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UBE2S (ubiquitin conjugating enzyme E2 S)

Identity

Alias_namesubiquitin-conjugating enzyme E2S
Alias_symbol (synonym)E2-EPF
Other aliasE2EPF
EPF5
HGNC (Hugo) UBE2S
LocusID (NCBI) 27338
Atlas_Id 42753
Location 19q13.42  [Link to chromosome band 19q13]
Location_base_pair Starts at 55401282 and ends at 55407957 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
UBE2S (19q13.42) / IDI2-AS1 (10p15.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBE2S   17895
Cards
Entrez_Gene (NCBI)UBE2S  27338  ubiquitin conjugating enzyme E2 S
AliasesE2-EPF; E2EPF; EPF5
GeneCards (Weizmann)UBE2S
Ensembl hg19 (Hinxton)ENSG00000108106 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108106 [Gene_View]  chr19:55401282-55407957 [Contig_View]  UBE2S [Vega]
ICGC DataPortalENSG00000108106
TCGA cBioPortalUBE2S
AceView (NCBI)UBE2S
Genatlas (Paris)UBE2S
WikiGenes27338
SOURCE (Princeton)UBE2S
Genetics Home Reference (NIH)UBE2S
Genomic and cartography
GoldenPath hg38 (UCSC)UBE2S  -     chr19:55401282-55407957 -  19q13.42   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBE2S  -     19q13.42   [Description]    (hg19-Feb_2009)
EnsemblUBE2S - 19q13.42 [CytoView hg19]  UBE2S - 19q13.42 [CytoView hg38]
Mapping of homologs : NCBIUBE2S [Mapview hg19]  UBE2S [Mapview hg38]
OMIM610309   
Gene and transcription
Genbank (Entrez)AB062397 BC004236 BC007554 BC065364 BC066948
RefSeq transcript (Entrez)NM_014501
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBE2S
Cluster EST : UnigeneHs.396393 [ NCBI ]
CGAP (NCI)Hs.396393
Alternative Splicing GalleryENSG00000108106
Gene ExpressionUBE2S [ NCBI-GEO ]   UBE2S [ EBI - ARRAY_EXPRESS ]   UBE2S [ SEEK ]   UBE2S [ MEM ]
Gene Expression Viewer (FireBrowse)UBE2S [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27338
GTEX Portal (Tissue expression)UBE2S
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16763   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16763  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16763
Splice isoforms : SwissVarQ16763
PhosPhoSitePlusQ16763
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_AS    UBQ-conjugating_enzyme/RWD   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
Conserved Domain (NCBI)UBE2S
DMDM Disease mutations27338
Blocks (Seattle)UBE2S
PDB (SRS)1ZDN    5BNB    5L9T   
PDB (PDBSum)1ZDN    5BNB    5L9T   
PDB (IMB)1ZDN    5BNB    5L9T   
PDB (RSDB)1ZDN    5BNB    5L9T   
Structural Biology KnowledgeBase1ZDN    5BNB    5L9T   
SCOP (Structural Classification of Proteins)1ZDN    5BNB    5L9T   
CATH (Classification of proteins structures)1ZDN    5BNB    5L9T   
SuperfamilyQ16763
Human Protein AtlasENSG00000108106
Peptide AtlasQ16763
HPRD15603
IPIIPI00217949   IPI00744698   
Protein Interaction databases
DIP (DOE-UCLA)Q16763
IntAct (EBI)Q16763
FunCoupENSG00000108106
BioGRIDUBE2S
STRING (EMBL)UBE2S
ZODIACUBE2S
Ontologies - Pathways
QuickGOQ16763
Ontology : AmiGOubiquitin-protein transferase activity  ubiquitin-protein transferase activity  ATP binding  nucleoplasm  anaphase-promoting complex  cytoplasm  cytosol  cellular protein modification process  exit from mitosis  exit from mitosis  free ubiquitin chain polymerization  protein ubiquitination  anaphase-promoting complex-dependent catabolic process  ubiquitin protein ligase binding  protein K29-linked ubiquitination  protein K27-linked ubiquitination  cell division  ubiquitin protein ligase activity  ubiquitin conjugating enzyme activity  protein K63-linked ubiquitination  protein K11-linked ubiquitination  protein K6-linked ubiquitination  positive regulation of ubiquitin protein ligase activity  
Ontology : EGO-EBIubiquitin-protein transferase activity  ubiquitin-protein transferase activity  ATP binding  nucleoplasm  anaphase-promoting complex  cytoplasm  cytosol  cellular protein modification process  exit from mitosis  exit from mitosis  free ubiquitin chain polymerization  protein ubiquitination  anaphase-promoting complex-dependent catabolic process  ubiquitin protein ligase binding  protein K29-linked ubiquitination  protein K27-linked ubiquitination  cell division  ubiquitin protein ligase activity  ubiquitin conjugating enzyme activity  protein K63-linked ubiquitination  protein K11-linked ubiquitination  protein K6-linked ubiquitination  positive regulation of ubiquitin protein ligase activity  
Pathways : KEGGUbiquitin mediated proteolysis   
NDEx NetworkUBE2S
Atlas of Cancer Signalling NetworkUBE2S
Wikipedia pathwaysUBE2S
Orthology - Evolution
OrthoDB27338
GeneTree (enSembl)ENSG00000108106
Phylogenetic Trees/Animal Genes : TreeFamUBE2S
HOVERGENQ16763
HOGENOMQ16763
Homologs : HomoloGeneUBE2S
Homology/Alignments : Family Browser (UCSC)UBE2S
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBE2S [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBE2S
dbVarUBE2S
ClinVarUBE2S
1000_GenomesUBE2S 
Exome Variant ServerUBE2S
ExAC (Exome Aggregation Consortium)UBE2S (select the gene name)
Genetic variants : HAPMAP27338
Genomic Variants (DGV)UBE2S [DGVbeta]
DECIPHERUBE2S [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBE2S 
Mutations
ICGC Data PortalUBE2S 
TCGA Data PortalUBE2S 
Broad Tumor PortalUBE2S
OASIS PortalUBE2S [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBE2S  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBE2S
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBE2S
DgiDB (Drug Gene Interaction Database)UBE2S
DoCM (Curated mutations)UBE2S (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBE2S (select a term)
intoGenUBE2S
Cancer3DUBE2S(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610309   
Orphanet
MedgenUBE2S
Genetic Testing Registry UBE2S
NextProtQ16763 [Medical]
TSGene27338
GENETestsUBE2S
Target ValidationUBE2S
Huge Navigator UBE2S [HugePedia]
snp3D : Map Gene to Disease27338
BioCentury BCIQUBE2S
ClinGenUBE2S
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27338
Chemical/Pharm GKB GenePA134904441
Clinical trialUBE2S
Miscellaneous
canSAR (ICR)UBE2S (select the gene name)
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBE2S
EVEXUBE2S
GoPubMedUBE2S
iHOPUBE2S
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:37:09 CEST 2017

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