Identity
HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
E2-EPF,E2EPF,EPF5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27338
MIM: 610309
HGNC: 17895
Ensembl: ENSG00000108106
Variants:
dbSNP: 27338
ClinVar: 27338
TCGA: ENSG00000108106
COSMIC: UBE2S
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000108106 | ENST00000264552 | Q16763 |
| ENSG00000108106 | ENST00000587845 | K7EPJ1 |
| ENSG00000108106 | ENST00000589978 | K7EM75 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38597436 | 2024 | [High expression of UBE2S promotes progression of hepatocellular carcinoma by increasing cancer cell stemness]. | 0 |
| 38597436 | 2024 | [High expression of UBE2S promotes progression of hepatocellular carcinoma by increasing cancer cell stemness]. | 0 |
| 37422473 | 2023 | UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer. | 8 |
| 37791471 | 2023 | As a potential predictor of pan-cancer, UBE2S is related to tumor-associated macrophage infiltration. | 0 |
| 37422473 | 2023 | UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer. | 8 |
| 37791471 | 2023 | As a potential predictor of pan-cancer, UBE2S is related to tumor-associated macrophage infiltration. | 0 |
| 34942047 | 2022 | Functional conservation and divergence of the helix-turn-helix motif of E2 ubiquitin-conjugating enzymes. | 9 |
| 35637955 | 2022 | UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer. | 13 |
| 35658829 | 2022 | UBE2S promotes the development of ovarian cancer by promoting PI3K/AKT/mTOR signaling pathway to regulate cell cycle and apoptosis. | 12 |
| 35863455 | 2022 | Knockout of UBE2S inhibits the proliferation of gastric cancer cells and induces apoptosis by FAS-mediated death receptor pathway. | 2 |
| 34942047 | 2022 | Functional conservation and divergence of the helix-turn-helix motif of E2 ubiquitin-conjugating enzymes. | 9 |
| 35637955 | 2022 | UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer. | 13 |
| 35658829 | 2022 | UBE2S promotes the development of ovarian cancer by promoting PI3K/AKT/mTOR signaling pathway to regulate cell cycle and apoptosis. | 12 |
| 35863455 | 2022 | Knockout of UBE2S inhibits the proliferation of gastric cancer cells and induces apoptosis by FAS-mediated death receptor pathway. | 2 |
| 32603752 | 2021 | Comprehensive Investigation into the Role of Ubiquitin-Conjugating Enzyme E2S in Melanoma Development. | 7 |
Citation
Dessen P
UBE2S (ubiquitin conjugating enzyme E2 S)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/42753/ube2s
