Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(12;18)(q14;q12) HMGA2/SETBP1

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Atlas_Id 101533
Phylum Soft Tissues: Soft Tissues::
WHO/OMS Classification Soft Tissues
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Soft Tissues: Adipocytic tumor, special type

Disease Soft Tissues: Lipoma

Genes involved and Proteins

Gene NameHMGA2
Location 12q14.3

Gene NameSETBP1
Location 18q12.3


The recurrent chromosomal translocation t(12;18)(q14~15;q12~21) causes the fusion gene HMGA2-SETBP1 and HMGA2 expression in lipoma and osteochondrolipoma
Panagopoulos I, Gorunova L, Bjerkehagen B, Lobmaier I, Heim S
Int J Oncol 2015 Sep;47(3):884-90
PMID 26202160

Translocations implicated (Data extracted from papers in the Atlas)

 t(12;18)(q14;q12) HMGA2/SETBP1

External links

Mitelman database t(12;18)(q14;q12) [CaseList]     t(12;18)(q14;q12) [Transloc - MCList]   HMGA2/SETBP1 Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(12;18)(q14;q12) HMGA2/SETBP1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Mon Dec 14 18:52:55 CET 2020

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