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TTYH2 (tweety family member 2)

Identity

Alias_namestweety (Drosophila) homolog 2
tweety homolog 2 (Drosophila)
Alias_symbol (synonym)C17orf29
Other alias
HGNC (Hugo) TTYH2
LocusID (NCBI) 94015
Atlas_Id 42954
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 72209696 and ends at 72258157 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
HELZ (17q24.2) / TTYH2 (17q25.1)MOG (6p22.1) / TTYH2 (17q25.1)RASSF3 (12q14.2) / TTYH2 (17q25.1)
RPL38 (17q25.1) / TTYH2 (17q25.1)TEX2 (17q23.3) / TTYH2 (17q25.1)TMEM94 (17q25.1) / TTYH2 (17q25.1)
TTYH2 (17q25.1) / DCAF5 (14q24.1)HELZ 17q24.2 / TTYH2 17q25.1KIAA0195 17q25.1 / TTYH2 17q25.1
TEX2 17q23.3 / TTYH2 17q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Adenocarcinoma


External links

Nomenclature
HGNC (Hugo)TTYH2   13877
Cards
Entrez_Gene (NCBI)TTYH2  94015  tweety family member 2
AliasesC17orf29
GeneCards (Weizmann)TTYH2
Ensembl hg19 (Hinxton)ENSG00000141540 [Gene_View]  chr17:72209696-72258157 [Contig_View]  TTYH2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000141540 [Gene_View]  chr17:72209696-72258157 [Contig_View]  TTYH2 [Vega]
ICGC DataPortalENSG00000141540
TCGA cBioPortalTTYH2
AceView (NCBI)TTYH2
Genatlas (Paris)TTYH2
WikiGenes94015
SOURCE (Princeton)TTYH2
Genetics Home Reference (NIH)TTYH2
Genomic and cartography
GoldenPath hg19 (UCSC)TTYH2  -     chr17:72209696-72258157 +  17q25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TTYH2  -     17q25.1   [Description]    (hg38-Dec_2013)
EnsemblTTYH2 - 17q25.1 [CytoView hg19]  TTYH2 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBITTYH2 [Mapview hg19]  TTYH2 [Mapview hg38]
OMIM608855   
Gene and transcription
Genbank (Entrez)AF319952 AK058197 AK091085 AK126955 AK296511
RefSeq transcript (Entrez)NM_032646 NM_052869
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)TTYH2
Cluster EST : UnigeneHs.27935 [ NCBI ]
CGAP (NCI)Hs.27935
Alternative Splicing GalleryENSG00000141540
Gene ExpressionTTYH2 [ NCBI-GEO ]   TTYH2 [ EBI - ARRAY_EXPRESS ]   TTYH2 [ SEEK ]   TTYH2 [ MEM ]
Gene Expression Viewer (FireBrowse)TTYH2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)94015
GTEX Portal (Tissue expression)TTYH2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BSA4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BSA4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BSA4
Splice isoforms : SwissVarQ9BSA4
PhosPhoSitePlusQ9BSA4
Domains : Interpro (EBI)Tweety   
Domain families : Pfam (Sanger)Tweety (PF04906)   
Domain families : Pfam (NCBI)pfam04906   
Conserved Domain (NCBI)TTYH2
DMDM Disease mutations94015
Blocks (Seattle)TTYH2
SuperfamilyQ9BSA4
Human Protein AtlasENSG00000141540
Peptide AtlasQ9BSA4
HPRD16394
IPIIPI00305281   IPI00470343   IPI00975559   
Protein Interaction databases
DIP (DOE-UCLA)Q9BSA4
IntAct (EBI)Q9BSA4
FunCoupENSG00000141540
BioGRIDTTYH2
STRING (EMBL)TTYH2
ZODIACTTYH2
Ontologies - Pathways
QuickGOQ9BSA4
Ontology : AmiGOchloride channel activity  protein binding  plasma membrane  chloride channel complex  chloride transmembrane transport  
Ontology : EGO-EBIchloride channel activity  protein binding  plasma membrane  chloride channel complex  chloride transmembrane transport  
NDEx NetworkTTYH2
Atlas of Cancer Signalling NetworkTTYH2
Wikipedia pathwaysTTYH2
Orthology - Evolution
OrthoDB94015
GeneTree (enSembl)ENSG00000141540
Phylogenetic Trees/Animal Genes : TreeFamTTYH2
HOVERGENQ9BSA4
HOGENOMQ9BSA4
Homologs : HomoloGeneTTYH2
Homology/Alignments : Family Browser (UCSC)TTYH2
Gene fusions - Rearrangements
Fusion : MitelmanHELZ/TTYH2 [17q24.2/17q25.1]  [t(17;17)(q24;q25)]  
Fusion : MitelmanKIAA0195/TTYH2 [17q25.1/17q25.1]  [t(17;17)(q25;q25)]  
Fusion : MitelmanRASSF3/TTYH2 [12q14.2/17q25.1]  [t(12;17)(q14;q25)]  
Fusion : MitelmanTEX2/TTYH2 [17q23.3/17q25.1]  [t(17;17)(q23;q25)]  
Fusion: TCGAHELZ 17q24.2 TTYH2 17q25.1 BRCA
Fusion: TCGAKIAA0195 17q25.1 TTYH2 17q25.1 OV
Fusion: TCGATEX2 17q23.3 TTYH2 17q25.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTTYH2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTYH2
dbVarTTYH2
ClinVarTTYH2
1000_GenomesTTYH2 
Exome Variant ServerTTYH2
ExAC (Exome Aggregation Consortium)TTYH2 (select the gene name)
Genetic variants : HAPMAP94015
Genomic Variants (DGV)TTYH2 [DGVbeta]
DECIPHER (Syndromes)17:72209696-72258157  ENSG00000141540
CONAN: Copy Number AnalysisTTYH2 
Mutations
ICGC Data PortalTTYH2 
TCGA Data PortalTTYH2 
Broad Tumor PortalTTYH2
OASIS PortalTTYH2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTTYH2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTTYH2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TTYH2
DgiDB (Drug Gene Interaction Database)TTYH2
DoCM (Curated mutations)TTYH2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TTYH2 (select a term)
intoGenTTYH2
Cancer3DTTYH2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608855   
Orphanet
MedgenTTYH2
Genetic Testing Registry TTYH2
NextProtQ9BSA4 [Medical]
TSGene94015
GENETestsTTYH2
Huge Navigator TTYH2 [HugePedia]
snp3D : Map Gene to Disease94015
BioCentury BCIQTTYH2
ClinGenTTYH2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD94015
Chemical/Pharm GKB GenePA37823
Clinical trialTTYH2
Miscellaneous
canSAR (ICR)TTYH2 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTTYH2
EVEXTTYH2
GoPubMedTTYH2
iHOPTTYH2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:23:49 CEST 2017

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