Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

t(2;7)(q23;p12) RIF1/PKD1L1

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 105503
Phylum Female organs: Breast::
WHO/OMS Classification Female organs
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Breast: Adenocarcinoma

Genes involved and Proteins

Gene NameRIF1
Location 2q23.3

Gene NamePKD1L1
Location 7p12.3


Array painting reveals a high frequency of balanced translocations in breast cancer cell lines that break in cancer-relevant genes
Howarth KD, Blood KA, Ng BL, Beavis JC, Chua Y, Cooke SL, Raby S, Ichimura K, Collins VP, Carter NP, Edwards PA
Oncogene 2008 May 22;27(23):3345-59
PMID 18084325

Translocations implicated (Data extracted from papers in the Atlas)

 t(2;7)(q23;p12) RIF1/PKD1L1

External links

Mitelman database t(2;7)(q23;p12) [CaseList]     t(2;7)(q23;p12) [Transloc - MCList]   RIF1/PKD1L1 Fusion - MCList]
COSMIC[ RIF1 ]   [ PKD1L1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(2;7)(q23;p12) RIF1/PKD1L1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Feb 14 17:49:11 CET 2019

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us