CD300A (CD300a molecule)

2003-08-01  

Identity

HGNC
CD300A
LOCATION
17q25.1
LOCUSID
11314
ALIAS
CLM-8,CMRF-35-H9,CMRF-35H,CMRF35-H,CMRF35-H9,CMRF35H,CMRF35H9,IGSF12,IRC1,IRC1/IRC2,IRC2,IRp60

Other Information

Locus ID:

NCBI: 11314
MIM: 606790
HGNC: 19319
Ensembl: ENSG00000167851

Variants:

dbSNP: 11314
ClinVar: 11314
TCGA: ENSG00000167851
COSMIC: CD300A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167851ENST00000310828Q9UGN4
ENSG00000167851ENST00000360141Q9UGN4
ENSG00000167851ENST00000361933Q9UGN4
ENSG00000167851ENST00000392625Q9UGN4
ENSG00000167851ENST00000577511J3QKQ4
ENSG00000167851ENST00000648095J3QKQ4

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
335485782021CD300a and CD300f molecules regulate the function of leukocytes.7
335485782021CD300a and CD300f molecules regulate the function of leukocytes.7
304854142019CD300 receptor family in viral infections.18
304854142019CD300 receptor family in viral infections.18
264685292016The Phosphatidylserine and Phosphatidylethanolamine Receptor CD300a Binds Dengue Virus and Enhances Infection.51
265819922016Pseudorabies Virus US3 Protein Kinase Protects Infected Cells from NK Cell-Mediated Lysis via Increased Binding of the Inhibitory NK Cell Receptor CD300a.16
270403282016CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition.15
264685292016The Phosphatidylserine and Phosphatidylethanolamine Receptor CD300a Binds Dengue Virus and Enhances Infection.51
265819922016Pseudorabies Virus US3 Protein Kinase Protects Infected Cells from NK Cell-Mediated Lysis via Increased Binding of the Inhibitory NK Cell Receptor CD300a.16
270403282016CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition.15
264354772015Suppression of CD300A inhibits the growth of diffuse large B-cell lymphoma.8
264354772015Suppression of CD300A inhibits the growth of diffuse large B-cell lymphoma.8
241317922014Identification of CD300a as a new hypoxia-inducible gene and a regulator of CCL20 and VEGF production by human monocytes and macrophages.14
248154242014Mechanism of phosphatidylserine inhibition of IgE/FcεRI-dependent anaphylactic human basophil degranulation via CD300a.9
249584592014PPARβ/δ activation of CD300a controls intestinal immunity.17

Citation

Dessen P

CD300A (CD300a molecule)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/40111/img/css/lib/haematological-explorer/