| Nomenclature |
|---|
| HGNC (Hugo) | ZFP36 12862 |
| Cards |
|---|
| Entrez_Gene (NCBI) | ZFP36 7538 ZFP36 ring finger protein |
| Aliases | G0S24; GOS24; NUP475; RNF162A; |
| TIS11; TTP; zfp-36 |
| GeneCards (Weizmann) | ZFP36 |
| Ensembl hg19 (Hinxton) | ENSG00000128016 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000128016 [Gene_View] ENSG00000128016 [Sequence] chr19:39406847-39409412 [Contig_View] ZFP36 [Vega] |
| ICGC DataPortal | ENSG00000128016 |
| TCGA cBioPortal | ZFP36 |
| AceView (NCBI) | ZFP36 |
| Genatlas (Paris) | ZFP36 |
| WikiGenes | 7538 |
| SOURCE (Princeton) | ZFP36 |
| Genetics Home Reference (NIH) | ZFP36 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | ZFP36 - chr19:39406847-39409412 + 19q13.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | ZFP36 - 19q13.2 [Description] (hg19-Feb_2009) |
| Ensembl | ZFP36 - 19q13.2 [CytoView hg19] ZFP36 - 19q13.2 [CytoView hg38] |
| Mapping of homologs : NCBI | ZFP36 [Mapview hg19] ZFP36 [Mapview hg38] |
| OMIM | 190700 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AJ227917 AK314042 BC009693 BM055332 M63625 |
| RefSeq transcript (Entrez) | NM_003407 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | ZFP36 |
| Cluster EST : Unigene | Hs.534052 [ NCBI ] |
| CGAP (NCI) | Hs.534052 |
| Alternative Splicing Gallery | ENSG00000128016 |
| Gene Expression | ZFP36 [ NCBI-GEO ] ZFP36 [ EBI - ARRAY_EXPRESS ]
ZFP36 [ SEEK ] ZFP36 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | ZFP36 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 7538 |
| GTEX Portal (Tissue expression) | ZFP36 |
| Human Protein Atlas | ENSG00000128016-ZFP36 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P26651 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P26651 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P26651 |
| Splice isoforms : SwissVar | P26651 |
| PhosPhoSitePlus | P26651 |
| Domaine pattern : Prosite (Expaxy) | ZF_C3H1 (PS50103) |
| Domains : Interpro (EBI) | Znf_CCCH Znf_CCCH_sf |
| Domain families : Pfam (Sanger) | zf-CCCH (PF00642) |
| Domain families : Pfam (NCBI) | pfam00642 |
| Domain families : Smart (EMBL) | ZnF_C3H1 (SM00356) |
| Conserved Domain (NCBI) | ZFP36 |
| DMDM Disease mutations | 7538 |
| Blocks (Seattle) | ZFP36 |
| PDB (SRS) | 4J8S |
| PDB (PDBSum) | 4J8S |
| PDB (IMB) | 4J8S |
| PDB (RSDB) | 4J8S |
| Structural Biology KnowledgeBase | 4J8S |
| SCOP (Structural Classification of Proteins) | 4J8S |
| CATH (Classification of proteins structures) | 4J8S |
| Superfamily | P26651 |
| Human Protein Atlas [tissue] | ENSG00000128016-ZFP36 [tissue] |
| Peptide Atlas | P26651 |
| HPRD | 01835 |
| IPI | IPI00000893 IPI00976735 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P26651 |
| IntAct (EBI) | P26651 |
| FunCoup | ENSG00000128016 |
| BioGRID | ZFP36 |
| STRING (EMBL) | ZFP36 |
| ZODIAC | ZFP36 |
| Ontologies - Pathways |
|---|
| QuickGO | P26651 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II MAPK cascade MAPK cascade exosome (RNase complex) nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nuclear-transcribed mRNA poly(A) tail shortening P-body DNA binding RNA binding single-stranded RNA binding mRNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm cytosol cytosol cytosol mRNA catabolic process response to wounding response to wounding cytoplasmic stress granule regulation of keratinocyte proliferation AU-rich element binding AU-rich element binding enzyme binding protein kinase binding C-C chemokine binding CCR4-NOT complex heat shock protein binding nuclear-transcribed mRNA catabolic process, deadenylation-independent decay regulation of tumor necrosis factor production negative regulation of viral transcription miRNA mediated inhibition of translation mRNA 3'-UTR AU-rich region binding p38MAPK cascade response to starvation regulation of mRNA stability regulation of mRNA stability regulation of mRNA stability cellular response to fibroblast growth factor stimulus negative regulation of interleukin-2 biosynthetic process positive regulation of fat cell differentiation regulation of keratinocyte differentiation negative regulation of erythrocyte differentiation metal ion binding mRNA transport positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 3'-UTR-mediated mRNA destabilization 3'-UTR-mediated mRNA destabilization 3'-UTR-mediated mRNA destabilization RNA polymerase binding RISC-loading complex 3'-UTR-mediated mRNA stabilization cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus cellular response to glucocorticoid stimulus 14-3-3 protein binding cellular response to granulocyte macrophage colony-stimulating factor stimulus Dcp1-Dcp2 complex positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA regulation of keratinocyte apoptotic process negative regulation of polynucleotide adenylyltransferase activity positive regulation of intracellular mRNA localization ribonucleoprotein complex positive regulation of gene silencing by miRNA |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II MAPK cascade MAPK cascade exosome (RNase complex) nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nuclear-transcribed mRNA poly(A) tail shortening P-body DNA binding RNA binding single-stranded RNA binding mRNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm cytosol cytosol cytosol mRNA catabolic process response to wounding response to wounding cytoplasmic stress granule regulation of keratinocyte proliferation AU-rich element binding AU-rich element binding enzyme binding protein kinase binding C-C chemokine binding CCR4-NOT complex heat shock protein binding nuclear-transcribed mRNA catabolic process, deadenylation-independent decay regulation of tumor necrosis factor production negative regulation of viral transcription miRNA mediated inhibition of translation mRNA 3'-UTR AU-rich region binding p38MAPK cascade response to starvation regulation of mRNA stability regulation of mRNA stability regulation of mRNA stability cellular response to fibroblast growth factor stimulus negative regulation of interleukin-2 biosynthetic process positive regulation of fat cell differentiation regulation of keratinocyte differentiation negative regulation of erythrocyte differentiation metal ion binding mRNA transport positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 3'-UTR-mediated mRNA destabilization 3'-UTR-mediated mRNA destabilization 3'-UTR-mediated mRNA destabilization RNA polymerase binding RISC-loading complex 3'-UTR-mediated mRNA stabilization cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus cellular response to glucocorticoid stimulus 14-3-3 protein binding cellular response to granulocyte macrophage colony-stimulating factor stimulus Dcp1-Dcp2 complex positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA regulation of keratinocyte apoptotic process negative regulation of polynucleotide adenylyltransferase activity positive regulation of intracellular mRNA localization ribonucleoprotein complex positive regulation of gene silencing by miRNA |
| Pathways : KEGG | HTLV-I infection |
| NDEx Network | ZFP36 |
| Atlas of Cancer Signalling Network | ZFP36 |
| Wikipedia pathways | ZFP36 |
| Orthology - Evolution |
|---|
| OrthoDB | 7538 |
| GeneTree (enSembl) | ENSG00000128016 |
| Phylogenetic Trees/Animal Genes : TreeFam | ZFP36 |
| HOVERGEN | P26651 |
| HOGENOM | P26651 |
| Homologs : HomoloGene | ZFP36 |
| Homology/Alignments : Family Browser (UCSC) | ZFP36 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | ZFP36/FOSB [19q13.2/19q13.32] |
| Fusion : Quiver | ZFP36 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | ZFP36 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | ZFP36 |
| dbVar | ZFP36 |
| ClinVar | ZFP36 |
| 1000_Genomes | ZFP36 |
| Exome Variant Server | ZFP36 |
| ExAC (Exome Aggregation Consortium) | ENSG00000128016 |
| GNOMAD Browser | ENSG00000128016 |
| Varsome Browser | ZFP36 |
| Genetic variants : HAPMAP | 7538 |
| Genomic Variants (DGV) | ZFP36 [DGVbeta] |
| DECIPHER | ZFP36 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | ZFP36 |
| Mutations |
|---|
| ICGC Data Portal | ZFP36 |
| TCGA Data Portal | ZFP36 |
| Broad Tumor Portal | ZFP36 |
| OASIS Portal | ZFP36 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | ZFP36 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | ZFP36 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search ZFP36 |
| DgiDB (Drug Gene Interaction Database) | ZFP36 |
| DoCM (Curated mutations) | ZFP36 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | ZFP36 (select a term) |
| intoGen | ZFP36 |
| Cancer3D | ZFP36(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 190700 |
| Orphanet | |
| DisGeNET | ZFP36 |
| Medgen | ZFP36 |
| Genetic Testing Registry | ZFP36
|
| NextProt | P26651 [Medical] |
| TSGene | 7538 |
| GENETests | ZFP36 |
| Target Validation | ZFP36 |
| Huge Navigator |
ZFP36 [HugePedia] |
| snp3D : Map Gene to Disease | 7538 |
| BioCentury BCIQ | ZFP36 |
| ClinGen | ZFP36 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 7538 |
| Chemical/Pharm GKB Gene | PA37451 |
| Clinical trial | ZFP36 |
| Miscellaneous |
|---|
| canSAR (ICR) | ZFP36 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 182 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | ZFP36 |
| EVEX | ZFP36 |
| GoPubMed | ZFP36 |
| iHOP | ZFP36 |
