MYCL (MYCL proto-oncogene, bHLH transcription factor)

2003-02-01  

Identity

HGNC
MYCL
LOCATION
1p34.2
LOCUSID
4610
ALIAS
L-Myc,LMYC,MYCL1,bHLHe38
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4610
MIM: 164850
HGNC: 7555
Ensembl: ENSG00000116990

Variants:

dbSNP: 4610
ClinVar: 4610
TCGA: ENSG00000116990
COSMIC: MYCL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116990ENST00000372815P12524
ENSG00000116990ENST00000372816P12524
ENSG00000116990ENST00000397332P12524
ENSG00000116990ENST00000450953E9PQS5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
378271802023Comparative study on the mutation spectrum of L-MYC and C-MYC genes of blood cfDNA in patients with ovarian cancer and healthy females.0
378271802023Comparative study on the mutation spectrum of L-MYC and C-MYC genes of blood cfDNA in patients with ovarian cancer and healthy females.0
361779002022MYCL promotes the progression of triple‑negative breast cancer by activating the JAK/STAT3 pathway.1
361779002022MYCL promotes the progression of triple‑negative breast cancer by activating the JAK/STAT3 pathway.1
342576192021MYCL1 Amplification and Expression of L-Myc and c-Myc in Surgically Resected Small-Cell Lung Carcinoma.3
349309322021MYCL promotes iPSC-like colony formation via MYC Box 0 and 2 domains.1
342576192021MYCL1 Amplification and Expression of L-Myc and c-Myc in Surgically Resected Small-Cell Lung Carcinoma.3
349309322021MYCL promotes iPSC-like colony formation via MYC Box 0 and 2 domains.1
310254042019Targeted silencing of MYCL1 by RNA interference inhibits migration and invasion of MGC-803 gastric cancer cells.1
310254042019Targeted silencing of MYCL1 by RNA interference inhibits migration and invasion of MGC-803 gastric cancer cells.1
255285832015Expression and prognostic value of Mycl1 in gastric cancer.8
255285832015Expression and prognostic value of Mycl1 in gastric cancer.8
233490192013Association of polymorphisms and haplotype in the region of TRIT1, MYCL1 and MFSD2A with the risk and clinicopathological features of gastric cancer in a southeast Chinese population.9
233490192013Association of polymorphisms and haplotype in the region of TRIT1, MYCL1 and MFSD2A with the risk and clinicopathological features of gastric cancer in a southeast Chinese population.9
224908492012[Association between H-ras and L-myc gene polymorphisms and susceptibility to colorectal cancer].1

Citation

Dessen P

MYCL (MYCL proto-oncogene, bHLH transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/170/gene-fusions/haematological-explorer/gene-explorer/