum ],   2ROX [ IMB ]   2ROX [ RSDB ]
PDB	2ROY [ SRS ]    2ROY [ PdbSum ],   2ROY [ IMB ]   2ROY [ RSDB ]
PDB	2TRH [ SRS ]    2TRH [ PdbSum ],   2TRH [ IMB ]   2TRH [ RSDB ]
PDB	2TRY [ SRS ]    2TRY [ PdbSum ],   2TRY [ IMB ]   2TRY [ RSDB ]
PDB	3B56 [ SRS ]    3B56 [ PdbSum ],   3B56 [ IMB ]   3B56 [ RSDB ]
PDB	5TTR [ SRS ]    5TTR [ PdbSum ],   5TTR [ IMB ]   5TTR [ RSDB ]
HPRD	01447
	Protein Interaction databases
DIP	P02766
IntAct	P02766
	Polymorphism : SNP, mutations, diseases
OMIM	176300    [ map ]
GENETests	176300
SNP	TTR [dbSNP-NCBI]
SNP	NM_000371 [SNP-NCI]
SNP	TTR [GeneSNPs - Utah]  TTR] [HGBASE - SRS]
HAPMAP	TTR [HAPMAP]
HGMD	TTR
Genetic Association	TTR
CDC HuGE	TTR
	General knowledge
Family Browser	TTR [UCSC Family Browser]
SOURCE	NM_000371
SMD	Hs.427202
SAGE	Hs.427202
GO	hormone activity [Amigo]  hormone activity
GO	steroid binding [Amigo]  steroid binding
GO	extracellular region [Amigo]  extracellular region
GO	extracellular space [Amigo]  extracellular space
GO	thyroid hormone generation [Amigo]  thyroid hormone generation
GO	transport [Amigo]  transport
GO	thyroid hormone transmembrane transporter activity [Amigo]  thyroid hormone transmembrane transporter activity
GO	retinal binding [Amigo]  retinal binding
GO	retinol binding [Amigo]  retinol binding
GO	hormone binding [Amigo]  hormone binding
PubGene	TTR
TreeFam	TTR
CTD	7276 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TTR Related clones (RZPD - Berlin)
	PubMed
PubMed	228 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:17:42 2008