Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZBP1 (Z-DNA binding protein 1)

Identity

Alias (NCBI)C20orf183
DAI
DLM-1
DLM1
HGNC (Hugo) ZBP1
HGNC Alias symbdJ718J7.3
DLM1
DLM-1
DAI
HGNC Alias nameDNA-dependent activator of IRFs
HGNC Previous nameC20orf183
HGNC Previous namechromosome 20 open reading frame 183
LocusID (NCBI) 81030
Atlas_Id 51169
Location 20q13.31  [Link to chromosome band 20q13]
Location_base_pair Starts at 57603852 and ends at 57620426 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RPS6KA5 (14q32.11) / ZBP1 (20q13.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)ZBP1   16176
Cards
Entrez_Gene (NCBI)ZBP1    Z-DNA binding protein 1
AliasesC20orf183; DAI; DLM-1; DLM1
GeneCards (Weizmann)ZBP1
Ensembl hg19 (Hinxton)ENSG00000124256 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124256 [Gene_View]  ENSG00000124256 [Sequence]  chr20:57603852-57620426 [Contig_View]  ZBP1 [Vega]
ICGC DataPortalENSG00000124256
TCGA cBioPortalZBP1
AceView (NCBI)ZBP1
Genatlas (Paris)ZBP1
SOURCE (Princeton)ZBP1
Genetics Home Reference (NIH)ZBP1
Genomic and cartography
GoldenPath hg38 (UCSC)ZBP1  -     chr20:57603852-57620426 -  20q13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZBP1  -     20q13.31   [Description]    (hg19-Feb_2009)
GoldenPathZBP1 - 20q13.31 [CytoView hg19]  ZBP1 - 20q13.31 [CytoView hg38]
ImmunoBaseENSG00000124256
genome Data Viewer NCBIZBP1 [Mapview hg19]  
OMIM606750   
Gene and transcription
Genbank (Entrez)AI659939 AI925506 AJ300575 AK122761 AK128405
RefSeq transcript (Entrez)NM_001160417 NM_001160418 NM_001160419 NM_001323966 NM_030776
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZBP1
Alternative Splicing GalleryENSG00000124256
Gene ExpressionZBP1 [ NCBI-GEO ]   ZBP1 [ EBI - ARRAY_EXPRESS ]   ZBP1 [ SEEK ]   ZBP1 [ MEM ]
Gene Expression Viewer (FireBrowse)ZBP1 [ Firebrowse - Broad ]
GenevisibleExpression of ZBP1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81030
GTEX Portal (Tissue expression)ZBP1
Human Protein AtlasENSG00000124256-ZBP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H171   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H171  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H171
Splice isoforms : SwissVarQ9H171
PhosPhoSitePlusQ9H171
Domaine pattern : Prosite (Expaxy)Z_BINDING (PS50139)   
Domains : Interpro (EBI)WH-like_DNA-bd_sf    WH_DNA-bd_sf    Zalpha_dom    ZBP1   
Domain families : Pfam (Sanger)z-alpha (PF02295)   
Domain families : Pfam (NCBI)pfam02295   
Domain families : Smart (EMBL)Zalpha (SM00550)  
Conserved Domain (NCBI)ZBP1
Blocks (Seattle)ZBP1
PDB (RSDB)2L4M    2LNB    3EYI    4KA4   
PDB Europe2L4M    2LNB    3EYI    4KA4   
PDB (PDBSum)2L4M    2LNB    3EYI    4KA4   
PDB (IMB)2L4M    2LNB    3EYI    4KA4   
Structural Biology KnowledgeBase2L4M    2LNB    3EYI    4KA4   
SCOP (Structural Classification of Proteins)2L4M    2LNB    3EYI    4KA4   
CATH (Classification of proteins structures)2L4M    2LNB    3EYI    4KA4   
SuperfamilyQ9H171
Human Protein Atlas [tissue]ENSG00000124256-ZBP1 [tissue]
Peptide AtlasQ9H171
HPRD09484
IPIIPI00006512   IPI00219702   IPI00219704   IPI00334653   IPI00181608   IPI00844531   IPI00930211   IPI00843852   IPI00930657   
Protein Interaction databases
DIP (DOE-UCLA)Q9H171
IntAct (EBI)Q9H171
BioGRIDZBP1
STRING (EMBL)ZBP1
ZODIACZBP1
Ontologies - Pathways
QuickGOQ9H171
Ontology : AmiGOactivation of innate immune response  DNA binding  DNA binding  left-handed Z-DNA binding  double-stranded RNA binding  protein binding  nucleus  nucleus  cytoplasm  cytosol  cytosol  apoptotic process  viral process  regulation of type I interferon production  positive regulation of type I interferon production  positive regulation of apoptotic process  innate immune response  regulation of inflammatory response  positive regulation of inflammatory response  defense response to virus  positive regulation of type I interferon-mediated signaling pathway  positive regulation of necroptotic process  pyroptosis  regulation of interleukin-1-mediated signaling pathway  
Ontology : EGO-EBIactivation of innate immune response  DNA binding  DNA binding  left-handed Z-DNA binding  double-stranded RNA binding  protein binding  nucleus  nucleus  cytoplasm  cytosol  cytosol  apoptotic process  viral process  regulation of type I interferon production  positive regulation of type I interferon production  positive regulation of apoptotic process  innate immune response  regulation of inflammatory response  positive regulation of inflammatory response  defense response to virus  positive regulation of type I interferon-mediated signaling pathway  positive regulation of necroptotic process  pyroptosis  regulation of interleukin-1-mediated signaling pathway  
Pathways : KEGGCytosolic DNA-sensing pathway   
NDEx NetworkZBP1
Atlas of Cancer Signalling NetworkZBP1
Wikipedia pathwaysZBP1
Orthology - Evolution
OrthoDB81030
GeneTree (enSembl)ENSG00000124256
Phylogenetic Trees/Animal Genes : TreeFamZBP1
HOGENOMQ9H171
Homologs : HomoloGeneZBP1
Homology/Alignments : Family Browser (UCSC)ZBP1
Gene fusions - Rearrangements
Fusion : QuiverZBP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBP1 [hg38]
dbVarZBP1
ClinVarZBP1
MonarchZBP1
1000_GenomesZBP1 
Exome Variant ServerZBP1
GNOMAD BrowserENSG00000124256
Varsome BrowserZBP1
Genomic Variants (DGV)ZBP1 [DGVbeta]
DECIPHERZBP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZBP1 
Mutations
ICGC Data PortalZBP1 
TCGA Data PortalZBP1 
Broad Tumor PortalZBP1
OASIS PortalZBP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZBP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZBP1
Mutations and Diseases : HGMDZBP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZBP1
DgiDB (Drug Gene Interaction Database)ZBP1
DoCM (Curated mutations)ZBP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZBP1 (select a term)
intoGenZBP1
Cancer3DZBP1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606750   
Orphanet
DisGeNETZBP1
MedgenZBP1
Genetic Testing Registry ZBP1
NextProtQ9H171 [Medical]
GENETestsZBP1
Target ValidationZBP1
Huge Navigator ZBP1 [HugePedia]
ClinGenZBP1
Clinical trials, drugs, therapy
MyCancerGenomeZBP1
Protein Interactions : CTD
Pharm GKB GenePA38094
PharosQ9H171
Clinical trialZBP1
Miscellaneous
canSAR (ICR)ZBP1 (select the gene name)
HarmonizomeZBP1
DataMed IndexZBP1
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZBP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:53:22 CET 2021

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