t(15;15)(q21;q25) MYO5A/NTRK3

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

Location

15q21.2

Gene name

Location

15q25.3

Highly cited references

Pubmed IDYearTitleCitations
274773202016NTRK3 kinase fusions in Spitz tumours.40
284330762017Identification of NTRK3 Fusions in Childhood Melanocytic Neoplasms.12
304752552019Distinct Genomic Patterns in Pigmented Epithelioid Melanocytoma: A Molecular and Histologic Analysis of 16 Cases.7
329681852021Fusion partners of NTRK3 affect subcellular localization of the fusion kinase and cytomorphology of melanocytes.5
325569252020Central nervous system ganglioneuroblastoma harboring MYO5A-NTRK3 fusion.1

Bibliography

Pubmed IDLast YearTitleAuthors
274773202016NTRK3 kinase fusions in Spitz tumours.Yeh I et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(15;15)(q21;q25) MYO5A/NTRK3

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/101967/t(15;15)(q21;q25)-myo5a-ntrk3