Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

UBE2I (ubiquitin-conjugating enzyme E2I)

Identity

Other namesC358B7.1
P18
UBC9
HGNC (Hugo) UBE2I
LocusID (NCBI) 7329
Location 16p13.3
Location_base_pair Starts at 1359628 and ends at 1377019 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)UBE2I   12485
Entrez_Gene (NCBI)UBE2I  7329  ubiquitin-conjugating enzyme E2I
Cards
GeneCards (Weizmann)UBE2I
Ensembl (Hinxton)ENSG00000103275 [Gene_View]  chr16:1359628-1377019 [Contig_View]  UBE2I [Vega]
AceView (NCBI)UBE2I
Genatlas (Paris)UBE2I
SOURCE (Stanford)NM_003345 NM_194259 NM_194260 NM_194261
Genomic and cartography
GoldenPath (UCSC)UBE2I  -  16p13.3   chr16:1359628-1377019 +  16p13.3   [Description]    (hg19-Feb_2009)
EnsemblUBE2I - 16p13.3 [CytoView]
Mapping of homologs : NCBIUBE2I [Mapview]
OMIM601661   
Gene and transcription
Genbank (Entrez)AB208988 AJ002385 AK024172 AK093616 AK291118
RefSeq transcript (SRS)NM_003345 NM_194259 NM_194260 NM_194261
RefSeq transcript (Entrez)NM_003345 NM_194259 NM_194260 NM_194261
RefSeq genomic (SRS)AC_000148 NC_000016 NC_018927 NT_010393 NW_001838339 NW_004078085
RefSeq genomic (Entrez)AC_000148 NC_000016 NC_018927 NT_010393 NW_001838339 NW_004078085
Consensus coding sequences : CCDS (NCBI)UBE2I
Cluster EST : UnigeneHs.302903 [ SRS ] Hs.302903 [ NCBI ]
CGAP (NCI)Hs.302903
Alternative Splicing : Fast-db (Paris)GSHG0010832
Alternative Splicing GalleryENSG00000103275
Gene ExpressionUBE2I [ NCBI-GEO ]   UBE2I [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP63279 (SRS) P63279 (Uniprot)
NextProtP63279
With graphics : InterProP63279
Splice isoforms : SwissVarP63279(Swissvar)
Domaine pattern : Prosite (SRS)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (SRS)Ubc9    UBQ-conjugat_E2    UBQ-conjugating_AS    UBQ-conjugating_enzyme/RWD   
Domains : Interpro (EBI)Ubc9    UBQ-conjugat_E2    UBQ-conjugating_AS    UBQ-conjugating_enzyme/RWD   
Related proteins : CluSTrP63279
Domain families : Pfam (SRS)UQ_con (PF00179)   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
DMDM7329
Blocks (Seattle)P63279
PDB (SRS)1A3S    1KPS    1Z5Q    1Z5S    2GRN    2GRO    2GRP    2GRQ    2GRR    2O25    2PE6    2PX9    2XWU    3A4S    3UIN    3UIO    3UIP   
PDB (PDBSum)1A3S    1KPS    1Z5Q    1Z5S    2GRN    2GRO    2GRP    2GRQ    2GRR    2O25    2PE6    2PX9    2XWU    3A4S    3UIN    3UIO    3UIP   
PDB (IMB)1A3S    1KPS    1Z5Q    1Z5S    2GRN    2GRO    2GRP    2GRQ    2GRR    2O25    2PE6    2PX9    2XWU    3A4S    3UIN    3UIO    3UIP   
PDB (RSDB)1A3S    1KPS    1Z5Q    1Z5S    2GRN    2GRO    2GRP    2GRQ    2GRR    2O25    2PE6    2PX9    2XWU    3A4S    3UIN    3UIO    3UIP   
Human Protein AtlasENSG00000103275
HPRD09045
IPIIPI00032957   IPI00975499   IPI00450472   
Protein Interaction databases
DIP (DOE-UCLA)P63279
IntAct (EBI)P63279
FunCoupENSG00000103275
REACTOMEUBE2I
Protein Interaction Database7329
BioGRIDUBE2I
InParanoidP63279
Interologous Interaction database P63279
IntegromeDBUBE2I
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)UBE2I
SNP (GeneSNP Utah)UBE2I
SNP : HGBaseUBE2I
Genetic variants : HAPMAPUBE2I
Somatic Mutations in Cancer : COSMICUBE2I 
CONAN: Copy Number AnalysisUBE2I 
Mutations and Diseases : HGMDUBE2I
OMIM601661   
GENETests601661   
Disease Genetic AssociationUBE2I
Huge Navigator UBE2I [HugePedia]  UBE2I [HugeCancerGEM]
Genomic VariantsUBE2I  UBE2I [DGVbeta]
ClinVarUBE2I
snp3D : Map Gene to Disease7329
General knowledge
Homologs : HomoloGeneUBE2I
Homology/Alignments : Family Browser (UCSC)UBE2I
Phylogenetic Trees/Animal Genes : TreeFamUBE2I
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.- [ Enzyme-SRS ]   6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
Chemical/Protein Interactions : CTD7329
Chemical/Pharm GKB GenePA37134
Clinical trialUBE2I
Cancer Resource (Charite)ENSG00000103275
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  synaptonemal complex  fibrillar center  ubiquitin-protein ligase activity  protein binding  ATP binding  nucleus  cytoplasm  cellular protein modification process  ubiquitin-dependent protein catabolic process  chromosome segregation  mitosis  protein C-terminus binding  transcription factor binding  regulation of receptor activity  PML body  protein sumoylation  protein sumoylation  virus-host interaction  SUMO ligase activity  enzyme binding  dendrite  positive regulation of intracellular steroid hormone receptor signaling pathway  proteasomal ubiquitin-dependent protein catabolic process  HLH domain binding  bHLH transcription factor binding  synapse  negative regulation of transcription, DNA-dependent  positive regulation of sequence-specific DNA binding transcription factor activity  cell division  RING-like zinc finger domain binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  synaptonemal complex  fibrillar center  ubiquitin-protein ligase activity  protein binding  ATP binding  nucleus  cytoplasm  cellular protein modification process  ubiquitin-dependent protein catabolic process  chromosome segregation  mitosis  protein C-terminus binding  transcription factor binding  regulation of receptor activity  PML body  protein sumoylation  protein sumoylation  virus-host interaction  SUMO ligase activity  enzyme binding  dendrite  positive regulation of intracellular steroid hormone receptor signaling pathway  proteasomal ubiquitin-dependent protein catabolic process  HLH domain binding  bHLH transcription factor binding  synapse  negative regulation of transcription, DNA-dependent  positive regulation of sequence-specific DNA binding transcription factor activity  cell division  RING-like zinc finger domain binding  
Pathways : BIOCARTABasic Mechanisms of SUMOylation [Genes]    SUMOylation as a mechanism to modulate CtBP-dependent gene responses [Genes]    ER¿associated degradation (ERAD) Pathway [Genes]   
Other databases
Probes
Litterature
PubMed292 Pubmed reference(s) in Entrez
PubGeneUBE2I
iHOPUBE2I
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:30:09 CEST 2013
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.