RCAN2 (regulator of calcineurin 2)

2003-12-01  

Identity

HGNC
RCAN2
LOCATION
6p12.3
LOCUSID
10231
ALIAS
CSP2,DSCR1L1,MCIP2,RCN2,ZAKI-4,ZAKI4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10231
MIM: 604876
HGNC: 3041
Ensembl: ENSG00000172348

Variants:

dbSNP: 10231
ClinVar: 10231
TCGA: ENSG00000172348
COSMIC: RCAN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172348ENST00000306764Q14206
ENSG00000172348ENST00000330430Q14206
ENSG00000172348ENST00000371374Q14206
ENSG00000172348ENST00000405162A0A0A0MSB6

Expression (GTEx)

0
50
100
150
200
250
300
350
400
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Thyroid hormone signaling pathwayKEGGhsa04919

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
375351482023USP7-mediated JUND suppresses RCAN2 transcription and elevates NFATC1 to enhance stem cell property in colorectal cancer.1
379185832023CircIQGAP1 regulates RCAN1 and RCAN2 through the mechanism of ceRNA and promotes the growth of malignant glioma.0
375351482023USP7-mediated JUND suppresses RCAN2 transcription and elevates NFATC1 to enhance stem cell property in colorectal cancer.1
379185832023CircIQGAP1 regulates RCAN1 and RCAN2 through the mechanism of ceRNA and promotes the growth of malignant glioma.0
357337832022Association Between Circulating Regulator of Calcineurin 2 Concentrations With Overweight and Obesity.0
357337832022Association Between Circulating Regulator of Calcineurin 2 Concentrations With Overweight and Obesity.0
341465822021A novel transcriptional complex on the VE-cadherin promoter regulated the downregulation of VE-cadherin in the Down Syndrome Candidate Region 1 isoform 1L-mediated angiogenesis.1
341465822021A novel transcriptional complex on the VE-cadherin promoter regulated the downregulation of VE-cadherin in the Down Syndrome Candidate Region 1 isoform 1L-mediated angiogenesis.1
317333052020The novel axis of YAP1, transcription enhancer factor 3 and Down Syndrome Candidate Region 1 isoform 1L is a common signaling pathway downstream of several angiogenic factors.3
317333052020The novel axis of YAP1, transcription enhancer factor 3 and Down Syndrome Candidate Region 1 isoform 1L is a common signaling pathway downstream of several angiogenic factors.3
303070522019Clinicopathological significance of RCAN2 production in gastric carcinoma.6
303070522019Clinicopathological significance of RCAN2 production in gastric carcinoma.6
296431192018Regulator of calcineurin-2 is a centriolar protein with a role in cilia length control.12
296431192018Regulator of calcineurin-2 is a centriolar protein with a role in cilia length control.12
280052672017Human gingiva transcriptome during wound healing.14

Citation

Dessen P

RCAN2 (regulator of calcineurin 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40365/css/lib/meetings/welcome