CD300A (CD300a molecule)

2003-08-01  

Identity

HGNC
LOCATION
17q25.1
LOCUSID
ALIAS
CLM-8,CMRF-35-H9,CMRF-35H,CMRF35-H,CMRF35-H9,CMRF35H,CMRF35H9,IGSF12,IRC1,IRC1/IRC2,IRC2,IRp60

Other Information

Locus ID:

NCBI: 11314
MIM: 606790
HGNC: 19319
Ensembl: ENSG00000167851

Variants:

dbSNP: 11314
ClinVar: 11314
TCGA: ENSG00000167851
COSMIC: CD300A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167851ENST00000310828Q9UGN4
ENSG00000167851ENST00000360141Q9UGN4
ENSG00000167851ENST00000361933Q9UGN4
ENSG00000167851ENST00000392625Q9UGN4
ENSG00000167851ENST00000577511J3QKQ4
ENSG00000167851ENST00000648095J3QKQ4

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
335485782021CD300a and CD300f molecules regulate the function of leukocytes.7
335485782021CD300a and CD300f molecules regulate the function of leukocytes.7
304854142019CD300 receptor family in viral infections.18
304854142019CD300 receptor family in viral infections.18
264685292016The Phosphatidylserine and Phosphatidylethanolamine Receptor CD300a Binds Dengue Virus and Enhances Infection.51
265819922016Pseudorabies Virus US3 Protein Kinase Protects Infected Cells from NK Cell-Mediated Lysis via Increased Binding of the Inhibitory NK Cell Receptor CD300a.16
270403282016CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition.15
264685292016The Phosphatidylserine and Phosphatidylethanolamine Receptor CD300a Binds Dengue Virus and Enhances Infection.51
265819922016Pseudorabies Virus US3 Protein Kinase Protects Infected Cells from NK Cell-Mediated Lysis via Increased Binding of the Inhibitory NK Cell Receptor CD300a.16
270403282016CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition.15
264354772015Suppression of CD300A inhibits the growth of diffuse large B-cell lymphoma.8
264354772015Suppression of CD300A inhibits the growth of diffuse large B-cell lymphoma.8
241317922014Identification of CD300a as a new hypoxia-inducible gene and a regulator of CCL20 and VEGF production by human monocytes and macrophages.14
248154242014Mechanism of phosphatidylserine inhibition of IgE/FcεRI-dependent anaphylactic human basophil degranulation via CD300a.9
249584592014PPARβ/δ activation of CD300a controls intestinal immunity.17

Citation

Dessen P

CD300A (CD300a molecule)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/40111/img/css/lib/haematological-explorer/