| Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| Atlas_Id | 101533 |
| Phylum | Soft Tissues: Soft Tissues:: |
| WHO/OMS Classification | Soft Tissues |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Soft Tissues: Adipocytic tumor, special type |
| Disease | Soft Tissues: Lipoma |
| Genes involved and Proteins |
| Gene Name | HMGA2 |
| Location | 12q14.3 |
| Gene Name | SETBP1 |
| Location | 18q12.3 |
| Bibliography |
| The recurrent chromosomal translocation t(12;18)(q14~15;q12~21) causes the fusion gene HMGA2-SETBP1 and HMGA2 expression in lipoma and osteochondrolipoma |
| Panagopoulos I, Gorunova L, Bjerkehagen B, Lobmaier I, Heim S |
| Int J Oncol 2015 Sep;47(3):884-90 |
| PMID 26202160 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(12;18)(q14;q12) HMGA2/SETBP1 | |
| External links |
| Mitelman database | t(12;18)(q14;q12) [Fusion] t(12;18)(q14;q12) [Cytogenetics Case] |
| COSMIC | [ HMGA2 ] [ SETBP1 ] |
| Disease database | t(12;18)(q14;q12) HMGA2/SETBP1 |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Jul 13 11:22:53 CEST 2020 |
For comments and suggestions or contributions, please contact us