ECE1 (endothelin converting enzyme 1)

2003-05-01  

Identity

HGNC
ECE1
LOCATION
1p36.12
LOCUSID
1889
ALIAS
ECE
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1889
MIM: 600423
HGNC: 3146
Ensembl: ENSG00000117298

Variants:

dbSNP: 1889
ClinVar: 1889
TCGA: ENSG00000117298
COSMIC: ECE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117298ENST00000264205P42892
ENSG00000117298ENST00000264205A0A024RAB2
ENSG00000117298ENST00000357071P42892
ENSG00000117298ENST00000357071A0A024RAB0
ENSG00000117298ENST00000374893P42892
ENSG00000117298ENST00000374893A0A024RAF7
ENSG00000117298ENST00000415912P42892
ENSG00000117298ENST00000436918B4DKB2
ENSG00000117298ENST00000473505E9PJG1
ENSG00000117298ENST00000481130E9PHZ1
ENSG00000117298ENST00000527991E9PN99
ENSG00000117298ENST00000649812A0A3B3ISF9

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
366357572023CircNDC80 promotes glioblastoma multiforme tumorigenesis via the miR-139-5p/ECE1 pathway.10
372710442023Mutation analysis of the ECE1 gene in late-onset Alzheimer's disease.0
375591402023CircECE1 promotes osteosarcoma progression through regulating RAB3D by sponging miR-588.1
366357572023CircNDC80 promotes glioblastoma multiforme tumorigenesis via the miR-139-5p/ECE1 pathway.10
372710442023Mutation analysis of the ECE1 gene in late-onset Alzheimer's disease.0
375591402023CircECE1 promotes osteosarcoma progression through regulating RAB3D by sponging miR-588.1
356456132022Association of Endothelin-Converting Enzyme and Endothelin-1 Gene Polymorphisms with Essential Hypertension in Malay Ethnics.0
356456132022Association of Endothelin-Converting Enzyme and Endothelin-1 Gene Polymorphisms with Essential Hypertension in Malay Ethnics.0
317773012020Effects of ECE-1b rs213045 and rs2038089 polymorphisms on the development of contrast-induced acute kidney injury in patients with acute coronary syndrome.1
317889442020Endothelin-converting enzyme-1c promotes stem cell traits and aggressiveness in colorectal cancer cells.10
321078802020Association of ECE1 gene polymorphisms and essential hypertension risk in the Northern Han Chinese: A case-control study.2
321709812020The role of Candida albicans candidalysin ECE1 gene in oral carcinogenesis.33
322783082020Placental endothelin-converting enzyme-1 is decreased in preeclampsia.0
317773012020Effects of ECE-1b rs213045 and rs2038089 polymorphisms on the development of contrast-induced acute kidney injury in patients with acute coronary syndrome.1
317889442020Endothelin-converting enzyme-1c promotes stem cell traits and aggressiveness in colorectal cancer cells.10

Citation

Dessen P

ECE1 (endothelin converting enzyme 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40395/teaching-explorer/