UBA3 (ubiquitin-like modifier activating enzyme 3)

Identity

Other names	DKFZp566J164
	MGC22384
	UBE1C
	hUBA3
Hugo	UBE1C
Location	3p24.3-p13
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
Hugo	UBE1C
GDB	UBA3
Entrez_Gene	UBA3  9039  ubiquitin-like modifier activating enzyme 3
	Cards
GeneCards	UBA3
Ensembl	UBA3 [Search_View]   ENSG00000144744 [Gene_View]
Genatlas	UBA3
GeneLynx	UBA3
eGenome	UBA3
euGene	9039
	Genomic and cartography
GoldenPath	UBA3  -     chr3:69186572-69212214 -  3p14.1   [Description]    (hg18-March_2006)
Ensembl	UBA3 - 3p14.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	UBA3
	Gene and transcription
Genbank	AB012190 [ ENTREZ ]
Genbank	AF046024 [ ENTREZ ]
Genbank	AK002159 [ ENTREZ ]
Genbank	AK289392 [ ENTREZ ]
Genbank	AL117566 [ ENTREZ ]
RefSeq	NM_003968 [ SRS ]    NM_003968 [ ENTREZ ]
RefSeq	NM_198195 [ SRS ]    NM_198195 [ ENTREZ ]
RefSeq	NM_198197 [ SRS ]    NM_198197 [ ENTREZ ]
RefSeq	AC_000046 [ SRS ]    AC_000046 [ ENTREZ ]
RefSeq	NC_000003 [ SRS ]    NC_000003 [ ENTREZ ]
RefSeq	NT_022459 [ SRS ]    NT_022459 [ ENTREZ ]
RefSeq	NW_921651 [ SRS ]    NW_921651 [ ENTREZ ]
AceView	UBA3 AceView - NCBI
Unigene	Hs.154320 [ SRS ]    Hs.154320 [ NCBI ]     HS154320 [ spliceNest ]
Fast-db	9593 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q8TBC4 [ SRS]    Q8TBC4 [ EXPASY ]     Q8TBC4 [ INTERPRO ]
Prosite	PS00536 UBIQUITIN_ACTIVAT_1 [ SRS ]    PS00536 UBIQUITIN_ACTIVAT_1 [ Expasy ]
Prosite	PS00865 UBIQUITIN_ACTIVAT_2 [ SRS ]    PS00865 UBIQUITIN_ACTIVAT_2 [ Expasy ]
Interpro	IPR014929 E2_bd [ SRS ]    IPR014929 E2_bd [ EBI ]
Interpro	IPR000594 ThiF_NAD_FAD_bd [ SRS ]    IPR000594 ThiF_NAD_FAD_bd [ EBI ]
Interpro	IPR000127 UBact_repeat [ SRS ]    IPR000127 UBact_repeat [ EBI ]
Interpro	IPR000011 UBQ-activ_enz_E1 [ SRS ]    IPR000011 UBQ-activ_enz_E1 [ EBI ]
CluSTr	Q8TBC4
Pfam	PF08825 E2_bind [ SRS ]    PF08825 E2_bind [ Sanger ]    pfam08825 [ NCBI-CDD ]
Pfam	PF00899 ThiF [ SRS ]    PF00899 ThiF [ Sanger ]    pfam00899 [ NCBI-CDD ]
Pfam	PF02134 UBACT [ SRS ]    PF02134 UBACT [ Sanger ]    pfam02134 [ NCBI-CDD ]
Blocks	Q8TBC4
PDB	1R4M [ SRS ]    1R4M [ PdbSum ],   1R4M [ IMB ]   1R4M [ RSDB ]
PDB	1R4N [ SRS ]    1R4N [ PdbSum ],   1R4N [ IMB ]   1R4N [ RSDB ]
PDB	1TT5 [ SRS ]    1TT5 [ PdbSum ],   1TT5 [ IMB ]   1TT5 [ RSDB ]
PDB	1Y8X [ SRS ]    1Y8X [ PdbSum ],   1Y8X [ IMB ]   1Y8X [ RSDB ]
PDB	1YOV [ SRS ]    1YOV [ PdbSum ],   1YOV [ IMB ]   1YOV [ RSDB ]
PDB	2NVU [ SRS ]    2NVU [ PdbSum ],   2NVU [ IMB ]   2NVU [ RSDB ]
HPRD	04413
	Protein Interaction databases
DIP	Q8TBC4
IntAct	Q8TBC4
	Polymorphism : SNP, mutations, diseases
OMIM	603172    [ map ]
GENECLINICS	603172
SNP	UBA3 [dbSNP-NCBI]
SNP	NM_003968 [SNP-NCI]
SNP	NM_198195 [SNP-NCI]
SNP	NM_198197 [SNP-NCI]
SNP	UBA3 [GeneSNPs - Utah]  UBA3] [HGBASE - SRS]
HAPMAP	UBA3 [HAPMAP]
HGMD	UBE1C
	General knowledge
Family Browser	UBA3 [UCSC Family Browser]
SOURCE	NM_003968
SOURCE	NM_198195
SOURCE	NM_198197
SMD	Hs.154320
SAGE	Hs.154320
Enzyme	6.3.2.- [ Enzyme-SRS ]   6.3.2.- [ Brenda-SRS ]   6.3.2.- [ KEGG ]   6.3.2.- [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	cellular_component [Amigo]  cellular_component
GO	nucleus [Amigo]  nucleus
GO	protein modification process [Amigo]  protein modification process
GO	proteolysis [Amigo]  proteolysis
GO	ubiquitin cycle [Amigo]  ubiquitin cycle
GO	cell cycle [Amigo]  cell cycle
GO	metabolic process [Amigo]  metabolic process
GO	small protein activating enzyme activity [Amigo]  small protein activating enzyme activity
GO	ligase activity [Amigo]  ligase activity
GO	protein heterodimerization activity [Amigo]  protein heterodimerization activity
PubGene	UBA3
TreeFam	UBE1C
CTD	9039 [Comparative Genomics Database]
	Other databases
	Probes
Probe	UBE1C Related clones (RZPD - Berlin)
	PubMed
PubMed	21 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:33:59 2008