Identity
HGNC
LOCATION
20q13.31
LOCUSID
ALIAS
C20orf183,DAI,DLM-1,DLM1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 81030
MIM: 606750
HGNC: 16176
Ensembl: ENSG00000124256
Variants:
dbSNP: 81030
ClinVar: 81030
TCGA: ENSG00000124256
COSMIC: ZBP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000124256 | ENST00000371173 | Q9H171 |
| ENSG00000124256 | ENST00000395822 | Q9H171 |
| ENSG00000124256 | ENST00000453793 | H0Y6D1 |
| ENSG00000124256 | ENST00000541799 | Q9H171 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37725754 | 2024 | Bile acid-induced IRF3 phosphorylation mediates cell death, inflammatory responses, and fibrosis in cholestasis-induced liver and kidney injury via regulation of ZBP1. | 6 |
| 38331384 | 2024 | ZBP1 promotes hepatocyte pyroptosis in acute liver injury by regulating the PGAM5/ROS pathway. | 0 |
| 38369516 | 2024 | The innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer. | 0 |
| 38493248 | 2024 | Sensing of mitochondrial DNA by ZBP1 promotes RIPK3-mediated necroptosis and ferroptosis in response to diquat poisoning. | 1 |
| 37725754 | 2024 | Bile acid-induced IRF3 phosphorylation mediates cell death, inflammatory responses, and fibrosis in cholestasis-induced liver and kidney injury via regulation of ZBP1. | 6 |
| 38331384 | 2024 | ZBP1 promotes hepatocyte pyroptosis in acute liver injury by regulating the PGAM5/ROS pathway. | 0 |
| 38369516 | 2024 | The innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer. | 0 |
| 38493248 | 2024 | Sensing of mitochondrial DNA by ZBP1 promotes RIPK3-mediated necroptosis and ferroptosis in response to diquat poisoning. | 1 |
| 36710220 | 2023 | ADAR1 and ZBP1 in innate immunity, cell death, and disease. | 21 |
| 36755096 | 2023 | Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis. | 27 |
| 37267644 | 2023 | PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis. | 10 |
| 37276820 | 2023 | Z-form nucleic acid-binding protein 1 (ZBP1) as a sensor of viral and cellular Z-RNAs: walking the razor's edge. | 5 |
| 37587292 | 2023 | Heartbreakers: innate sensors ZBP1 and cGAS linked to cardiotoxicity. | 1 |
| 36710220 | 2023 | ADAR1 and ZBP1 in innate immunity, cell death, and disease. | 21 |
| 36755096 | 2023 | Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis. | 27 |
Citation
Dessen P
ZBP1 (Z-DNA binding protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-10-01
Online version: http://atlasgeneticsoncology.org/gene/51169/zbp1
