XRN2 (5'-3' exoribonuclease 2)

Identity

Other names	-
HGNC	XRN2
Location	20p11.2-p11.1
Location_base_pair	Starts at 21231942 and ends at 21318463 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	XRN2   12836
Entrez_Gene	XRN2  22803  5'-3' exoribonuclease 2
	Cards
GeneCards	XRN2
Ensembl	ENSG00000088930 [Gene_View]  XRN2 [Vega]
Genatlas	XRN2
	Genomic and cartography
GoldenPath	XRN2  -     chr20:21231942-21318463 +  20p11.22   [Description]    (hg18-March_2006)
Ensembl	XRN2 - 20p11.22 [CytoView]
NCBI	Mapview
OMIM	608851 Disease map [OMIM]
HomoloGene	XRN2
	Gene and transcription
Genbank	AF064257 [ ENTREZ ]
Genbank	AF152169 [ ENTREZ ]
Genbank	AK000084 [ ENTREZ ]
Genbank	AK001573 [ ENTREZ ]
Genbank	AK172858 [ ENTREZ ]
RefSeq	NM_012255 [ SRS ]    NM_012255 [ ENTREZ ]
RefSeq	AC_000063 [ SRS ]    AC_000063 [ ENTREZ ]
RefSeq	AC_000152 [ SRS ]    AC_000152 [ ENTREZ ]
RefSeq	NC_000020 [ SRS ]    NC_000020 [ ENTREZ ]
RefSeq	NT_011387 [ SRS ]    NT_011387 [ ENTREZ ]
RefSeq	NW_001838652 [ SRS ]    NW_001838652 [ ENTREZ ]
RefSeq	NW_927317 [ SRS ]    NW_927317 [ ENTREZ ]
CCDS	XRN2 CCDS - NCBI
AceView	XRN2 AceView - NCBI
Unigene	Hs.255932 [ SRS ]    Hs.255932 [ NCBI ]
Fast-db	6622 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9H0D6 [ SRS]    Q9H0D6 [ EXPASY ]     Q9H0D6 [ INTERPRO ]     Q9H0D6 [ UNIPROT ] Q9H0D6 [ VarSplice FASTA ]
Prosite	PS50158 ZF_CCHC [ SRS ]    PS50158 ZF_CCHC [ Expasy ]
Interpro	IPR017151 5_3_exoribonuclease_2 [ SRS ]    IPR017151 5_3_exoribonuclease_2 [ EBI ]
Interpro	IPR004859 Put_53exo [ SRS ]    IPR004859 Put_53exo [ EBI ]
Interpro	IPR001878 Znf_CCHC [ SRS ]    IPR001878 Znf_CCHC [ EBI ]
CluSTr	Q9H0D6
Pfam	PF03159 XRN_N [ SRS ]    PF03159 XRN_N [ Sanger ]    pfam03159 [ NCBI-CDD ]
Smart	SM00343 ZnF_C2HC [EMBL]
Blocks	Q9H0D6
HPRD	10309
	Protein Interaction databases
DIP	Q9H0D6
IntAct	Q9H0D6
	Polymorphism : SNP, mutations, diseases
OMIM	608851    [ map ]
GENETests	608851
SNP	XRN2 [dbSNP-NCBI]
SNP	NM_012255 [SNP-NCI]
SNP	XRN2 [GeneSNPs - Utah]  XRN2] [HGBASE - SRS]
HAPMAP	XRN2 [HAPMAP]
HGMD	XRN2
Genetic Association	XRN2
CDC HuGE	XRN2
	General knowledge
Family Browser	XRN2 [UCSC Family Browser]
SOURCE	NM_012255
SMD	Hs.255932
SAGE	Hs.255932
Enzyme	3.1.13.- [ Enzyme-Expasy ]   3.1.13.- [ Enzyme-SRS ]   3.1.13.- [ IntEnz-EBI ]   3.1.13.- [ BRENDA ]   3.1.13.- [ KEGG ]
GO	DNA catabolic process, exonucleolytic [Amigo]  DNA catabolic process, exonucleolytic
GO	nucleic acid binding [Amigo]  nucleic acid binding
GO	5'-3' exoribonuclease activity [Amigo]  5'-3' exoribonuclease activity
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	nucleolus [Amigo]  nucleolus
GO	transcription [Amigo]  transcription
GO	transcription termination [Amigo]  transcription termination
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	mRNA processing [Amigo]  mRNA processing
GO	RNA catabolic process [Amigo]  RNA catabolic process
GO	spermatogenesis [Amigo]  spermatogenesis
GO	zinc ion binding [Amigo]  zinc ion binding
GO	cell growth [Amigo]  cell growth
GO	hydrolase activity [Amigo]  hydrolase activity
GO	metal ion binding [Amigo]  metal ion binding
PubGene	XRN2
TreeFam	XRN2
CTD	22803 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	XRN2 Related clones (RZPD - Berlin)
	PubMed
PubMed	18 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:19:38 2008