CTSE (cathepsin E)

2003-06-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
CATE

Other Information

Locus ID:

NCBI: 1510
MIM: 116890
HGNC: 2530
Ensembl: ENSG00000196188

Variants:

dbSNP: 1510
ClinVar: 1510
TCGA: ENSG00000196188
COSMIC: CTSE

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196188ENST00000358184P14091
ENSG00000196188ENST00000360218P14091

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
LysosomeKEGGko04142
LysosomeKEGGhsa04142
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
MHC class II antigen presentationREACTOMER-HSA-2132295

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
351819762022Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer's disease.9
351819762022Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer's disease.9
302782642019The Relationship between the Concentration of Cathepsin A, D, and E and the Concentration of Copper and Zinc, and the Size of the Aneurysmal Enlargement in the Wall of the Abdominal Aortic Aneurysm.7
302782642019The Relationship between the Concentration of Cathepsin A, D, and E and the Concentration of Copper and Zinc, and the Size of the Aneurysmal Enlargement in the Wall of the Abdominal Aortic Aneurysm.7
253487782015High Expression of Cathepsin E in Tissues but Not Blood of Patients with Barrett's Esophagus and Adenocarcinoma.10
253487782015High Expression of Cathepsin E in Tissues but Not Blood of Patients with Barrett's Esophagus and Adenocarcinoma.10
242423302014Repression of cathepsin E expression increases the risk of mammary carcinogenesis and links to poor prognosis in breast cancer.13
244649562014Role of cathepsin E in decidual macrophage of patients with recurrent miscarriage.10
252395632014Cathepsin E promotes pulmonary emphysema via mitochondrial fission.19
242423302014Repression of cathepsin E expression increases the risk of mammary carcinogenesis and links to poor prognosis in breast cancer.13
244649562014Role of cathepsin E in decidual macrophage of patients with recurrent miscarriage.10
252395632014Cathepsin E promotes pulmonary emphysema via mitochondrial fission.19
234510822013Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis.24
234510822013Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis.24
216649912012Emerging roles of cathepsin E in host defense mechanisms.15

Citation

Dessen P

CTSE (cathepsin E)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40204/gene-fusions-explorer/teaching-explorer/