del(19)(p13p13) DNAJB1/PRKACA

Identity

Atlas_Id	100019
Phylum	Digestive organs: Liver::
WHO/OMS Classification	Digestive organs
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Liver: Adenocarcinoma

Genes involved and Proteins

Gene Name	DNAJB1
Location	19p13.12

Gene Name	PRKACA
Location	19p13.12

Bibliography

Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma

Honeyman JN, Simon EP, Robine N, Chiaroni-Clarke R, Darcy DG, Lim II, Gleason CE, Murphy JM, Rosenberg BR, Teegan L, Takacs CN, Botero S, Belote R, Germer S, Emde AK, Vacic V, Bhanot U, LaQuaglia MP, Simon SM

Science 2014 Feb 28;343(6174):1010-4

PMID 24578576

The genomic landscape of fibrolamellar hepatocellular carcinoma: whole genome sequencing of ten patients

Darcy DG, Chiaroni-Clarke R, Murphy JM, Honeyman JN, Bhanot U, LaQuaglia MP, Simon SM

Oncotarget 2015 Jan 20;6(2):755-70

PMID 25605237

Translocations implicated (Data extracted from papers in the Atlas)

	del(19)(p13p13) DNAJB1/PRKACA

External links

Mitelman database	del(19)(p13p13) [CaseList]     del(19)(p13p13) [Transloc - MCList]   DNAJB1/PRKACA Fusion - MCList]
COSMIC	[ DNAJB1 ]   [ PRKACA ]
arrayMap	arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease database	del(19)(p13p13) DNAJB1/PRKACA

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Jul 8 15:32:49 CEST 2019

For comments and suggestions or contributions, please contact us