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ZMPSTE24 (zinc metallopeptidase STE24)

Identity

Other namesFACE-1
FACE1
HGPS
PRO1
STE24
Ste24p
HGNC (Hugo) ZMPSTE24
LocusID (NCBI) 10269
Location 1p34.2
Location_base_pair Starts at 40723722 and ends at 40759856 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ZMPSTE24   12877
Cards
Entrez_Gene (NCBI)ZMPSTE24  10269  zinc metallopeptidase STE24
GeneCards (Weizmann)ZMPSTE24
Ensembl (Hinxton)ENSG00000084073 [Gene_View]  chr1:40723722-40759856 [Contig_View]  ZMPSTE24 [Vega]
AceView (NCBI)ZMPSTE24
Genatlas (Paris)ZMPSTE24
WikiGenes10269
SOURCE (Princeton)NM_005857
Genomic and cartography
GoldenPath (UCSC)ZMPSTE24  -  1p34.2   chr1:40723722-40759856 +  1p34.2   [Description]    (hg19-Feb_2009)
EnsemblZMPSTE24 - 1p34.2 [CytoView]
Mapping of homologs : NCBIZMPSTE24 [Mapview]
OMIM176670   275210   606480   608612   
Gene and transcription
Genbank (Entrez)AA436253 AB016068 AF064867 AI003768 AK027874
RefSeq transcript (Entrez)NM_005857
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_008695 NT_032977 NW_001838577 NW_004929290
Consensus coding sequences : CCDS (NCBI)ZMPSTE24
Cluster EST : UnigeneHs.721062 [ NCBI ]
CGAP (NCI)Hs.721062
Alternative Splicing : Fast-db (Paris)GSHG0000414
Alternative Splicing GalleryENSG00000084073
Gene ExpressionZMPSTE24 [ NCBI-GEO ]     ZMPSTE24 [ SEEK ]   ZMPSTE24 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75844 (Uniprot)
NextProtO75844  [Medical]
With graphics : InterProO75844
Splice isoforms : SwissVarO75844 (Swissvar)
Catalytic activity : Enzyme3.4.24.84 [ Enzyme-Expasy ]   3.4.24.843.4.24.84 [ IntEnz-EBI ]   3.4.24.84 [ BRENDA ]   3.4.24.84 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)ZINC_PROTEASE (PS00142)   
Domains : Interpro (EBI)CAXX_Prtase_1    Peptidase_M48   
Related proteins : CluSTrO75844
Domain families : Pfam (Sanger)Peptidase_M48 (PF01435)   
Domain families : Pfam (NCBI)pfam01435   
DMDM Disease mutations10269
Blocks (Seattle)O75844
PDB (SRS)2YPT    4AW6   
PDB (PDBSum)2YPT    4AW6   
PDB (IMB)2YPT    4AW6   
PDB (RSDB)2YPT    4AW6   
Human Protein AtlasENSG00000084073
Peptide AtlasO75844
HPRD07349
IPIIPI00027180   
Protein Interaction databases
DIP (DOE-UCLA)O75844
IntAct (EBI)O75844
FunCoupENSG00000084073
BioGRIDZMPSTE24
InParanoidO75844
Interologous Interaction database O75844
IntegromeDBZMPSTE24
STRING (EMBL)ZMPSTE24
Ontologies - Pathways
Ontology : AmiGOmetalloendopeptidase activity  nuclear inner membrane  endoplasmic reticulum membrane  proteolysis  nuclear envelope organization  metalloexopeptidase activity  integral to membrane  prenylated protein catabolic process  metal ion binding  CAAX-box protein processing  
Ontology : EGO-EBImetalloendopeptidase activity  nuclear inner membrane  endoplasmic reticulum membrane  proteolysis  nuclear envelope organization  metalloexopeptidase activity  integral to membrane  prenylated protein catabolic process  metal ion binding  CAAX-box protein processing  
Pathways : KEGGTerpenoid backbone biosynthesis   
REACTOMEZMPSTE24
Protein Interaction DatabaseZMPSTE24
Wikipedia pathwaysZMPSTE24
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ZMPSTE24
SNP (GeneSNP Utah)ZMPSTE24
SNP : HGBaseZMPSTE24
Genetic variants : HAPMAPZMPSTE24
1000_GenomesZMPSTE24 
ICGC programENSG00000084073 
Somatic Mutations in Cancer : COSMICZMPSTE24 
CONAN: Copy Number AnalysisZMPSTE24 
Mutations and Diseases : HGMDZMPSTE24
OMIM176670    275210    606480    608612   
GENETestsZMPSTE24
Disease Genetic AssociationZMPSTE24
Huge Navigator ZMPSTE24 [HugePedia]  ZMPSTE24 [HugeCancerGEM]
Genomic VariantsZMPSTE24  ZMPSTE24 [DGVbeta]
Exome VariantZMPSTE24
dbVarZMPSTE24
ClinVarZMPSTE24
snp3D : Map Gene to Disease10269
General knowledge
Homologs : HomoloGeneZMPSTE24
Homology/Alignments : Family Browser (UCSC)ZMPSTE24
Phylogenetic Trees/Animal Genes : TreeFamZMPSTE24
Chemical/Protein Interactions : CTD10269
Chemical/Pharm GKB GenePA37466
Clinical trialZMPSTE24
Cancer Resource (Charite)ENSG00000084073
Other databases
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
CoreMineZMPSTE24
iHOPZMPSTE24
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Mar 31 09:22:14 CEST 2014

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