Atlas of Genetics and Cytogenetics in Oncology and Haematology

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del(19)(p13p13) DNAJB1/PRKACA

(Note : for Links provided by Atlas : click)


Atlas_Id 100019
Phylum Digestive organs: Liver::
WHO/OMS Classification Digestive organs
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Liver: Adenocarcinoma

Genes involved and Proteins

Gene NameDNAJB1
Location 19p13.12

Location 19p13.12


Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma
Honeyman JN, Simon EP, Robine N, Chiaroni-Clarke R, Darcy DG, Lim II, Gleason CE, Murphy JM, Rosenberg BR, Teegan L, Takacs CN, Botero S, Belote R, Germer S, Emde AK, Vacic V, Bhanot U, LaQuaglia MP, Simon SM
Science 2014 Feb 28;343(6174):1010-4
PMID 24578576
The genomic landscape of fibrolamellar hepatocellular carcinoma: whole genome sequencing of ten patients
Darcy DG, Chiaroni-Clarke R, Murphy JM, Honeyman JN, Bhanot U, LaQuaglia MP, Simon SM
Oncotarget 2015 Jan 20;6(2):755-70
PMID 25605237

Translocations implicated (Data extracted from papers in the Atlas)

 del(19)(p13p13) DNAJB1/PRKACA

External links

Mitelman database del(19)(p13p13) [CaseList]     del(19)(p13p13) [Transloc - MCList]   DNAJB1/PRKACA Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databasedel(19)(p13p13) DNAJB1/PRKACA
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Mon Dec 14 18:31:02 CET 2020

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