Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

XRCC1 (X-ray repair complementing defective repair in Chinese hamster cells 1)

Identity

Other namesRCC
HGNC (Hugo) XRCC1
LocusID (NCBI) 7515
Location 19q13.31
Location_base_pair Starts at 44047464 and ends at 44079730 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)XRCC1   12828
Cards
Entrez_Gene (NCBI)XRCC1  7515  X-ray repair complementing defective repair in Chinese hamster cells 1
GeneCards (Weizmann)XRCC1
Ensembl (Hinxton)ENSG00000073050 [Gene_View]  chr19:44047464-44079730 [Contig_View]  XRCC1 [Vega]
ICGC DataPortalENSG00000073050
AceView (NCBI)XRCC1
Genatlas (Paris)XRCC1
WikiGenes7515
SOURCE (Princeton)NM_006297
Genomic and cartography
GoldenPath (UCSC)XRCC1  -  19q13.31   chr19:44047464-44079730 -  19q13.31   [Description]    (hg19-Feb_2009)
EnsemblXRCC1 - 19q13.31 [CytoView]
Mapping of homologs : NCBIXRCC1 [Mapview]
OMIM194360   
Gene and transcription
Genbank (Entrez)AB208781 AK293542 AK300163 AK315332 BC023593
RefSeq transcript (Entrez)NM_006297
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NG_033799 NT_011109 NW_001838496 NW_004929415
Consensus coding sequences : CCDS (NCBI)XRCC1
Cluster EST : UnigeneHs.98493 [ NCBI ]
CGAP (NCI)Hs.98493
Alternative Splicing : Fast-db (Paris)GSHG0015880
Alternative Splicing GalleryENSG00000073050
Gene ExpressionXRCC1 [ NCBI-GEO ]     XRCC1 [ SEEK ]   XRCC1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP18887 (Uniprot)
NextProtP18887  [Medical]
With graphics : InterProP18887
Splice isoforms : SwissVarP18887 (Swissvar)
Domaine pattern : Prosite (Expaxy)BRCT (PS50172)   
Domains : Interpro (EBI)BRCT_dom    Galactose-bd-like    Xrcc1_N   
Related proteins : CluSTrP18887
Domain families : Pfam (Sanger)BRCT (PF00533)    XRCC1_N (PF01834)   
Domain families : Pfam (NCBI)pfam00533    pfam01834   
Domain families : Smart (EMBL)BRCT (SM00292)  
DMDM Disease mutations7515
Blocks (Seattle)P18887
PDB (SRS)1CDZ    1XNA    1XNT    2D8M    2W3O    3K75    3K77    3LQC   
PDB (PDBSum)1CDZ    1XNA    1XNT    2D8M    2W3O    3K75    3K77    3LQC   
PDB (IMB)1CDZ    1XNA    1XNT    2D8M    2W3O    3K75    3K77    3LQC   
PDB (RSDB)1CDZ    1XNA    1XNT    2D8M    2W3O    3K75    3K77    3LQC   
Human Protein AtlasENSG00000073050
Peptide AtlasP18887
HPRD01909
IPIIPI00002564   IPI01010850   IPI00911037   IPI01010437   
Protein Interaction databases
DIP (DOE-UCLA)P18887
IntAct (EBI)P18887
FunCoupENSG00000073050
BioGRIDXRCC1
InParanoidP18887
Interologous Interaction database P18887
IntegromeDBXRCC1
STRING (EMBL)XRCC1
Ontologies - Pathways
Ontology : AmiGOsingle strand break repair  response to hypoxia  damaged DNA binding  protein binding  nucleus  nucleoplasm  DNA repair  base-excision repair  base-excision repair  response to organic substance  hippocampus development  response to drug  
Ontology : EGO-EBIsingle strand break repair  response to hypoxia  damaged DNA binding  protein binding  nucleus  nucleoplasm  DNA repair  base-excision repair  base-excision repair  response to organic substance  hippocampus development  response to drug  
Pathways : KEGGBase excision repair   
Protein Interaction DatabaseXRCC1
Wikipedia pathwaysXRCC1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)XRCC1
SNP (GeneSNP Utah)XRCC1
SNP : HGBaseXRCC1
Genetic variants : HAPMAPXRCC1
1000_GenomesXRCC1 
ICGC programENSG00000073050 
CONAN: Copy Number AnalysisXRCC1 
Somatic Mutations in Cancer : COSMICXRCC1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Mutations and Diseases : HGMDXRCC1
OMIM194360   
MedgenXRCC1
GENETestsXRCC1
Disease Genetic AssociationXRCC1
Huge Navigator XRCC1 [HugePedia]  XRCC1 [HugeCancerGEM]
Genomic VariantsXRCC1  XRCC1 [DGVbeta]
Exome VariantXRCC1
dbVarXRCC1
ClinVarXRCC1
snp3D : Map Gene to Disease7515
General knowledge
Homologs : HomoloGeneXRCC1
Homology/Alignments : Family Browser (UCSC)XRCC1
Phylogenetic Trees/Animal Genes : TreeFamXRCC1
Chemical/Protein Interactions : CTD7515
Chemical/Pharm GKB GenePA369
Clinical trialXRCC1
Cancer Resource (Charite)ENSG00000073050
Other databases
Probes
Litterature
PubMed499 Pubmed reference(s) in Entrez
CoreMineXRCC1
iHOPXRCC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 13:26:33 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.